Sangeetha N Kalimuthu

GI/Pancreas/Soft Tissue Pathologist, University Health Network, Toronto, inveterate morphologist, ardent admirer of the spoken word, pudding fancier

[Sangeetha N Kalimuthu @SNKali]

@JLHornick @TBrennster Deepest condolences. A true doyen of pathology, he will be so missed.

[Sangeetha N Kalimuthu @SNKali]

@RunjanChetty Thanks Runjan; yes, I remember hours of us deliberating over the features and terminology.

[Sangeetha N Kalimuthu @SNKali]

Congratulations on this important study. Thanks for recognizing our work.

[Rémy Nicolle @RemyNicolle]

Happy to share our work with @OwkinScience on a daring challenge:

Can #PDAC epithelial and stromal molecular phenotypes be identified from standard histology slides?

Better yet, can this help resolve intra-tumor heterogeneity?

a thread 🧵

https://t.co/p95nAcd88S

[Sangeetha N Kalimuthu @SNKali]

@cros_jerome @RemyNicolle :) thank you. After all, this was our nod to Gleason grading and demonstrating the power of morphology.

[Sangeetha N Kalimuthu @SNKali]

@RemyNicolle I am humbled.

[Susan Prendeville @s_prendeville]

My face while missing out on #USCAP2022 in-person experience ... looking forward to New Orleans in 2023! 🤞🙂

[Sangeetha N Kalimuthu @SNKali]

@WeinrebIlan Congratulations Ilan 👏🏻

[Sangeetha N Kalimuthu @SNKali]

@WeinrebIlan @histiocytosisX Amazing case!

[Sangeetha N Kalimuthu @SNKali]

@PaPathfinder @Canadian_PEh Pleasure, thank you for inviting me!

[Genome Biology @GenomeBiology]

scSNV, from, @jonyeung and co, a method for identifying variants in droplet scRNA-seq data. It takes advantage of molecular duplicates to collapse duplicate reads into longer molecules. It has filters to remove common sources of false positive SNVs https://t.co/S7sMBvlSOY

[Sangeetha N Kalimuthu @SNKali]

@s_prendeville These are phenomenal images Susan!

[Sangeetha N Kalimuthu @SNKali]

@KhaleelAlObaidy @s_prendeville @drmehrarohit Great case Susan.

[Sangeetha N Kalimuthu @SNKali]

Dying in a Leadership Vacuum | NEJM https://t.co/ssadxHvUSe

[Susan Prendeville @s_prendeville]

Mucinous Cystic Neoplasm of the liver
➡️Similar to its more common counterpart in the pancreas

🔸 Female
🔸 Mucinous lining
🔸 Ovarian-type stroma; ER/PR +
🔸 May show high grade dysplasia and rarely associated invasive carcinoma

#GIpath #liverpath #pathresidents @PathSpotters

[Sangeetha N Kalimuthu @SNKali]

@BrianHayes1982 Thanks Brian. Hope all’s well with you too.

[Sangeetha N Kalimuthu @SNKali]

My inaugural case on twitter. A true mixed adenoneuroendocrine carcinoma (amphicrine type) showing bivalent endocrine and exocrine differentiation. The tumour looked like a typical adenocarcinoma with focal areas demonstrating an organoid growth pattern.

[Sangeetha N Kalimuthu @SNKali]

@s_prendeville @olopeznu @seyma_buyucek @kkuanMD @LaraHarikMD @VarshaManuchaMD @DrBMcGinn Thanks for the tag Susan.
Name: Sangeetha
Speciality: Pathology, GI and soft & bone pathology
Interests: as I am a pudding fancier, I bake and like eating the products; painting
Tagging: @RunjanChetty @NischalanP

[Sangeetha N Kalimuthu @SNKali]

Anatomical location: Sigmoid colon

[Sangeetha N Kalimuthu @SNKali]

Synaptophysin and chromogranin are diffusely positive. Mucicarmine shows the presence of mucin droplets.
MIB-1 proliferation index=49.7%