Pabi Sahoo (ପବିତ୍ର ସାହୁ)

Assistant Professor at Rutgers University | Molecular Neurobiologist | Neural repair | Neurodevelopment

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Our CNS regeneration work is now online. Terrific postdocs @manasiagrawal1 and @meghaldesai completed the revision experiments. @RutgersSASN @RutgersU

https://t.co/eBTWbMhd9G

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Stress granules restrain ferroptosis by sequestering ferritin | Nature Cell Biology https://t.co/vLHXR8aYQG

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

First major grant for the lab. Thank you, #NJCBIR, for believing in us. Now let's get back to the bench to get that work done :)

[Manasi Agrawal, Ph.D. @manasiagrawal1]

This review was a great opportunity to take a step back and appreciate the progress in iPSC-based models for neural repair.

But can we truly model human neural repair?

Excited to share our review that discusses how far we’ve come in the field while highlighting what’s missing!

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Proteolytic cleavage of G3BP1 by calpain 1 couples NMDAR activation to mTOR-dependent local translation | EMBO Reports | Springer Nature Link https://t.co/bSpwMQzZvn

[Rutgers University @RutgersU]

Congratulations to 8 Rutgers researchers named fellows of the prestigious American Association for the Advancement of Science.

https://t.co/ldhZUnYmjq

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

How many axon localization elements are in one mRNA? mTor mRNA seems to have at least 3. Read this interesting preprint from the Fainzilber lab.
Multiple mTOR RNA localization signals regulate subcellular protein synthesis and axonal growth https://t.co/lM0uNqI2A0

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

There is a current push towards doing biological research using only hiPSC models, but are we there yet? @manasiagrawal1 nicely discusses it in this review using neural repair as a model system.
https://t.co/H6EdAXZdxf

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Ribosomal RNA expansion segments mediate the oligomerization of inactive animal ribosomes | Science https://t.co/ecC0oGNE2r

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

So it was an RNA world 🤔. A small polymerase ribozyme that can synthesize itself and its complementary strand | Science https://t.co/6EG5PPa0ce

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

@manasiagrawal1 Here is the preview video!

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Our methods paper is now online. It was co-led by Shruti Ghumra and @manasiagrawal1. If you are struggling with enriched axonal preparations, you may find this paper useful! JoVE https://t.co/EkNIHacd03

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

@manasiagrawal1 What an year for you, Manasi! Congratulations and best wishes for the next year!

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

It was exciting to introduce our lab and work to the Rutgers Neuroscience community. @meghal_desai @manasiagrawal1 did an amazing job! @BHI_Rutgers

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

@meghal_desai received a one-year Postdoctoral Fellowship from the
New Jersey Autism Center of Excellence (NJACE). Congratulations, Meghal, and thank you, NJACE, for supporting our research!

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

TRIM28-mediated SUMOylation of G3BP1/2 regulates stress granule dynamics: Cell Chemical Biology https://t.co/97VXCl7eNo

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

KIF5A binds RNA to orchestrate synaptic mRNA localization and stress granules in ALS | bioRxiv https://t.co/zEKfNyW2WY

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Super cool results from the ⁦⁦@jltwiss1⁩ lab. ⁩ Source: bioRxiv https://t.co/QGimfz9AnN

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Read this excellent story from the @jltwiss1 lab. Acetylation of Axonal G3BP1 through ELP3 Accelerates Axon Regeneration https://t.co/5TOcPagj3o

[Perlson lab @LabPerlson]

Thrilled to share our new work in Nature Neuroscience!

Together with amazing collaborators and led by Ariel Ionescu, we discovered that muscle-derived miR-126 controls local axonal TDP-43 synthesis and protects neuromuscular junctions in ALS.

https://t.co/FMksQim7eF

[Pabi Sahoo (ପବିତ୍ର ସାହୁ) @SahooLab]

Meghal and Shruti received the BHI travel award. Congratulations both!
https://t.co/tHnl2fxcCc