Dr Shanthi Varatharajan

MBBS(Mysore) MHA(Honolulu) MBA Finance(IIU) Grad. Cert. Health Economics(Monash Australia) (MSc Diabetes USW UK)

[Dr Shanthi Varatharajan @ShanthiVaratha2]

Sorry just to remind sugar is not only RM 1 but approved in the STR list including condensed milk, etc 😏😏
@anwaribrahim
https://t.co/0Wi2M6dUvx

[Dr Shanthi Varatharajan @ShanthiVaratha2]

AND SHOULDN'T BE UNDER ' SUMBANGAN KASIH' LIST INCLUDING SUGAR 😔

@anwaribrahim
@GalenCenter
https://t.co/yF5CvFkSsa

[Dr Shanthi Varatharajan @ShanthiVaratha2]

RIGHTLY SAID LGE 👌 MISSED YOU BUT YOU DO COME WITH A SHARP SPEAR INDEED 😁 LIKE MR RAJNI IN TAMIL MOVIES 🤗🤗🤗🤗

https://t.co/YYpRbhzVdT

[Dr Shanthi Varatharajan @ShanthiVaratha2]

Respected Mr Pua 👌👌👌👌👌
https://t.co/75DeLlrT12

[Dr Shanthi Varatharajan @ShanthiVaratha2]

MP Like please look into this issue. It is so rampantly happening that ' youngsters ' in Malaysia are becoming just inhuman. If you visit Thailand if that person is younger than you no matter if you are a senior citizen, they will offer their seat 😊
@anthonyloke

[Dr Shanthi Varatharajan @ShanthiVaratha2]

Now am retired but 35 years ago we doctors worked like that sometimes on call for 15 days, 24 hours but then there was no MMI then 😏 & we worked because WE WANTED EXPERIENCE AS PART& PARCEL OF HAVING A ' DR' TITLE 😊
https://t.co/C4MZelC2dz

[Dr Shanthi Varatharajan @ShanthiVaratha2]

SOUNDS LIKE MORE & MORE OF ' BN BAPAKISM' , MAYBE NEEDS A RED CARPET @ NEXT ELECTION 😡😡😡

@anwaribrahim

https://t.co/tD3syBjyhS

[Dr Shanthi Varatharajan @ShanthiVaratha2]

JUST JOBLESS 🤣🤣🤣

https://t.co/FSQyRb7hWF

[Dr Shanthi Varatharajan @ShanthiVaratha2]

MP LOKE, HAVE YOU TRIED GIVING ' MONKEY ' CHOCOLATE CAKE, SEE WHAT IT DOES 🤣🤣 PLEASE CONTINUE YOUR GOOD JOB 👌👌👌👌
@anwaribrahim

https://t.co/O2s0S7RHnm

[Dr Shanthi Varatharajan @ShanthiVaratha2]

ONLY A ' PONDAN' CAN RECOGNISE ANOTHER SIMILAR ' PONDAN' 🤣 SELALUNY ' ORANG ISLAM' TAK SEBUT PERKATAAN ' PONDAN',🤔 YANG ' CELUP' YAAA 😑😑😑
https://t.co/wakta6rcoh

[Dr Shanthi Varatharajan @ShanthiVaratha2]

CAN SOMEONE PLEASE EXPLAIN THIS REASONING, ' POLITICAL CANDIDATE WHO HAS BEEN SENT A RED CARPET HAS BECOME THE ' SENIOR POLITICS ADVISOR TO THE PM ELECTED BY RAKYAT 🤔 IS HE THE RIGHT PERSON WHEN ' FAILED EXAM?' 😑😑😑😑
@anwaribrahim
@rafiziramli
https://t.co/gPa01iYeAz

[Dr Shanthi Varatharajan @ShanthiVaratha2]

MP, ANYBODY VOTING FOR UMNO'/BN IS ' GETTING A BURIAL DUG FOR THEIR GENERATION ' IF THEY HAVEN'T LEARNT A LESSON 😑😑😑

https://t.co/BH3NNdW0OK

[Dr Shanthi Varatharajan @ShanthiVaratha2]

https://t.co/mAsl6FxLnc

[IJDDC @ijddcofficial]

Dr @purvi_chawla in conversation with Dr Vaishali Deshmukh on the RSSDI Position Statement: Mind–Body Medicine in Diabetes—exploring evidence-based, holistic approaches to diabetes care.

▶️ Watch here: https://t.co/GmglsOppwS

#IJDDCPodcast #MindBodyMedicine #RSSDI #DiabetesCare

[Dr Shanthi Varatharajan @ShanthiVaratha2]

HOW FAST FOOD CAN DISAPPEAR SO FAST 🤔 SO ARE WE ALSO INVITING 'DIABETES/ OBESITY/HYPERTENSION TO OUR ENGORGED PUBLIC HEALTHCARE CLINICS 😑😑😑😑
@anwaribrahim
@MOFmalaysia
@DrDzul

https://t.co/tFlmxqsSAY

[CME INDIA @CMEINDIA1]

Eat by the Clock, Protect the Brain: Mitochondrial Timing for Vascular Longevity

Time-Restricted Feeding, Mitochondria, and the Aging Cerebrovascular Unit

🔹 Cerebrovascular aging is fundamentally mitochondrial. With advancing age, endothelial mitochondria develop redox imbalance, impaired mitophagy, and bioenergetic inefficiency — driving oxidative stress, endothelial senescence, and dysfunction of the neurovascular unit.

🔹 Endothelial failure precedes cognitive decline. Loss of nitric oxide signaling, disrupted neurovascular coupling (NVC), and weakening of the blood–brain barrier (BBB) reduce cerebral perfusion and metabolic flexibility — mechanistic substrates for vascular cognitive impairment.

🔹 Microvascular vulnerability is amplified in the brain. Neural tissue operates at extreme metabolic demand; even subtle endothelial mitochondrial dysfunction translates into impaired synaptic energy delivery and neuroinflammation.

🔹 Time-restricted feeding (TRF/TRE) is a circadian metabolic reset. By aligning feeding windows with endogenous clocks — without calorie restriction — TRF restores mitochondrial efficiency and activates adaptive nutrient-sensing pathways.

🔹 Key molecular switches are engaged. TRF enhances AMPK and SIRT1 signaling, suppresses mTOR overactivity, improves mitophagy, reduces mitochondrial fragmentation, and promotes metabolic switching toward ketone utilization — a cleaner neuronal fuel.

🔹 Endothelial resilience improves. Restored mitochondrial signaling supports nitric oxide bioavailability, stabilizes BBB integrity, and preserves NVC — protecting the vascular interface that sustains cognition.

🔹 Metabolic timing influences vascular aging biology. TRF operates upstream of traditional risk-factor modification by directly targeting mitochondrial and endothelial repair programs.

🔹 Clinical implication: Circadian-aligned eating patterns may represent a practical, non-pharmacologic strategy to slow cerebrovascular aging and mitigate vascular contributions to cognitive decline.

🔹 Translational insight: Vascular healthspan and brain healthspan share mitochondrial governance — dietary timing is emerging as a modifiable regulator of this axis.

Source: Aging Cell — mechanistic review on mitochondrial dysfunction, endothelial aging, and time-restricted feeding in cerebrovascular health.
Link: https://t.co/lWWOYYihd4

[Dr Shanthi Varatharajan @ShanthiVaratha2]

DON'T THINK IT'S GOING TO IMPROVE WITH ' FROZEN FOOD' WHICH IS SOON TO BE APPROVED 😑 INSTEAD APPROVE FRESH VEGETABLES/FRUITS 🙏🙏🙏

https://t.co/0hUeakqksr

[Dr Shanthi Varatharajan @ShanthiVaratha2]

WIFE NOT HAPPY LAH 😝 TOLD HIM ' NO INCOMING INCOME DON'T COME HOME' 😝😝😝😝😝
https://t.co/1mVukviH0R

[Dr Shanthi Varatharajan @ShanthiVaratha2]

👌👌👌👌
https://t.co/qN5aXKwTiU

[Dr Shanthi Varatharajan @ShanthiVaratha2]

👌👌👌