Ryan Cook

Viral ecologist with @EvelienAdri at @TheQuadram | All things phage (but mostly viromes) | Formerly at @UniofNottingham with @milja001 | All opinions my own.

[Ryan Cook @RyanCookAMR]

During my PhD, @milja001 and I started counting phage genomes, and tried to make them available in useful formats with useful metadata. We also described the extent of sequenced phage genomes at the time. Five years on, we've had a look at what's changed

https://t.co/7ugkeq08Rg

[Guido Valverde @GuidoValverde_]

Delighted to see our work featured as a Research Highlight in @NatureEcoEvo 🧬
Ancient strep throat 🦠
https://t.co/LvYdJBQfMw
😷 Strep throat is nothing new – a 700-year-old mummy proves it
🙌@msabrysarhan @RyanCookAMR
#Archaeology #aDNA #Genomics #StrepThroat #ScienceNews

[Ryan Cook @RyanCookAMR]

Happy to have played a small role in this cool piece of work led by @Teag4Phage in the lab of Evelien Adriaenssens. She looked at the impacts of using a phage cocktail in a batch-culture fermentation colon model 🦠 #phages

https://t.co/mvMMJP6EFk

[Ryan Cook @RyanCookAMR]

Been really fun to re-visit this with Branko Rihtman, @APonsero , @SMichniewski , @telatin , @TSPKU , Evelien Adriaenssens and @milja001

https://t.co/7ugkeq08Rg

[Ryan Cook @RyanCookAMR]

During my PhD, @milja001 and I started counting phage genomes, and tried to make them available in useful formats with useful metadata. We also described the extent of sequenced phage genomes at the time. Five years on, we've had a look at what's changed

https://t.co/7ugkeq08Rg

[Ryan Cook @RyanCookAMR]

We're also putting out a fully updated pipeline with defence (and anti) predictions, lifestyle predictions and other fun improvements. Community involvement in this project has been great over the last 5 years and I hope this continues!

[Ryan Cook @RyanCookAMR]

Really happy to have played a small part in this cool piece of work led by @GuidoValverde_ & @msabrysarhan. We characterised S. pyogenes in a pre-Columbian Bolivian mummy (suggesting circulation before European contact) #VivaBolivianMummies

https://t.co/XAksdOjDcL

[bioRxiv Genomics @biorxiv_genomic]

Salmonella Genomic Markers for Risk to Food Safety https://t.co/Ob97Mq5qA8 #biorxiv_genomic

[Ryan Cook @RyanCookAMR]

Really enjoyed writing a piece for @ConversationUK - trying to write for a general audience, you suddenly realise how much jargon is deeply embedded in your brain #Phages #Microbiome #SciComm

https://t.co/zX4nys3uNf

[Ryan Cook @RyanCookAMR]

Happy to say this has now been published in @CellReports 🫁🦠 #Phages #Viromics

https://t.co/ZjZkQc2FEm

[Ryan Cook @RyanCookAMR]

New pre-print alert! 🚨🫁

COPD affects millions worldwide. While we know bacterial dysbiosis drives disease, the role of bacteriophages remains unexplored. We re-analysed 135 COPD metagenomes to characterise the lung virome for the first time 🫁 1/9
https://t.co/5SlpGYOLHA

[Ann Gregory, PhD @gregory_annc]

🚨 We’re hiring! 🚨

The Integrative Viromics Lab @UCalgary is looking for a Lab Technician to join us starting November 2025.

🔬 Phage isolation & culture
🧫 Anaerobic chamber work
📦 Lab management & student mentoring

Apply now & help us explore the virosphere!

[George Bouras @GB13Faithless]

Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation

[Andrew millard @milja001]

After hiatus, as @RyanCookAMR were a bit busy .... we have updated links to latest INPHARED dataset. With 37.5K genomes now

https://t.co/hIuU2F70Z6

[Franklin Nobrega @NobregaFL]

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription.

Huge congratulations to @ugobananas_uuu @Zhangzhiyi58692 and @TCTodeschini, and to all our collaborators.

https://t.co/isqlJ06hjw

[Ryan Cook @RyanCookAMR]

This is probably my last piece of work from my
@MedResFdn funded PhD at @UniofNottingham (thanks for all the support over the years!).

Contributions from @milja001 @APonsero (and many others not on here) 13/13