#CKD care is not one-size-fits-all 🧩🩺
From prevention ➝ end-of-life, goals shift:
🟢 guideline-driven therapy
🟡 individualized treatment
🔴 symptom-focused care
Key principle: align #GDMT with life expectancy, function & patient priorities 🤝❤️
https://t.co/jEAWS6ukkV
Long-awaited SURPASS-CVOT: Cardiovascular Outcomes with Tirzepatide vs Dulaglutide in NEJM: #tirzepatide noninferior to #dulaglutide for 3-point MACE in T2D with ASCVD, with greater improvements in weight, A1c, BP, triglycerides, and kidney function.
https://t.co/Wzx7dOLTsC
Combination therapy as a new standard of care in CKD - multiple trials testing new therapies in combo with SGLT2i
- ARCTIC/PACIFIC trials: Baxdrostat/dapa vs. dapa
- EASi-KIDNEY: Vicadrostat/empa vs. empa
- ZENITH-HP: Zibotentan/dapa vs. dapa
https://t.co/gxVrfEQDvs
#ERA25
Aldosterone-targeted therapies: early implementation in resistant hypertension and chronic kidney disease
Aldostérone synthase inhibitors may emerge as a therapeutic option for patients with Treatment-resistant hypertension
https://t.co/Y0yU8rexqg
Opinion atrticle
SGLT2 inhibitors and new frontiers in heart failure treatment regardless of ejection fraction and setting
Interesting future Perspective
https://t.co/1YwrjBsvbf
@mmamas1973
HFmrEF/HFpEF can’t wait
Rx the 3 🏛️
SGLTi + nsMRA + GLP-1 RA (if obesity)
The optimal strategy is simultaneous or rapid sequence initiation to all eligible patients, without delay
@gcfmd@JavedButler1@DCRINews@JAMACardio
https://t.co/OsmCRZXMcK…
"Because the rise in obesity is forecasted to continue throughout the world, political commitment to transform the diets of all children and adolescents within sustainable global food systems is now urgent".
@ShivaniM_KC@DrDita@SaimeFulya
https://t.co/ilDoYXMego
SGLT2 inhibitors associated with a lower risk of atrial arrythmia and SCD in people with T2 diabetes and/or heart failure or chronic kidney disease.
A meta-analysis of 38 randomized controlled trials
https://t.co/rZPnKsVACK
3 Pillars of Medical Therapy for HFmrEF/HFpEF
*⃣ SGLTi + nsMRA + GLP-1 RA (if obesity) *⃣
The optimal strategy is simultaneous or rapid sequence initiation to all eligible patients, without delay.
@gcfmd@JavedButler1@DCRINews@JAMACardio
https://t.co/yNDUGCJw4P