PathSpotters

We are collecting cool Pathology spotters & cases in one place. If you have one, tag us. We will feature you! #pathspotter #pathtwitter

[Hansini Laharwani @HansiniMD]

Primary localized amyloid of the breast #breastpath #PathTwitter #MedTwitter #pathology
🍏Detected on screening mammography as clusters of calcifications
🍏 25% do not develop a hematologic disorder or systemic amyloidosis
🍏Apple-green on polarized light

[PathSpotters @PathSpotters]

Xanthoma

[Pathology Walker@Auto Tweet Bot @Patholwalker]

Xanthoma. Stomach, biopsy. #Pathologist #Pathology #GIpath

[PathSpotters @PathSpotters]

Balloon Cell Melanoma

[Simona De Michele, MD @SDeMicheleMD]

Balloon Cell Melanoma:
🔬Rare variant of MM in which cells have abundant clear cytoplasm
🔬IHC: HMB45+,S100+,MelA+
🔬DD: balloon cell nevi(lack atypia/mitosis),other clear cell tumors
🔬Prognosis: similar to other MM types @PathSpotters #PathTwitter #path #derm @ColumbiaPath

[PathSpotters @PathSpotters]

Chronic necrotising aspergillosis

[Santa Casa Pathology @PathologySp]

Chronic necrotising aspergillosis is locally invasive is seen in patients with immunodeficiency or chronic lung disease. Aspergilloma is a fungus ball that develops in a pre-existing cavity in the lung parenchyma. Acute angled dichotomous branching hyphae found in necrotic tissue

[PathSpotters @PathSpotters]

Bronchiectasis

[Daniela Hermelin, MD @HermelinMD]

✅Bronchiectasis. In addition to respiratory complications, children also develop pancreatic insufficiency & lose the exocrine pancreas leading to malabsorption and steatorrhea, as well as GI complications. https://t.co/DkmTH9B1c4

[PathSpotters @PathSpotters]

Warthin-like papillary thyroid carcinoma

[C. Christofer Juhlin @DrJuhlin]

Warthin-like papillary thyroid carcinoma.

🔬Papillae lined with oncocytic cells, with prominent lymphocytic infiltration of stalks. Tumor nuclei are enlarged, irregularly sized with grooves and occasional pseudo-inclusions. Background of lymphocytic thyroiditis.

[PathSpotters @PathSpotters]

Dedifferentiated Chondrosarcoma

[Brendan Dickson, MD @B_C_Dickson]

DEDIFFERENTIATED CHONDROSARCOMA. NB: juxtaposition of lower grade chondrosarcoma with an undifferentiated spindle-pleomorphic cell neoplasm; brisk mitotic activity; necrosis.

[PathSpotters @PathSpotters]

Kikuchi-Fujimoto Disease

[@Hemepathguy @hemepathguy]

REtweet Kikuchi-Fujimoto disease. Necrosis without neutrophils, increased plasmacytoid dendritic cells, CD123 positive

[PathSpotters @PathSpotters]

Zygomycosis

[PathSpotters @PathSpotters]

IgA Nephropathy

[Pathology Walker@Auto Tweet Bot @Patholwalker]

IgA nephropathy. HE, PAS, PAM and DIF(IgA). #pathology #pathology #nephropath

[PathSpotters @PathSpotters]

Fibrous dysplasia of bone

[Pathology Walker@Auto Tweet Bot @Patholwalker]

Fibrous dysplasia of bone. #pathology #pathologist #BSTpath

[PathSpotters @PathSpotters]

Aggressive NK/T cell leukemia

[Pathology Walker@Auto Tweet Bot @Patholwalker]

Aggressive NK/T cell leukemia. Gross and HE. #Pathology #Pathologist #Hemepath

[PathSpotters @PathSpotters]

Lipoblastoma

[PathSpotters @PathSpotters]

Mucinous metaplasia of the fallopian tube

[Susan Prendeville @s_prendeville]

Mucinous metaplasia of the fallopian tube

- Can be associated with Peutz-Jeghers syndrome and mucinous neoplasms at other sites
- Should exclude mucinous neoplasia elsewhere in female genital tract/GI

#pathresidents #gynpath

[PathSpotters @PathSpotters]

Hibernoma

[PathSpotters @PathSpotters]

Nodular Melanoma

[Texas Society of Pathologists @TexPathol]

Nodular melanoma: large profusely bleeding “skin tag" present for 3 months in the intergluteal fold. Positive for S100, Melan A, and HMB 45.Classic features: dermal-invasive melanoma with lack of significant radial growth phase (i.e. junctional component)

[PathSpotters @PathSpotters]

Metastatic Breast IDC with lobular growth pattern

[Texas Society of Pathologists @TexPathol]

Metastatic breast IDC with lobular growth pattern in the pleural cavity: Cytology showed abundant atypical cells with cannibalism. Cell blocks were positive for MOC31, GATA-3,��GCFDP-15, and negative for mucicarmine, ER, PR, HER2.

[PathSpotters @PathSpotters]

Multifocal Oncocytoma of Parotid

[Ilan Weinreb 🇮🇱🇨🇦 אילן וינרב @WeinrebIlan]

Multifocal oncocytoma/oncocytosis of parotid.

🔹multiple nodules, some circumscribed and some not.

🔹some can be clear cell rich.

🔹p63 should show an incomplete outer layer around the nests.

But wait…aren’t these supposed to be golden brown grossly? See final pic.

[PathSpotters @PathSpotters]

Solitary fibrous tumor/Hemangiopericytoma

[Pathology Walker@Auto Tweet Bot @Patholwalker]

Solitary fibrous tumor/Hemangiopericytoma, WHO grade I. Cerebrum, tumorectomy. HE and STAT6. #pathology #neuropath

[PathSpotters @PathSpotters]

Epithelioid GIST

[Gerônimo Jr. @GeronimoJrLapac]

#GIpath #pathology