Scintillon Institute

The Scintillon Institute for Biomedical and Bioenergy Research is a 501(c)(3) non-profit research institute that is developing biologically-based technologies.

[Scintillon Institute @Scintillon]

https://t.co/ld0Jzj2JEe
Understanding the fundamentals of aging, e.g. mitochondrial dysfunction, is critical and insufficiently focused in the current healthy aging industry. The genetic tools developed here provide unique opportunity to test and predict rejuvenation strategies.

[Scintillon Institute @Scintillon]

New publication from #Scintillon revealed something else behind #mitochondrial #aging, from the Cracan lab--https://t.co/ld0Jzj2JEe, nicely summarized here https://t.co/9v91lIqdXR

[Scintillon Institute @Scintillon]

This year we also have a company, Defined Bioscience, in our incubator participating by hosting a student, giving them a taste of how basic research connects with product development.
https://t.co/ZfWil8Xt6o

[Scintillon Institute @Scintillon]

Dr. Irene Munk Pedersen from the Scintillon Institute with colleagues at Columbia University found targeting neutralization of microRNA-23b strengthens blood-brain barrier (BBB) function, accelerates repair, and reduces ischemic injury in stroke models.
https://t.co/SGClCeQcrQ

[Scintillon Institute @Scintillon]

The Scintillon Research Institute welcomed 12 talented students for the 2026 SURE Program, bringing another energetic group of young scientists into our laboratories for an immersive introduction to biomedical research.
https://t.co/ZfWil8Xt6o

[Scintillon Institute @Scintillon]

@Scintillon investigator Dr. Valentin Cracan @VFCracan and Dr. Andrey Parkhitko @parkhitko (@PittTweet) have been awarded two R21 grants from the NIH to study how redox metabolism shapes aging and cancer, and whether modulating it can delay both.
https://t.co/HkQ7lL51Lm

[Scintillon Institute @Scintillon]

A teaser of what Scintillon’s fundamental research can lead to new aging and cancer drugs from today’s special seminar by Dr. Valentin Cracan.

[Scintillon Institute @Scintillon]

Join us at Scintillon this Friday, 1 p.m., for an in-person seminar by Dr. Valentin Cracan to learn about his development of xenotopic tools for investigation of the role of redox imbalance in metabolic decline linked to aging, with fascinating potential for aging intervention.

[Scintillon Institute @Scintillon]

https://t.co/KThWqwxE38, Dr. Peter Adams on aging and Dr. Hideyuki Okano, President of International Society of Stem Cell Research (ISSCR) will give keynote speeches on Aging and iPSC and cell therapy approval. This FRIDAY at Catamaran Hotel in San Diego https://t.co/QlTiPCgLE8

[Scintillon Institute @Scintillon]

Our 1st annual Scintillon Institute Innovator Forum at the Catamaran Hotel in Pacific Beach is taking place this Friday, March 27! Come join us!
https://t.co/f24cpmsccL

[Scintillon Institute @Scintillon]

Come join us for our 1st annual Scintillon Institute Innovator Forum at the Catamaran Hotel in Pacific Beach on March 27. This year, we aim to bring together colleagues from academia and industry to discuss aging and rejuvenation research.

https://t.co/f24cpmsccL

[Scintillon Institute @Scintillon]

Dr. Peter Adams, Director of the Cancer Genome and Epigenetics Program at Sanford Burnham Presbys and PI of the San Diego Tissue Mapping Center, will be a speaker for our 1st annual Scintillon Institute Innovator Forum on 3/27 at Catamaran Hotel in PB.

https://t.co/f24cpmsccL

[Scintillon Institute @Scintillon]

Scintillon Scientific Advisory Board Member Professor Hideyuki Okano, President of the International Society for Stem Cell Research, will be a speaker for our 1st annual Scintillon Institute Innovator Forum on 3/27 at Catamaran Hotel in Pacific Beach.

https://t.co/f24cpmsccL

[Scintillon Institute @Scintillon]

Our 1st annual Scintillon Institute Innovator Forum will be held on March 27 at the Catamaran Hotel in Pacific Beach. This meeting aims to engage colleagues from academia and industry to discuss innovative topics such as aging and rejuvenation research.

https://t.co/f24cpmsccL

[Scintillon Institute @Scintillon]

Congratulations to @VFCracan and colleagues for developing a genetically encoded tool based on a bifunctional enzyme that can restore redox imbalance and modulate lipid metabolism in vitro and in a mouse hepatic steatosis model.
https://t.co/6Nhsq74c3f

[Valentin F. Cracan @VFCracan]

I am excited to share our newest paper, "A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity," which is now live in @NatMetabolism! This study was led by outstanding members of my lab @XingxiuPan and @smunan1995, in close collaboration with the @hardikshah42 lab at @UCCancerCenter and the @russpgoodman lab at @MassGenBrigham. In this study we present a genetically encoded tool based on a bifunctional enzyme that can regenerate NAD⁺ while simultaneously executing an engineered glycerol shunt. We used this tool, which we call CrGPDH, to restore redox imbalance and modulate lipid metabolism in vitro and in a mouse hepatic steatosis model. 🧵

[Scintillon Institute @Scintillon]

Scintillon Center for Resilience to Aging was presented at the Biophysical Society Annual Meeting 26in San Francisco. Learn more about our center's innovations at Scintillon's 1st Innovator Forum in San Diego on March 27th https://t.co/m6oPz2AUNY #aging, #Scintillon, #BPS2026

[Scintillon Institute @Scintillon]

Congratulations to our faculty, Dr. Brian Lawson, for receiving a Healthy Longevity Catalyst Award from the National Academy of Medicine for developing microglia with chimeric antigen receptors as treatment for multiple sclerosis.

https://t.co/MMqPIvkGFV

[Scintillon Institute @Scintillon]

Prof. Guoping Fan of Scintillon has published a new paper in Molecular Cell linking a DNA epigenetic enzyme to mRNA modification and mitochondrial function, with implications for neurodegenerative diseases such as Parkinson’s and Alzheimer’s, and aging.

https://t.co/LRJusMeIz6

[Scintillon Institute @Scintillon]

Panda Express Community Programs https://t.co/afE0ekac8L
Scintillon faculty Drs. Yun Yung and Jiwu Wang serve on the SAB of the Hydrocephalus Association and encourage everyone to support efforts toward finding effective treatments and, ultimately, a cure for hydrocephalus.

[Nature Metabolism @NatMetabolism]

NEWS&VIEWS | X Pan & @VFCracan (@Scintillon, @scrippsresearch)

A new study reveals that in contrast to other #cancer types, translocation renal cell carcinoma is rewired towards an #OXPHOS state, which renders it vulnerable to NADH reductive stress.

https://t.co/kqEWiUtnyL