Slickpothead

Follow me for news for freedom, prosperity, & happiness. Seize your future & destiny & greatness! Crypto Expert / Entrepreneur / Man of God / Pothead / MBA

[Slickpothead @RelaxingVi57207]

@LevantWire Stupid is as stupid does

[Slickpothead @RelaxingVi57207]

@blknoiz06 @WatcherGuru Not until they kill crypto and bleed it dry

[Slickpothead @RelaxingVi57207]

@Hebitsukaiza117 @WatcherGuru Hitler is trump's second cousin.

[Massimo @Rainmaker1973]

A new shot literally regrows knee cartilage.

Researchers at Stanford Medicine have identified a novel strategy to regenerate articular cartilage in knees and potentially prevent or treat osteoarthritis (OA).

The method targets 15-hydroxyprostaglandin dehydrogenase (15-PGDH), an age-related enzyme—or "gerozyme"—that accumulates in aging tissues and drives degeneration.

In aged mice, small-molecule inhibitors of 15-PGDH, delivered systemically or via intra-articular injection, promoted cartilage thickening and regeneration of functional hyaline articular cartilage.

This occurred without recruiting stem or progenitor cells; instead, existing chondrocytes underwent transcriptional reprogramming to a youthful state, with reduced populations of inflammatory and hypertrophic/degradative cells and expanded matrix-producing articular chondrocytes.

The inhibitors also reversed natural age-related cartilage thinning, improved joint function, and—when administered after simulated ACL injuries—strongly mitigated post-traumatic OA progression and associated pain.

Human OA cartilage explants from total knee replacements responded similarly in vitro, showing decreased degradation markers and evidence of new articular cartilage formation.

Given that an oral 15-PGDH inhibitor has already completed Phase 1 safety trials for age-related muscle atrophy, the findings open a path toward disease-modifying, regenerative therapies that could delay or obviate the need for joint replacement surgery.

[Agarwal, P., Su, S., Ancel, S., et al. (2025). Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration. Science. DOI: 10.1126/science.adx6649]

[Slickpothead @RelaxingVi57207]

@OrderBookShow @elliotrades If they are the ones that made the Blackberry cell phone I'm in.

[EliZ @eliz883]

The longer the market downturn lasts and the weaker players are forced out, the greater the opportunities will be for those who remain in the game.

This is how markets have always worked.

Periods of fear weed out those without a plan, those who trade on emotion, and those seeking easy profits. But it is precisely these periods that lay the foundations for the most significant movements.

Big returns don’t come when everyone is euphoric. They come when most people have already given up.

Patience is rewarded. Impulsiveness is punished.

Stay disciplined, protect your capital and be prepared: when liquidity and confidence return, those who have stayed in the game will be in the best position to seize the opportunities.

[Slickpothead @RelaxingVi57207]

@HormuzLetter Never been a president that made so many deals to end a war. He's probably better at it than anyone to be honest. And he's not done yet, he's just getting started! He'll end the war 100's of more times and win the noble peace prize!!

[Slickpothead @RelaxingVi57207]

@CastilloTrading Bet on this or Castillo will hunt you down and kick down your door!

[Castillo Trading @CastilloTrading]

Max by KO tonight ?

[Krown @KrownCryptoCave]

bitcoin:native on CME futs have reclaimed the 200sma & 5ema alongside bull div

nice.

[Matthew Hyland @MatthewHyland_]

The Macro backdrop IS NOT the important factor for #Crypto

In 2017 the balance sheet was reduced while there were rate hikes

In 2021 the balance sheet rose while rates were cut to zero

Polar opposites yet both produced majors runs

The common factor in both runs was the STEER TOWARD MORE RISK not the Macro backdrop

In 2026 we are finally seeing the steer toward more risk for the first times since 2009, 2012, 2016, 2020....

The steer toward risk to date has not been disproven in terms of being the most optimal conditions for crypto regardless of the macro backdrop in terms of rate cuts/hikes and easing/no easing

Therefore Crypto based on the steer toward risk starting again is at its highest opportunity before the optimal performance comes just like it did after 2012, 2016, and 2020

[Slickpothead @RelaxingVi57207]

@4NBT_Julius @TheCryptoDog @rowhale I got the tattoo on my forehead like you said Dog send me 2 Ethereum! Got fired cause of it and can't get a job anywhere.

[Slickpothead @RelaxingVi57207]

@DonLucassHere @MoonriverNW

[Slickpothead @RelaxingVi57207]

@Malclawdrummer @MoonriverNW

[Slickpothead @RelaxingVi57207]

@MoonriverNW Try HOOD Chain?

COIN is down 65% from ATH
$HOOD is up 79% from the lows and gunning for new highs

RobinHood Chain is thriving with new life, apps and energy

Base is dying and rudderless

Bryan Armstrong is allergic to engaging with community

[EllioTrades @elliotrades]

$COIN is down 65% from ATH
$HOOD is up 79% from the lows and gunning for new highs

RobinHood Chain is thriving with new life, apps and energy

Base is dying and rudderless

Bryan Armstrong is allergic to engaging with community

@vladtenev followed the leading meme coins on day one and knows cults like $GME are the backbone of his retail business

I can't help but feel that Coinbase is looking at a truly hellish path of losing their CEX biz and Chain biz at the same time

While RobinHood looks to eat the everything app cake and have it too

[Slickpothead @RelaxingVi57207]

@John_k_39 @Bitcoin_Teddy Interesting

[Slickpothead @RelaxingVi57207]

@CryptoJelleNL Maybe they are on their periods...? 🤔

[Slickpothead @RelaxingVi57207]

@LevantWire You are a bad liar

[Slickpothead @RelaxingVi57207]

@NoahRyanCo Interesting