Oral NR treatment at 3000 mg daily for 4 weeks was safe, and NR even at a dose of 3000 mg for 4 weeks did not cause depletion of the methyl-group pool
https://t.co/eE3MFszA02
Seriously, though, IV NAD has been used to treat addiction for decades, and people swear by it, but I've seen no research comparing whether it works better than available NAD boosters. You'd think that kind of research would be warranted before a $5M spend to develop a new drug.
Patients with the rare metabolic disorder Arts Syndrome appear to have clinical improvement with SAMe and nicotinamide riboside
https://t.co/tlOZisDJCA
Radiation: Mouse study shows NR's potential to be a therapeutic agent for delayed effects of acute radiation exposure in patients receiving radiotherapy and exposed populations https://t.co/g0JuYlfC6g
🔬 Curious about cellular health and nicotinamide riboside? 🔬Participate in an insightful AMA with @CharlesMBrenner on the r/nicotinamideriboside subreddit. Ask your burning questions about Tru Niagen and discover how it supports your vitality. Join the conversation! https://t.co/xmoACirmzx #AMA #CellularHealth #TruNiagen #nicotinamideriboside
@Problematictv If you have any doubt that NMN gets converted to NR before it enters cells and replenishes NAD, you can read it 18 different ways in 18 different studies: https://t.co/xLhrmYloo8
It has been more than two years since scientists told us that vitamin B3 could treat sepsis. Since then, we have helped a lot of septic rodents. Now the CDC is trying to take sepsis more seriously.
https://t.co/MdZYENrcB0
NR supplementation blunts Th1 and Th17 immune responsiveness in healthy volunteers and in psoriasis. The concept is now being explored in vivo, where mild to moderate psoriasis patients are being investigated in a placebo-controlled study. https:// https://t.co/D6ib4imSPi
Meta-analyses of 29 random controlled trials with 8,664 participants indicated a significant reduction in systolic and diastolic blood pressure for the NAD+ precursors supplementation compared with the control group. https://t.co/pVQWhhqTsm
Preprint: "The evidence that psoriasis lesions show NADH/NAD+ redox imbalance towards oxidation may have important therapeutic implications....Increasing the level of NAD+ in psoriatic lesions could be considered as a therapeutic option..." https://t.co/pSQw3E4a1I
"Adipose-derived stem cells (ASCs) play a vital role in the regeneration of adipose tissue...These results suggest that NR treatment holds promise as a potential strategy to rejuvenate the stemness of aged ASCs."
@pranavsureshpn I rely on the big sales, like Black Friday and Prime Day, and occasionally in between, which offer significant discounts, enough to justify stocking up.
Diabetes: NR supplementation boosted NAD metabolism to augment mitochondrial function, reducing inflammation and thereby preventing progression of diabetic kidney disease in mice https://t.co/k7SkM3adr5