Rebecca Cofsky

ID PharmD, advocates for appropriate antibiotic use at Reading Hospital, peppermint hot coco and chocolate connoisseur

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️🔥 @CIDJournal
A randomized controlled trial of efficacy and safety of Fecal Microbiota Transplant for preventing recurrent Clostridioides difficile infection
FMT therapy vs. placebo did not reduce CDI recurrence or death at 56 days. #idxposts #FMT https://t.co/kMBdUdfLMo

[Joseph Sassine @JosephSassineMD]

Happy to share our review of antiviral treatment of #monkeypox, co-authored with the amazing @EmilySiegrist4 and just published in @CIDJournal! @OUHealth @IDSAInfo @SIDPharm @PaulSaxMD #IDTwitter #TxID #TwitteRx #MedTwitter #OpenAccess

Short 🧵 (1/n)

https://t.co/EHEfwOTAaa

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕⚡⚡Ultrashort course antibiotics for suspected pneumonia 🤔
One quarter of hospitalized patients treated for pneumonia had oxygenation saturations ≥95% on ambient air. Outcomes were similar with 1-2 vs 5-8d of antibiotics @BradSpellberg #IDTwitter https://t.co/nIHeUlh1lQ

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

✴️Based on Nonclinical data & PK modeling:activity against Omicron subvariants retained for 6 months
FDA revised the Evusheld EUA to recommend repeat dosing every 6 months w a dose of 300mg of tixagevimab& 300 mg cilgavimab if pts need ongoing protection✴️ https://t.co/rVZmEodiOp

[Bug Pharmacist 💊🧫 Tim Gauthier @IDstewardship]

#StewardMeme

It’s not Zosyn deficiency. It’s probably not even infectious. Just saying…

[Clinical Infectious Diseases @CIDJournal]

Beta-lactam antibiotic therapeutic drug monitoring in critically ill patients: a systematic review and meta-analysis et al.

✅ Just Accepted
🔗 https://t.co/ig1eCQnegv

[CDC Flu @CDCFlu]

1/2: This week, CDC’s Advisory Committee on Immunization Practices voted to preferentially recommend the use of higher dose (Fluzone High-Dose and FluBlok) and adjuvanted (Fluad) flu vaccines over standard-dose flu vaccines for adults 65 years and older.

[FungalDoc: moved to bluesky @FungalDoc]

A new review article of Monkeypox in @OFIDJournal written by @Boghuma et al. Wonderful summary of the clinical and historical aspects of the newly emerging disease that each and every clinician should be aware of. #IDtwitter

[Bug Pharmacist 💊🧫 Tim Gauthier @IDstewardship]

👀 New C diff pub via @ASMicrobiology @JClinMicro 👉 https://t.co/HejiIhurk4

“These data support the safety of withholding antibiotics for selected hospitalized individuals with suspected CDI but negative toxin.”

#IDtwitter #TwitteRx @PeggyFund

[Megan Rech, PharmD, MS @MeganARech]

🚨📢First study from @EMPHARM_NET hot off the press!

High Prevalence of FQ-Resistant UTI Among US ED Patients https://t.co/oMMkauzLoW

@bfaine1 @ae_gross @CBthePHARMD @giles_slocum @DEZ_EM_Pharm @gavin_howington @RxEmergency @AM_EM_PharmD @AbbyMBaileyEM #TwitteRx

[Bug Pharmacist 💊🧫 Tim Gauthier @IDstewardship]

🚨 New article!

In this post @KrutiYagnikDO 💬 shares insights on IV push antibiotics, pulling from her experiences using this strategy within an OPAT program

📲 https://t.co/Zlo2qp1a1A

#IDtwitter #TwitteRx #OPAT

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

The role of therapy for positive PCR and negative toxin remains unclear
🆕💥💥Quasi-Experimental Noninferiority Study #JCM
supports the safety of withholding antibiotics for selected hospitalized individuals with suspected CDI but negative toxin #IDTwitter https://t.co/3TApluvcee

[Kyle C. Molina @kcmolinaID]

It turns out, most people can tolerate tedizolid for a very long time @OFIDJournal @TayMorrisette
https://t.co/QFAa7QMApP

[Rebecca Cofsky @Rebeccacillin]

@krutu8 @ClaeysKcclaeys @IDPharmD_Kate @emilylheil @SIDPharm @accpinfdprn @warnermeister This discussion is so timely. We are preparing for BCID2 implementation too! I am also interested in seeing examples. 🙂

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

iDIAPASON RCT🔥🔥
Myth busted
Comparison of 8 Vs 15 days of antibiotic therapy for Pseudomonas aeruginosa VAP in adults
NO differences in the composite or separate outcomes (90-day mortality or VAP recurrence) between short & long duration @BradSpellberg
https://t.co/z6xiaZJljI

[Brad Langford @BRxAD]

Nurses are pillars of health care and public health and vital partners in #antimicrobialstewardship! Thanks to all of your efforts during the pandemic!
#NursingWeek #ThankANurse
@RNAO @ontarionurses

[ASHE Journal @ASHE_Journal]

From @MsSmallsO, @mmPharmD, @keenanconazole : Pharmacist non-dispensing involvement in OPAT is an emerging trend in the US with wide variability in program structure and pharmacist tasks. A ratio of 1 OPAT RPh to 65-70 OPAT pts is proposed.
https://t.co/sL4o9H1f3c

[Erin McCreary @ErinMcCreary]

#ECCMID2022 Late Breakers🚨 SABATO trial—5330 pts assessed to enroll 213 with low-risk SAB. Early PO switch non-inferior to completing 12-16 total DOT with IV ABX & assoc w/shorter hospital LOS. important to diligently assess patients who are actually low risk before switch to PO

[JACCP @JACCPJournal]

Patients do not always receive appropriate antibiotics at hospital discharge. This reviews implementation strategies and pharmacist-supported interventions to optimize antibiotics during transitions of care https://t.co/zY0g8nnRdw @accpinfdprn