John Stamos: “I need you to put a video out of just the facts. Don’t make jokes about it, don’t bullshit about it, show video of [Trump], show real facts, show gas prices, take pictures of gas stations if you have to, go in grocery stores if you have to, but make it so undeniably true. Don’t fuck around with jokes, no opinion about it, so I can show my sister and the Republicans in my family and friends. The far-right is not gonna watch you or listen to you or Kimmel or Seth or these podcasters or these great guys, David Pakman’s one of my favorites, they’re not getting to the people that need to see this”
Zach Galifianakis said comedians who have politicians on their podcasts aren’t doing their job if they don’t challenge them.
Zach Galifianakis: Well, other podcasters that have had the president on now, they don't do their court jester. They don't do it. They just, they suck up to them.
Conan O'Brien: Yeah.
Zach Galifianakis: So, the comedians
Conan O'Brien: Yeah.
Zach Galifianakis: that have had, that are podcasters that have had Trump on, that's, they're not doing their job.
Conan O'Brien: Yeah, yeah.
Zach Galifianakis: They're, that's not the job of a comedian. You are to challenge. You are to make uncomfortable. You're not to sit there and fake laugh.
Conan O'Brien: Yep.
In 2010, a team of geneticists drew Ozzy Osbourne's blood to answer one question. He had survived roughly 40 years of drinking and drugs at a level that kills most people. In his own words, he was a medical miracle. So they mapped his whole genome, hunting for the reason.
Only a few hundred people on the planet had been fully sequenced back then. Ozzy landed on a short list that included James Watson, one of the scientists who cracked the structure of DNA. The lab running the analysis compared his code against every genetic study on file at the US National Library of Medicine.
One gene jumped out. ADH4 builds the liver enzyme that breaks down alcohol, and Ozzy carried a version of it never documented before, one that may have let him clear a drink faster than most bodies can. A second oddity sat in a gene that controls how the body handles methamphetamine, parked at a spot that stays fixed across nearly every animal with a backbone. His COMT gene came loaded with both the warrior and the worrier settings for dopamine. Add it up, and his genetic risk of alcohol addiction ran about six times the average. For all that, coffee wrecked him. He was hypersensitive to caffeine.
The final read was blunt. One of the lead scientists summed it up: "We found smoke but no fire." No single Ozzy gene. Nothing in the data explained four decades of survival on its own. His body outlasting the abuse came down to luck and biology too tangled to pin on one line of code.
What finally took him was written somewhere else in the same DNA. In February 2019, after a fall shredded the nerves in his neck, he was diagnosed with a genetic form of Parkinson's his family called PRKN-2, a slow neurological disease with no cure.
By early 2025 he could no longer walk. On July 5 he played his last show seated on a black throne at Villa Park in Birmingham, a short drive from the streets where Black Sabbath formed in 1968. Forty thousand people packed the ground and 5.8 million more watched the livestream. Every pound raised went to Parkinson's research and two children's hospitals.
He died 17 days later, at 76. For years, scientists combed his genome for the thing that made him unbreakable and came up with nothing. The thing that finally broke him was sitting in the same code all along.
All jokes aside though, I think Bill Guerin is under serious, serious pressure to get Larkin
If he can't convince Quinn Hughes to stay, he'll have mortgaged the Wild's prospect pool for nothing