Rajesh Kumar Dutta

Senior Research Associate @DukeUniversity, interested in #Liver #regeneration, #NASH, #NAFLD, and #AcuteLiverFailure (ALF).

[JCI insight @JCI_insight]

This aging-related communication axis helps explain why older age increases
MASLD incidence: https://t.co/AkHzX6OaAn

Anna Mae Diehl & team @DukeMedSchool describe an inter-organ aging axis in which hepatocytes determine the rate of organ aging during metabolic stress. The researchers used conditional KO mice to show loss of hepatocyte hedgehog signaling induces ferroptosis stress, lipid peroxidation, and cellular senescence.

The video shows blood perfusion in vivo after treatment with ferrostatin-1, representing restoration of hepatic blood perfusion in the liver and kidney.
@Rajesh_Dutta @TsanJen
@the_asci
#Aging #Metabolism

[Rohit Loomba @DrLoomba]

Anna Mae Diehl making a claim that Nash cirrhosis is a degenerative disease ⁦@AASLDtweets⁩ ⁦@NAFLDresearch⁩ ⁦@nagachalasani⁩ ⁦@NoureddinMD⁩ ⁦@LisaVWMD⁩ ⁦@DrHuangDQ⁩ ⁦@EASLedu⁩

[Rajesh Kumar Dutta @Rajesh_Dutta]

Published results of newly approved Alzheimer’s drug Leqembi.
Lecanemab in Early Alzheimer’s Disease | NEJM https://t.co/2PAIrOk6Dn

[U.S. FDA @FDA]

Today, we approved a new medication for the treatment of Alzheimer’s disease, the second of a new category of medications approved for Alzheimer's that target the fundamental pathophysiology of the disease. https://t.co/ZXJCUuTYPk

[Nature Portfolio @NaturePortfolio]

Identification and characterization of variants in HTR2C in people with severe obesity reveals a role for the serotonin 2C receptor in regulation of appetite, weight and behavior, according to a @NatureMedicine paper. https://t.co/0tJf8NYRGN

[eLife - the journal @eLife]

Our Talking Points collection has a bit of everything: @dgurdasani1 on COVID-19; @algoriphagus on scientists and Indigenous communities; @MsPhelps on publishing; @repro4everyone on reproducibility; and Luisa Massarani on South America.

Catch up below!
https://t.co/GBs63n7lKh

[Rajesh Kumar Dutta @Rajesh_Dutta]

@AppuKum74640209 Congratulations!

[Rajesh Kumar Dutta @Rajesh_Dutta]

My annual small donation to @Wikipedia. Support free knowledge! #iloveWikipedia https://t.co/sBBIUyui7O

[Rajesh Kumar Dutta @Rajesh_Dutta]

@BBCWorld why newsroom instead of newshour?

[Rajesh Kumar Dutta @Rajesh_Dutta]

@SaketGokhale Your data does not seem normalized.

[Rajesh Kumar Dutta @Rajesh_Dutta]

@ShreyaScilens @India_Alliance So true. Amazing quote!

[Rajesh Kumar Dutta @Rajesh_Dutta]

@Goodell_Lab @bcmhouston Congratulations!

[Rajesh Kumar Dutta @Rajesh_Dutta]

@shynivarghese @LabVarghese Congratulations!

[Rajesh Kumar Dutta @Rajesh_Dutta]

@Atul_Gawande Great work by non-profit organization # TB Alliance.

[Congress @INCIndia]

इतिहास में साहेब का हाथ बहुत ही तंग।
सुनकर मोदीवाणी फिर, रहे धुरंधर दंग।।

[CSIR-IMTech @CSIR_IMTECH]

CSIR Foundation Day Celebrations formal Welcome & Introduction of Speakers by Dr. Anil Koul. Special Guest address Mr. Andrew Ayre, British Deputy High Commissioner, Chandigarh graced the event.

[Rajesh Kumar Dutta @Rajesh_Dutta]

@hksoni2003 Hi

[Rajesh Kumar Dutta @Rajesh_Dutta]

@surendravikram Cool..

[CSIR, India @CSIR_IND]

Dr. Girish Sahni, DG, #CSIR meeting the Prime Minister of Australia, Mr. Malcolm Turnbull in presence of the Prime Minister @narendramodi

[Rajesh Kumar Dutta @Rajesh_Dutta]

@CSIR_IND @narendramodi Dr Girish Sahani is a great leader. Under his leadership CSIR will grow and achieve great heights for sure.