Translational Cardiomyology Lab @SCIL_Leuven @KU_Leuven | Investigating the mechanisms underlying muscle diseases at the single cell level | #myotwitter
No surprise. DNA repair again. Does someone think that CRISPRing few genes we will live forever...?
Whole-genome sequencing analysis of semi-supercentenarians https://t.co/rIPCTxSDqy
The Maurilio Sampaolesi Lab (@SampaLab) at Stem Cell Institute (@scil_leuven) optimize a protocol to generate chemically defined human-induced pluripotent #stem cell-derived #mesodermal progenitors. 📋
📰 @cddpress
📎 https://t.co/nGAyEGpUbc
Check out our latest publication where @NefeleG et al. identified "guide" cells - a subset of vessel-associated cells by #scRNAseq. Guide cells are able to improve myogenic differentiation without fusing with newly formed fibers. Impressive, isn't it?!
https://t.co/UH7tpiJ10C
Final project from my PhD is out. Tissue damage induces a conserved stress response that initiates quiescent muscle stem cell activation. This one was a lot of fun. Great collaboration with @RelaixLab with @LeoMachadodo @PhiliMour @FRelaix. https://t.co/TIaGuRCGFu
Happy to share the new GYM website, part of #InterregEurope. We will contribute to develop and commercially produce an innovative #stemcell#therapy for the treatment of patients with reduced #muscle mass, power and energy.
https://t.co/5HGj6pvdZs
@EnricoPozzoMD
@NefeleG
Proud to share my latest publication "MICAL2 is essential for myogenic lineage commitment". We investigated the impact that MICAL2 has on skeletal and cardiac muscle in healthy and regenerating conditions. Check it out. #stemcells#skeletalmuscle
https://t.co/Bios6RY2wi
Check out my #PhD work @CellReports. Through #singlecell#RNA sequencing, we discover an adipogenic regulatory cell type (Areg) in the skeletal #muscle that controls fat turnover. Huge implications for dystrophy patients that nearly have Aregs anymore.
https://t.co/SG0yx1tcmY
Great FWO news!
Maurilio Sampaolesi and his group received an FWO grant for the project:
3D vascularized cardiac organoid on-chip for modeling of dystrophic and mitogenic cardiomyopathy.
#FWO#kuleuven#mitogenic#cardiomyopathy