Rajib Gupta

Renal and GI pathology; special interests in MGRS, immunoEM and IgG4-RD; Johns Hopkins renal path alumnus; Associate prof at UC Davis.

[Rajib Gupta @RajguptaEM]

Mini case-series of crystal-storing histiocytosis (CSH) affecting predominantly glomerular loops with detailed literature review of renal CSH, images of one of the cases are depicted below, https://t.co/BgJsYIFHU4
@raghupillappa, @JZRenalPath, @CArnold_GI

[soda_troubles, I have faith in Discord. @set_fortess]

C3 glomerulopathy associated with anti-factor H autoantibodies in a child with inflammatory bowel disease
https://t.co/Amc8c9d1BP

[Jonathan Zuckerman MD PhD @JZRenalPath]

Pt with SLE and sjogren with hematuria and proteinuria. +++RF, low C3/C4, IgM-k MGUS. Biopsy revealed IgM-k dominant GN with cryo plugs + vasculitis + abundant pure microtubular deposits c/w cryoGN. Some deposits being engulfed by macrophages. #renalpath #pathtwitter #nephrology

[Grace Choung, MD 박영이 @grace_choung]

C3 Glomerulopathy with Occult Gammopathy Treated with Low-Dose, Fixed Duration Venetoclax - Kidney International Reports https://t.co/CBGyhWGoDV

[Ibrahim Mansoor FCAP @IbrahimManff]

Not every “cancer” is cancer.

IgG4-related disease can present as a hard mass in the salivary gland, pancreas, orbit, kidney, lung, and many other organs—often mimicking malignancy on imaging and clinically.

Before calling it a tumor: sometimes the immune system is the culprit.

[Boonyarit Cheunsuchon, MD @roboonya]

Acute phlebitis in an interlobular vein. Although commonly seen in acute cellular rejection, the lesion itself is not diagnostic for rejection per Banff classification.

[Renal Pathology Society @Renalpathsoc]

Click 👇 to read the entire case in focus:
https://t.co/7LFCD7VgNC

#renalpath #pathtwitter

[Grace Choung, MD 박영이 @grace_choung]

Clinical value of kidney immunodeposits and urinary complement activation fragments in IgA nephropathy - Kidney International Reports https://t.co/1Y39bMRKAQ

[Boonyarit Cheunsuchon, MD @roboonya]

Crescentic GN was rarely reported in amyloidosis. It's still unclear in this pt that the crescents were due to glomerular amyloid deposits or COVID-associated immune response.
https://t.co/RmqttuqhNE

[Jonathan Zuckerman MD PhD @JZRenalPath]

Exuberant capillary wall spicules in this case of amyloidosis, AHL type. Amyloid spike by EM ('Bart Simpson sign' coined by @JeanHouMD). #renalpath #pathtwitter #nephrology

[Grace Choung, MD 박영이 @grace_choung]

Unmasking The Great Masquerader with Mass Spectrometry - Kidney International https://t.co/aC7j8IWVb1

[Grace Choung, MD 박영이 @grace_choung]

Disappearance of the Defining Organized Ultrastructural Lesion in CLL-Associated Monoclonal Immunotactoid Glomerulopathy After Ibrutinib Therapy - Kidney International Reports https://t.co/h7J9lQtsDC

[Jonathan Zuckerman MD PhD @JZRenalPath]

Sometime the casts have eyelashes. Amyloidogenic variant of light chain cast nephropathy. #renalpath #nephrology #pathtwitter

[Boonyarit Cheunsuchon, MD @roboonya]

Full house immunostaining does not always mean lupus nephritis. Young man initially diagnosed with lupus MN, but proved with mass spec to be syphilis-associated MN
https://t.co/ZnkK8WUhFl

[Edgar V. Lerma 🇵🇭 @edgarvlermamd]

Diabetic Nephropathy (DN) with concurrent primary podocytopathy represents a distinct clinical entity characterized by nephrotic-range proteinuria, ultrastructural podocyte effacement and favorable response to immunosuppressive therapy ca. 2026 from @NDTsocial
#Nephpearls #ECNeph

Early renal biopsy incorporating Foot Process Width (FPW) assessment enables targeted therapy to mitigate ESKD progression in this high-risk phenotype.

https://t.co/tdJLMh1zMd

[Dr Geetika Singh @DrGeetikaSingh1]

#ECNeph More clues!

[Renal Pathology Society @Renalpathsoc]

Renal Pathology Society's Case in Focus
Middle-aged male with HTN & CKD presented with nephrotic range proteinuria
Rita Santarsiere & Nicolas Kozakowski
English: https://t.co/7LFCD7VgNC
Links to translations (Spanish, Portuguese, French, Chinese) in next post below
#renalpath

[Kanishk Gupta, MD @kanishk10246585]

19/M with exercise-induced rhabdomyolysis presenting as dialysis-dependent AKI.

Kidney biopsy showed acute tubular injury with reddish-brown pigment casts. Myoglobin IHC was strongly positive, confirming myoglobin cast nephropathy.

#NephPath #AKI #Rhabdomyolysis

[Wenyan Zhou @Zhou1217001]

#renalpath young F, NS, normal SCr. The material filling the microaneurysms with double contours was seen in glomeruli. Did not receive any anti-VEGF therapy. Gene test showed MMACHC mutation.

[soda_troubles, I have faith in Discord. @set_fortess]

Anti-glomerular basement membrane disease: variant forms and underlying mechanisms
https://t.co/tPoYUuOaep

[Boonyarit Cheunsuchon, MD @roboonya]

Multinucleated giant cells in glomeruli of 56 yo man with MPO positive crescentic GN. Usually more frequent in anti-GBM, these cells can also be seen in ANCA GN. Necrotizing arteritis noted in interlobular artery