@remeseiro-lab.bsky.social

Group Leader @UmeaUniversity & Wallenberg Fellow @WCMM_UmU. Postdoc @EMBL; PhD @CNIOStopCancer. Long-range gene regulation & 3D-chromatin organization in cancer

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

... and now it's real! 🤗 Out now @NatureComms!! Incredibly happy to see this work published and very proud of my team! #Enhancer #3Dgenome #Glioblastoma #CancerNeuroscience
https://t.co/qKBFApIUQ9

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

The PALS Summer School in Omis is back!
Register now for the 2026 edition 👇

[Claudio Cantù @ClaudioCantu81]

Registration for the PALS Summer School in Transcriptomics is Open 🧬 23-26 June 2026 https://t.co/N4V7RHGg5V
Join us in this wonderful place 🇸🇪 to learn
Theory & Computation from Famous Scientists in the Field
w @Remeseiro_Lab
Support by @scilifelab & @KAWstiftelsen

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

3D genome & Cancer 👇

[Jane Skok @jane_skok]

Last reminder: We’ll see you bright and early at 9:30 AM EST on the 25th to kick off #chromatin2025! Fantastic lineup of speakers with discussion to follow each talk. Don’t forget to register for this virtual meeting if you haven’t yet: https://t.co/wCtEJhT7Gl

[The Brain Prize @BrainPrize]

The Brain Prize 2025 #webinars uncover how the nervous system drives and responds to cancer - from brain tumours to neural circuit remodeling and cancers outside the brain.

https://t.co/l0WPUM5ZwB

#CancerResearch #Neuroscience #TheBrainPrize

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

@guillaumeandrey @ssmfgrants Thanks Guillaume! 🤗 Hope everything is going alright for you!

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

✨ Excited to share I’ve received a @ssmfgrants #Consolidator grant!
📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics
🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Apply 👇
https://t.co/WfH6R4ev4U

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Apply and join my lab at @umeauniversity 🇸🇪 and @WCMM_UmU , generously funded by @ssmfgrants #Consolidator, @Vetenskapsradet @Cancerfonden @KAWstiftelsen

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Work funded by @KAWstiftelsen @Vetenskapsradet
@Cancerfonden #StratNeuro #Kempestiftelsen #CancerforskningsfondenNorrland
📍@umeauniversitet @WCMM_UmU

Collab with @cemalerdeme @Kirkeby_Lab @Hornblad_lab

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

#GABAergic neuron-to-glioma synapses were recently found in #DMG/#DIPG, but not #GB @michelle_monje
@TaraBarronPhD
Yet our ML-based analysis flagged #GABA signalling as key in #GB. Notably, we showed that #GABAergic neurons promote #GB cell proliferation in co-culture assays.

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

With these studies we have showed that #epigenetic regulators of the #neuron-to-glioma axis can serve as actionable #targets in #GB.
Viewing neuron-glioma interactions through an epigenetic lens helped us understand how glioma cells exploit neural signals to fuel their growth.

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

#glutamatergic neuron-to-glioma synapses were found in #glioblastoma — key findings from @Winkler_Lab
@michelle_monje
We showed the SMAD3-PITX1 GRN drives this crosstalk. SMAD3 inhibition + neural activity boosts #GB growth in co-culture with glutamatergic neurons and in vivo.

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

📣 New pre-print from the lab: 👉 “Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML #GBM
📝 Read the #BioRxiv here:
https://t.co/TGhe34qcE2

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Among the new #GRNs that we identified, #GABA signalling emerges as a previously unrecognised player in #glioblastoma.

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Now we applied #MOBILE, a #ML based method, to integrate #multiomics data from #GB and uncovered new #GRNs and #TFs relevant for #glioblastoma pathogenesis.
📝 https://t.co/TGhe34qcE2

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Over a year ago in @natcomms we showed how rewiring of #enhancer landscape & #3Dgenome underlies #neuron2glioma synaptic communication in #GB. SMAD3 & PITX1 emerged as key #TF and targeting them alters tumour growth.
https://t.co/mvV2pvlGqq

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

📢 New pre-print:
“Gene regulatory networks linked to GABA signalling emerge as relevant for glioblastoma pathogenesis” #Glioblastoma #GB #GRNs #multiomics #GABA #CancerNeuroscience #ML

BioRxiv: https://t.co/hOTzmrUiOt...

🦋 Read a full thread here:
https://t.co/KadIRq0L63

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

👇about our work!

[Scientia @scientia_social]

Unlocking the secrets of glioblastoma! Dr Silvia Remeseiro maps the epigenetic landscape of this aggressive brain cancer, paving the way for new treatments. https://t.co/OZgk9T70sc Read more: https://t.co/qL8g2IcBuL @Remeseiro_Lab

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Follow me Bluesky from now on:
@remeseiro-lab.bsky.social

[@remeseiro-lab.bsky.social @Remeseiro_Lab]

Looking for a #GroupLeader tenure-track position?
👇 Check-out and don't miss this opportunity to start your research group with really good funding!
https://t.co/cA5CttGmLt
@WCMM_UmU @umeauniversity