Results of the open label TAPIR trial: glucocorticoid discontinuation in GPA #ANCA vasculitis.
▶️ higher number of relapse at 6 months for the discontinuation group
▶️ but driven by minor relapses and by subgroup not treated but Rituximab. @DrPeterMerkel#vasculitisBCN2024
Post-hoc PEXIVAS analysis: no effect of reduced GC dose on kidney recovery. Faster kidney recovery with PLEX but no sustained effect beyond 3 months.
1️⃣ real PLEX effect vs convection effect?
2️⃣ how about stratification by histological class? @odlerb#vasculitisBCN2024
Bravo à la team @FondsImmunov qui a couru ce matin le semi-marathon de Paris pour la recherche sur les maladies auto-immunes et inflammatoires !!
Maintenant c’est à vous, vos dons sont essentiels 👉 https://t.co/Ry9pU5d7aY
Merci pour votre soutien 🙏
Somatic mutations in UBA1 cause VEXAS, a severe inflammatory syndrome. For the first time, researchers have found 74 people with the mutation who don't have VEXAS. Studying them may give a peek into the earliest phases of disease.
In A&R
https://t.co/vrknbiYBMK
@rheumrob
Maintenance of AAV by RTX, based on B cell repop or serological flare (ANCA rise), after receiving at least 2 years treatment with RTX: more relapses in the ANCA rise group. ie: wait longer for treatment = more relapses. No placebo control group though. https://t.co/OeIBU211Zv
Congratulations to @glomwhisperer (Thibaut d'Izarny-Gargas) and JP Duong for this fascinating work which highlights the renal vasculature as a target during MPN-associated vasculopathy. Thanks to all contributors!
https://t.co/lyQcW1upPX
Une enquête menée par une équipe de Nantes s'intéresse aux habitudes des néphrologues concernant leurs prises en charge.
Vous êtes néphrologue et vous souhaitez participer ? C'est ici: https://t.co/w1OAAIrlhW
[Participation Enquête]
L’infection des kystes rénaux est une complication classique des patients ayant une polykystose rénale autosomique dominante. Pourtant, peu de données sont publiées à ce sujet…
🆕CD44 – parietal-epithelial cell staining in minimal change disease: association with clinical features, response to corticosteroids and kidney outcome
📖https://t.co/ydlpgm7dA4👈