In #GWAS of >430K people, we found a shared genetic signature across 8 regional chronic pain types - our new paper in @TheJournal_Pain https://t.co/BnMpop1bZH Then, from >1400 biopsychosocial traits we identify causal effects of 488 factors on #pain, incl psych, SES & medical dx
🔬 Exciting breakthrough from the anterior eye lab! PhD student Mark Hoffman found a significant link between severe DE symptoms and chronic pain. This meta-analysis of 3.2M+ patients shows worse symptoms in chronic pain sufferers. @QUT@KatieEd74346911
https://t.co/5j3D3D3U9I
Congratulations to Prof @MicheleSterlin7 on her leadership election as Secretary of the @IASP International Association for the Study of Pain 👏👏
Michele leads the Improving health outcomes after musculoskeletal injury program at RECOVER.
Call out for consumers to contribute to a research project at RECOVER. Dr @ScottFFarrell
is seeking people with lived experience of orthopaedic or multi-trauma (e.g., from a motor vehicle crash), which included a stay in hospital. Learn more: https://t.co/am3wwEBdeu
Original: @ScottFFarrell et al (@RecoverResearch) use UK Biobank to investigate CRP and chronic pain
— ⬆️ CRP assoc. w/ pain independent of biopsychosocial factors
— Possible mechanistic role?
Full: https://t.co/qWl7hxOgei
This is the first of a series of papers revealing "if" and "how" poor sleep drives the development of chronic pain. Enjoy this one and stay tuned for the next.
Poor sleep versus exercise: A duel to decide whether pain resolves or ... https://t.co/0TDk34ZpG5
Do you have neck pain after a recent whiplash injury or neck strain?
If so, please consider volunteering as a participant in our study investigating nerve fibre density in whiplash neck pain. We offer a $50 voucher to reimburse you for time and travel https://t.co/H6TsOmgU9m
Do you suffer neck (whiplash), back pain and/or lower limb pain as a result of a motor vehicle crash? We’re looking for people to partner with us in two projects awarded to Prof @MicheleSterlin7 https://t.co/0K8FvoW274
#ResearchMatters#impact#consumers#neckpain#backpain
@chattyknana@BethDarnall@EurSpineJournal@RecoverResearch Yes, I'd say it is possible that some people with chronic pain in our data had Ehlers Danlos - probably a small portion, given the prevalence of EDS compared with musculoskeletal back and neck pain (or rheum arthritis, fibromyalgia in the widespread group)
Systemic inflammation & chronic pain have a shared genetic basis
Our analysis of chronic spinal + widespread pain #GWAS data reveals genetic correlations with higher CRP, including possible causal links. Published in @EurSpineJournal https://t.co/rqH6d39d0L @RecoverResearch
@chattyknana@BethDarnall@EurSpineJournal@RecoverResearch Sure - our genetic data for people reporting chronic pain conditions came from UK Biobank (GWAS run by our co-authors), while the genetic data for CRP came from Pan UK Biobank and PAGE Consortium (GWAS summary statistics). Thanks for your interest!