We are open for registration! The EMBO Workshop will take place September 12th to 15th, 2021, as a hybrid event in presence here in Berlin and online.
Find us under: https://t.co/Dze79CpYGu
Check out this report on our meeting: https://t.co/YT144qtQ6i
We thank @J_Cell_Sci for the report and sending an editor and Anita Baillet, @pwoakes and @McMurraylab for writing it. Read on the hybrid conference feeling, new developments in the field and future directions!
Barbara Zieger - Septin deficiency can result platelet secretion defects. Associated with genetic disorders leading to dysplasia (polymicrogyria) and developmental delay, see for example effect of a SEPT5 mutation https://t.co/EIcIq5jotY #EMBOSeptin2021
Like at our last gathering here in 2017 at the beautiful Harnack Haus in Berlin, the last scientific talk is delivered by Barbara Zieger who discovered SEPT5 in humans in the mid 90ies. #EMBOSeptin2021
Rikki Eggert - Lipid constitution of membranes changes significantly throughout cell cycle and cytokinesis. Many cytokinetic regulators are membrane associated, so temporal activity may be associated with specific lipid interactions. https://t.co/fyYkpegQLE #EMBOSeptin2021
Thomas Gronemeyer - Septin 9-EPLIN association revealed in this interactome study.EPLIN over-expression can rescue SEPT9 null mutant phenotypes. Their interplay regulates shape of filopodia, size of focal adhesions, & cellular migration
https://t.co/4OjIyeFkp7 #EMBOSeptin2021
Arnaud Echard - Cytokinesis requires constriction of ESCRT-III filaments on the side of the midbody, where abscission occurs. Septins play roles in the specific localisation dynamics during cell division https://t.co/ZbEPAeKQ5E #EMBOSeptin2021
Arnaud Echard - Remodeling of cytoskeletal elements and cytoplasmic filaments, including septins, microtubules, actin and ESCRT occurs in the late steps of cytokinesis #EMBOSeptin2021 https://t.co/gS32OMhRs8
Michael Krauss - revealing septin phosphatidylinositol phosphate interactions. Septin-PIP interactions requires PIP Kinase1 gamma-isoforms 3 &5. Septin interaction with the microtubule-membrane complex MKLP1 is perturbed upon depletion of PIPK1gamma-i3/i5 #EMBOSeptin2021
Amy Gladfelter - Even small changes in sequence can functionally diversify biophysical properties of septins- as in the ancient gene duplication of Cdc11 in Ashbya. See the preprint @GladfelterLab https://t.co/Jgw2pd6w86 #EMBOSeptin2021
Shoutouts to many past figures in the field that are not actively working on septins anymore: John Pringle, Jeremy Thorner, Daniel Lew, Alfred Wittinghofer, Marian Farkasovsky...