Sebastian Scheer

„Back off man, I’m a scientist.“ Epigenetic control of NK cell function @LIH_Luxembourg

[Sebastian Scheer @SebScheer]

@Dr_HeFeng @LIH_Luxembourg @FnrLux @lcsb_uni_lu Congrats! Well done!

[Sebastian Scheer @SebScheer]

@HSudholz @Dr_Nick_Bikes What a pleasure it was! Congrats and well done!

[The Scientist @TheScientistLLC]

NK cells are an important anti-cancer defense, but what happens if they turn into a different cell type?
A new study from @SebScheer @Dr_Nick_Bikes identified a gene without which NK cells turn into a weaker cell type, making them worse at fighting cancer.
https://t.co/4pfB2hcol1

[MalmbergLab @MalmbergLab]

Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." https://t.co/UzENCpFWMv. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED

[Eric Vivier @EricVivier1]

Thrilled to announce the publication of our latest research in Nature Immunology. Joining forces with 20 laboratories in Europe and USA, we identified the three prominent NK cell subsets in human: NK1, NK2, and NK3: https://t.co/VMPTPpiLOV

[Georg Gasteiger @GeorgGasteiger]

Junior Research Group Leader position: Join the Würzburg Infection and Immunology community! https://t.co/zWm8ocDIkE

[Sebastian Scheer @SebScheer]

In our review article, we now assess the current literature and highlight challenges and possibilities around the "conductor" DOT1L and its immunomodulatory functions, that may pave the way for innovative therapeutic approaches.
https://t.co/iirGHuKL4T

[Sebastian Scheer @SebScheer]

After our discovery of DOT1L's role in NK cells https://t.co/miqZV4sQ7q @CellReports, we now published the cherry on top of 7 years of research on DOT1L in the immune system @MonashBDI and @LIH_Luxembourg! @JessicaRunting @DrDThiele @liamckealy https://t.co/iirGHuKL4T @FnrLux

[Sebastian Scheer @SebScheer]

...followed by @liamkealy and @KimLJacobson discovery of DOT1L's importance in B cells. https://t.co/eNISyYkfUc

[Nicholas Huntington @Dr_Nick_Bikes]

New publication from our lab 📣

https://t.co/zapoxSgzkw

We demonstrate that Histone methyltransferase, DOT1L, limits NK cell conversion to ILC1s, a subset that can be observed in tumors in response to TGF-β and is correlated with poor tumor control @HSudholz
@SebScheer

[Dr. Sophie Pilleron @SPilleron]

🖐A new #job opening for a 2-y position as a postdoc in my team!

🔺I'm considering only applications which include responses to the 3 questions I asked in the ad ;)

So, read it before applying.

🙏 Help me circulate that job offer :)

https://t.co/u48BEiFWdN

@LIH_Luxembourg

[Sebastian Scheer @SebScheer]

Back home after a wonderful meeting of Functional Epigenomics in Saarbrücken. Going back to @LIH_Luxembourg with many new inspirations and the excitement that understanding and exploiting epigenetic mechanisms in immune cells will be key to solve many problems in the clinic.

[Sebastian Scheer @SebScheer]

@colbyzaph Big congrats to these exceptional students! However, also a big „well done“ to the PhD „dad“.

[Nature Immunology @NatImmunol]

Huntington and colleagues describe the functions of Ikaros and Aiolos in NK cell development. Read it here: https://t.co/s21mElZ0ji

https://t.co/XF9pwZ4tFU

[Sebastian Scheer @SebScheer]

What Harry says. Well done, team!

[Harrison Sudholz @HSudholz]

Excited to have our paper out in @NatImmunol
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development
https://t.co/5n6YhliBWo

[Qi Zhang @QiZhang85]

I am hiring, please RT🙏🙏

POSTDOC: a molecular biologist to study the mechanism of chromatin modifiers in gene repression. https://t.co/9uMmL9z0Bm
RA & LAB MANAGER: a protein biochemist & to lead the laboratory operations within a brand-new lab.
https://t.co/f3nIjdumtp

[Sebastian Scheer @SebScheer]

En route to #nk2023!

[Sebastian Scheer @SebScheer]

Welcome to the @IEE_Research_Gp team, May Wantz! May will work on the epigenetic regulation of NK cell function as part of our @FnrLux and @FondationCancer funded EPICON project @LIH_Luxembourg. May you do well! 😉

[Monash Research @MonashResearch]

A @MonashBDI study has found that a protective immune feature may be lacking in people with chronic infections caused by parasitic worms, which can help lead to improved #treatments and human vaccines. @MonashCCS #globalhealth

Read it on @MucosalImmunol: https://t.co/ofDYpeHA0m