Ruth Pepper

Nephrologist Royal Free Hospital London, UCLH @RoyalFreeNHS @UCLH interest lupus, vasculitis and all things glomerular. Aspiring photographer. Tennis obsessed

[Ruth Pepper @RealDr_Pepper]

Once a month, I (Dr. Pepper) am in the same clinic area as a Dr. Salt.
Makes my day every time.

[NEJM @NEJM]

In the latest video in our partnership with @DGlaucomflecken, the REGENCY trial investigating the efficacy and safety of obinutuzumab when added to standard therapy in patients with active proliferative lupus nephritis is explained.

Access the article for free: https://t.co/No1qb3aKeV

[KIReports @KIReports]

Long-term Follow-up of a #Glucocorticoid Minimising Regimen for the Treatment of Severe #ANCA Associated #Vasculitis

#VisualAbstract by @krishnadoctor1

https://t.co/rtjAzrs9fE

@stephenmcadoo @RealDr_Pepper @salama_alan @THKC1

[Tobias B. Huber @Tobias_B_Huber]

Published today: JCI - Passive transfer of patient-derived anti-nephrin autoantibodies causes a podocytopathy with minimal change lesions. @NicolaMTomas @hengel_f
https://t.co/wtpq2vFj50

[Ruth Pepper @RealDr_Pepper]

@DrNeilStone @uclh @drclaireroddie Yes! CAR-T in autoimmunity! Watch this space…

[Ruth Pepper @RealDr_Pepper]

Thrilled to be involved with a pioneering CAR-T trial in our patients with lupus with the fantastic #CAR-T team @uclh @drclaireroddie and our sponsor #Autolus
We desperately need better treatments for patients with kidney disease #lupusnephritis

[UCLH @uclh]

Three patients have received an innovative treatment for the most serious form of #lupus.

The clinical trial is the first in the UK to assess the potential of CAR-T therapy to treat a disease other than cancer.

https://t.co/xvlpTZdwrP

@UCLHresearch @uclcancer @ManchesterCRF

[Sanjeev Sethi @SethiRenalPath]

A paradigm change in management of Lupus Nephritis (LN)

In pts with proliferative LN & + anti-ds DNA, treatment should be aimed at immunological remission

Definition of response based on proteinuria is outdated

Lupus Nephritis:Redefining treatment goals
https://t.co/WFursEwHFZ

[Brendon Neuen @brendonneuen]

Whole pop UK linked data on >230,000 ppl with HF from @Fletcher_RA at #ESCCongress

- Ppl with CKD remain undertreated for HF despite being at 🔼 risk
- CKD contributes 2x to 🏥/☠️ than any other comorbidity
- Major opportunities to improve pop health

In press, @TheLancetPH

[Ruth Pepper @RealDr_Pepper]

Huge loss for the renal community. A hilarious friend, fantastic colleague and brilliant nephrologist.
Tubular extraordinaire. Ben will be so very much missed by us all.

[London Tubular Centre @LTubularCentre]

We are heartbroken to announce that Prof (Stephen) Ben Walsh, died peacefully on 30th Sept while surrounded by family & friends.

Both his family & @RenalUCL are raising funds to find a way to honour his memory and achievements. More info below:
https://t.co/AYdW7uXbz1

Ben's passion for science & medicine was an integral part of who he was. And after self-diagnosing with lung cancer 18 months ago, he decided keep his condition private to protect his clinical and academic work. Remarkably Ben continued to work throughout his illness, right to the very end, ensuring that his students, colleagues and patients were taken care of, and that all he had built would continue on.

There are no words to really express the profound sadness we feel, the loss of a dear friend, colleague and mentor. He will leave a very large hole in our lives and he will not be forgotten.

Details of funeral/memorial services will be made available in due course.

We're also requesting anyone with pictures or videos of Ben to upload these to the Google Photos or Dropbox links below. We've also attached a link to a Google Doc for messages of condolence you may wish to leave for the family.

Google Photos:
https://t.co/0sC5SFqjT1

DropBox:
https://t.co/5ruE31DGfn

Google Doc for condolences:
https://t.co/1sqhW5MBES

Donation Page for Memorial Fund:
https://t.co/AYdW7uXbz1

[Sri Lanka Society of Nephrology @SLNephrology]

Check out the star-studded precongress workshop of the academic sessions of the SLSON!
Conducted by the @RoyalFreeNHS @ucl as a @ISNkidneycare SRC project
✅In-depth update on the current state of diagnosis & Mx of GN
✅Case-based format
✅CPC
✅Discussions on challenging cases

[Ruth Pepper @RealDr_Pepper]

Game changing treatment with #SGLT2i #UKKW2024

With early use of SGLT2i, potentially delaying the start of dialysis for 26 years!

Even starting with GFR of 20, almost a 2 year postponement - time to prepare the patient for RRT.

[Ruth Pepper @RealDr_Pepper]

Here’s the evidence!
Significant reduction in risk of kidney disease progression

[Ruth Pepper @RealDr_Pepper]

Low levels of SGLT2i use in eligible CKD patients in primary care.
How can we do better and ensure patients have access to these renal-saving medicines?
#UKKW2024

[Ruth Pepper @RealDr_Pepper]

NICE guidelines.
Empa use in GFR down to 20ml/min
#UKKW2024

[Ruth Pepper @RealDr_Pepper]

@cheekaycheung great overview of IgA.
Take home messages:
Even with low levels of proteinuria, risk of ESRF with long term follow up @DannyGale_1
Future promising with new treatments on the horizon

[Ruth Pepper @RealDr_Pepper]

Highlight of #UKKW2024 ! Team Renal at @RoyalFreeNHS
Dinner with the MDT! 🏴󠁧󠁢󠁳󠁣󠁴󠁿
@philmasson2 @RidingAlex

[Ruth Pepper @RealDr_Pepper]

Thrilled to be in 🏴󠁧󠁢󠁳󠁣󠁴󠁿 for #UKKW2024
Looking forward to 3 days of nephrology, whisky and bagpipes

[Jamie Willows @jamiekwillows]

The UK has the best hyperkalaemia guidelines in the world, and they’ve just been updated.

No one can cover all 171 pages, but here are 3 quick important bits in a thread👇

https://t.co/pZpyHhXjJX

[ASN Publications @asnpublications]

IgA nephropathy can progress to kidney failure. This study found that outcomes in a large IgA nephropathy cohort are generally poor with few patients expected to avoid kidney failure in their lifetime https://t.co/1cJlGYM0dz

@DannyGale_1 @IgAN_JBarratt @Moinsaleem @neilturn

[Ruth Pepper @RealDr_Pepper]

#JuniorDoctorsStrike
Team of Consultants and PAs on the renal ward.
Missing the vital work our junior doctors do, keeping our kidneys patients safe.
@RoyalFreeNHS

[Ruth Pepper @RealDr_Pepper]

#EUVAS2022
Take home message re AAV and diffuse alveolar haemorrage
- haemoptysis ABSENT in 30-50%
- early diagnosis is key
- consider BAL if safe