Richard James

AMR; antibiotics; bacteriocins; diagnostics; expert witness; infection prevention; Legionella; NGS; FMT; superbugs. Prof Micro, Univ Nott Med Sch (retired)

[Richard James @RichardJames39]

@ECDC_EU data on the incidence of cases, attributable deaths and disability adjusted life years due to MDR bacterial infections in the EU in 2015 https://t.co/sPStfnaTih

[Richard James @RichardJames39]

@BioMickWatson I nominated Sir Alexander Fleming for the discovery of penicillin

[Richard James @RichardJames39]

[Open access] article reviewing "The evolving response to antibiotic resistance (1945-2018) https://t.co/7zJ3H1U08C

[Richard James @RichardJames39]

Interesting Open access study of MDR Gram-negative bacteria in hospitalized patients with complicated UTI's https://t.co/02qlparJxe

[Richard James @RichardJames39]

@DanWalkerLab The effect of antibiotics on the microbiome can be dramatic and persist in offspring

[Henrik M. Roager @HRoager]

Here we show (in rats) that #antibiotic exposure during pregnancy affects the development of the intestinal #microbiome in offspring and causes changes in body weight persisting into adulthood https://t.co/WhE9fJEQDK #earlylife @foodDTUdk @NEXSKU

[Richard James @RichardJames39]

AMR Control 2018 published by Global Health Dynamics in association with the World Alliance Against Antibiotic Resistance (WAAAR) is available here https://t.co/kDLQaj0PgK

[Richard James @RichardJames39]

Science article about arylomycin derivatives engineered at Genetech that are active against a range of Gram negative pathogens in mice https://t.co/T8qXEQXuCO

[Richard James @RichardJames39]

@ABpreservation @SouthAfricanASP You can join the event live or watch the webcast at https://t.co/L5J0lvjYKP

[Richard James @RichardJames39]

Interesting review concludes that maintaining a complex gut microbiota that fills up metabolic niches, resists pathogen colonization and boosts immune defenses has now become a crucial part of our efforts to fight against infectious diseases. https://t.co/UJ7uxNweED

[Richard James @RichardJames39]

FDA Unveils Plan to Combat Antibiotic Resistance by supporting antibiotic innovation and ensure that antimicrobial drugs are used according to good stewardship practices at a live event tomorrow https://t.co/L5J0lvjYKP

[Richard James @RichardJames39]

Interesting use of a thermoresponsive phage to deliver DNA to the GI tract https://t.co/qPJ9tW7uXm

[Richard James @RichardJames39]

Very interesting Open Access review of factors contributing to global AMR concludes that reduction of antibiotic consumption will not be sufficient to control AMR https://t.co/E7UC1UGbv5

[Richard James @RichardJames39]

Interesting article on the adaptation of a commercially available phage mixture used for treating UTIs that increased the sensitivity of 118 uropathogenic strains from 41% to 75% https://t.co/kNScunsWfc

[Richard James @RichardJames39]

Paratek obtains FDA approval for its antibiotic Omadacycline for treating both acute bacterial skin infections and community-acquired bacterial pneumonia.
https://t.co/GRGXCDdnmy

[Richard James @RichardJames39]

The Director of the Dr Foster Research Unit at Imperial College reports that UK Hospital sepsis deaths have increased by a third in 2 years https://t.co/TIsgLzSWEf

[Richard James @RichardJames39]

Faster DNA sequencing technology developed by Omniome raises $60 million in a Series B funding round https://t.co/Ffcpv1UVdj

[Richard James @RichardJames39]

Illumina founder launches cloud-based sequencing software Galileo AMR to monitor antibiotic resistance in Gram-negative bacteria https://t.co/ChAcpe3BLk

[Richard James @RichardJames39]

Record series A biopharma investment but anti-infectives still fairly small https://t.co/GjjEpKAPAm

[Richard James @RichardJames39]

The carbapenem, Tebipenem, offers an oral option, particularly as step-down therapy in the treatment of serious Gram-negative infections. https://t.co/3PK6yYY4zc

[Richard James @RichardJames39]

Plant-expressed phage lysins provide better control of C.perfringens on cooked meat than nisin https://t.co/ZjYFOcgZKY