seth rotz

Pediatric Hematologist/Oncologist/BMT @Cleveland Clinic Children's; opinions my own

[Engraft Learning Network @EngraftLN]

Thank you, everyone, for attending our January 2025 design session! We're thrilled to have our project picked and can't wait to see you all this summer. Special shoutout to our Engraft Olympic champions, “You down with A-P-P?”  — stellar teamwork! 🎉

[Akshay Sharma MD @AkshaySharmaMD]

🚨PublicationAlert🚨 How I Treat Sickle Cell Disease with Gene Therapy, published online (https://t.co/GhHdElARNi ) and in print in @BloodJournal
Many thanks to @DrAlexisThompsn @jkw4444 @LakshmananKris7 @shal34982692 @BMTriplettMD and @allistair_2001 for their inputs 🙏

[Jeff Schudel @jsproinsider]

Tom Hamilton, the radio announcer for #Indians / #Guardians games for 35 years and counting on Wednesday was selected by the Baseball Hall Fame for induction in Cooperstown this summer. His emotional reaction is priceless.

[Fred Hutch Cancer Center @fredhutch]

Fred Hutch’s @msorror presents the latest findings on a new health assessment model called CHARM, which helps health care teams predict which patients will survive transplantation. #ASH24 https://t.co/J1CAtW40ZI

[NEJM @NEJM]

Original Article: Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children (AALL1731) https://t.co/IfmgelcOpa

#ASH24 | @ASH_hematology

[Rabi Hanna @RabiHannaMD]

Impressive results about Exa-Cel in TDT from @VertexPharma at # ASH
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD

[Rabi Hanna @RabiHannaMD]

BEACON study initial data @BeamForAll IN #AS24
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis

[Rabi Hanna @RabiHannaMD]

Dr. Rachel Rau presented @COG ALL1731 study at plenary session #ASH24
1- Blina decreased BM relapse significantly across all risk factors including ; hypodyploid , +MRD , Latino ethnicity, etc
2- no change in CNS relapse

[Michelle Monje 🟦 @michelle_monje]

1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵https://t.co/hMe0XYplKz

[Blood Journals Portfolio @BloodPortfolio]

No new safety concerns were identified with daratumumab treatment in children and young adults with B-cell ALL or T-cell ALL/LL. https://t.co/vYYfhcycvC #lymphoidneoplasia

[Rabi Hanna @RabiHannaMD]

Leveraging Oncology Treatments for Vascular Anomalies https://t.co/bF8DFuXB8D via @clevelandclinic

[Rabi Hanna @RabiHannaMD]

Menin inhibitor approved for relapsed or refractory ALL with (KMT2A) translocation in adult and pediatric patients 1 year and older.
FDA approves revumenib for relapsed or refractory acute leukemia with a KMT2A translocation https://t.co/eAT6gHbz8Q

[Rabi Hanna @RabiHannaMD]

Key factors increasing the chance of pregnancy were younger age at HCT, nonmalignant disease, no TBI or dose <8 Gy and RIC/NMA conditioning

@BloodJournal - Hope for motherhood: pregnancy after allogeneic #BMT https://t.co/UnWCQRwQDR

[Engraft Learning Network @EngraftLN]

Engraft was awarded the DENNIS CONFER INNOVATE
AWARD from the NMDP. Congratulations, Engraft! | The ONE Forum 2024 https://t.co/ooX8XHXc0J via @YouTube

[Harry Layton Lesmana, MD @harry_lesmana]

Good morning! Mile 18 is in the book - 6 miles to go ... #The24in24

[Pediatric Hematology/Oncology @CleClinic_PHO]

Congratulations to Dr. Kate Eshleman for receiving the enterprise “Caregiver Philanthropy Award” 🎉

[Rabi Hanna @RabiHannaMD]

I am speechless this afternoon .. Thank you 🙏 #brunswick city and #Medina county for amazing #Trike&Bike @bikeVeloSano to help us fund #ChildhoodCancer #Research @CleClinicKids

[Rabi Hanna @RabiHannaMD]

rain 🌧️ does not stop cancer nor it stop us from getting #together @bikeVeloSano to #Cure #Cancer

[Michael Makris @ProfMakris]

What happens when a virologist develops recurrence of her breast cancer? She injects two viruses into the tumour to shrink it. This is either crazy or genius and I can not decide which. Apparently self experimentation does not require ethics review! https://t.co/GSeSVsduUZ #cancer #breastcancer

[Pat McGann, MD @PTMcGann]

Today is the 1st day of #SickleCellAwarenessMonth

So many awareness angles but let’s not forget that this is arguably the most neglected #GlobalHealth problem

A baby with SCD is born every MINUTE

Awareness is good but we need so much action.

Who’s here for it?