Subhojit Roy, MD, PhD

Science. Music. Sometimes funny.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

Massive 10+ year effort in lab spearheaded by @leonardoaparrar and Kayal (secret account 🤔). Unreal cover by @EmmaVIDALL that says it all.

[Neuron @NeuroCellPress]

2023's final issue is out! https://t.co/ImgPc6z4Dp
Cover story is from @Roy_Lab_Thinks's lab revealing an unexpected physiologic role for α-synuclein phosphorylation in clustering synaptic vesicles and restricting neurotransmitter release. Read it here https://t.co/8SSr68cHRb

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

Front of paywall link: https://t.co/T9UeA6Wz8S

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

I'm obsessed with these empty clathrin cages people are seeing in neurons, and don't understand why others are not. So I put everything together and wrote a brief review (Current Opinion in Neurobiology, free access for 50 days):
https://t.co/hA4cmIiS0Q

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

..pic above reproduced from @MishaKudryashev 's publication in PNAS.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

@Ali_SyedRaza To be fair everyone bowled poorly but Arshdeep is consistently poor in the death overs. Plus he's an idiot so it's an easy call.

[Itai Yanai @ItaiYanai]

1. CRISPR came from basic research on bacteria.
2. Optogenetics started with a discovery in algae.
3. The GFP protein comes from jellyfish.
The biggest breakthroughs all trace to scientists follow their curiosity. This is one huge reason why we must keep funding basic research!

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

...on that note I'm kinda excited to give a talk at Rosalind Franklin University in Chicago next Wednesday 4/4

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

Bit obsessed by this...Franklin not only recognized the helix but also calculated each turn in spiral—34 Ang—and # of bases per Helix. And yet we have Watson's version where he goes on/on about the right pic (#51) that has no notes v/s left pic (#49) that has extensive notes 1/4

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

"No wonder Franklin recorded little in her notes about photograph 51..she saw no need to repeat herself. [She] knew exactly what’s in front of her”

https://t.co/bzw6eZSluK?

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

Because history is written by winners of course.
3/4

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

The main job university admins seem to have is to scrape the Internet for any possible favorable ranking by any random source.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

It was a three chocolate milk day.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

"No wonder Franklin recorded little in her notes about photograph 51..she saw no need to repeat herself. [She] knew exactly what’s in front of her”

https://t.co/bzw6eZSluK?

[Stanford University @Stanford]

The most important briefings of the day.

Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

"Pan didn’t know it at the time but he was racing against research groups across the United States and around the world to put channelrhodopsin into neurons"

https://t.co/LTV2rzfB1S

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

Morning light and afternoon sun.

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

There are worse ways to prepare for a talk #janeliafarms

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

lol: https://t.co/qt7LUQSS7x

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

I remember watching it every week in the 80s

[The Paperclip @Paperclip_In]

Humlog, the iconic Doordarshan TV serial, was a masterclass in storytelling that captured the essence of Indian middle-class life in the 1980s. However it traces its origin to the most unlikely inspiration: a sewing machine revolution that rocked Peru. Thread. 1/21

[Subhojit Roy, MD, PhD @Roy_Lab_Thinks]

It was so much more interesting to read about Diego Córdoba and Luis Martínez-Zoroa, rather than a stupid machine that spits out numbers.
https://t.co/KUaJrJtmlu