Shutong Du

[OOIR @ObserveIR]

Trending in #Medicine:
https://t.co/w6hCoGTNKd

1) Rape-Related Pregnancies in the 14 US States With Total Abortion Bans (@JAMAInternalMed)

2) Microplastics & Nanoplastics in Atheromas and Cardiovascular Events (@NEJM)

3) Ultra-processed food exposure & adverse health outcomes (@BMJ_Latest)

4) Cognition & Memory after Covid-19 in a Large Community Sample (@NEJM)

5) Worldwide trends in underweight & obesity, 1990-2022 (@TheLancet)

[Shutong Du @ShutongDu]

Q: What do we know about GLP-1 weight loss effects on body composition?
A.: Potential concerns for lean muscle mass loss (e.g. sarcopenia), more research is needed. Types of physical activity combined with pharmacotherapy are important (e.g., resistance training).

[Amelia Wallace @ASWallaceEpi]

Starting the question session: @thoughts_by_MDG asking about how medical schools should approach teaching students about obesity treatment. A: start clinical work early and directly address the potential for bias.

[Shutong Du @ShutongDu]

Lifestyle interventions should still be considered the foundation of first-line therapy for obesity.

[Shutong Du @ShutongDu]

Rebuttal from Dr. Molly Baldwin Conroy: preliminary study shows a combination of lifestyle and pharmacotherapy treatment is better than pharmacotherapy alone in maintaining weight loss. #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Shutong Du @ShutongDu]

Rebuttal from Dr. Molly Baldwin Conroy: preliminary study shows a combination of lifestyle and pharmacotherapy treatment is better than pharmacotherapy alone in maintaining weight loss. #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Amelia Wallace @ASWallaceEpi]

Follow along with @ShutongDu and I as we live tweet the @ASPCardio debate: Obesity First Line Therapy: Pharmacotherapy vs. Lifestyle Medicine!

[Amelia Wallace @ASWallaceEpi]

Final point: there are already disparities in prescribing of pharmacotherapy, which could exacerbate disparities in outcomes #EPILifestyle24

[Shutong Du @ShutongDu]

GLP-1 RAs health benefits are more than just weight reduction. And its mental health side effects are unclear. #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Shutong Du @ShutongDu]

Evidence is accumulating for use of GLP1-RA for obesity and CVD treatment #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Shutong Du @ShutongDu]

Also "DPP-based lifestyle interventions are readily scalable and exportable with the potential for substantial clinical and public health impact"

[Amelia Wallace @ASWallaceEpi]

A reminder of the landmark DPP trial, which showed that a lifestyle intervention was better at reducing diabetes risk than metformin pharmacotherapy. #EPILifestyle24

[Shutong Du @ShutongDu]

Dr. Molly Baldwin Conroy: lifestyle and physical activity changes are still relevant topics for every patient and there are many opportunities in a primary care setting for lifestyle intervention. #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Amelia Wallace @ASWallaceEpi]

Follow along with @ShutongDu and I as we live tweet the @ASPCardio debate: Obesity First Line Therapy: Pharmacotherapy vs. Lifestyle Medicine!

[Shutong Du @ShutongDu]

Evidence is accumulating for use of GLP1-RA for obesity and CVD treatment #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Amelia Wallace @ASWallaceEpi]

Follow along with @ShutongDu and I as we live tweet the @ASPCardio debate: Obesity First Line Therapy: Pharmacotherapy vs. Lifestyle Medicine!

[Shutong Du @ShutongDu]

Dr. Powell-Wiley gave us two reasons why Pharmacotherapy should be prioritized: 1. Achieving and maintaining weight loss is challenging. 2. Lifestyle intervention is limited for those who are mostly affected by obesity #EPILifestyle24 #JAHAMeetingReport #AHAJournals @JAHA_AHA

[Amelia Wallace @ASWallaceEpi]

Follow along with @ShutongDu and I as we live tweet the @ASPCardio debate: Obesity First Line Therapy: Pharmacotherapy vs. Lifestyle Medicine!

[Tiange Liu, PhD, MBBS @tiangeliu_]

Dr.@MingyuZhang_ gave a fantastic talk on the long-lasting adverse effects of prenatal exposures to “forever chemicals” #PFAS on adiposity in childhood. This important work was done in @ProjectViva_DPM
#EPILifestyle23

[Yingan(Lianne) Chen @LianneChen97]

Tiange @tiangeliu_ just presented their exciting finding that Infant Gut Microbiome Is Associated with Child Blood Pressure at Age 3 and 6 years in A Danish Birth Cohort. The association can be modified by breastfeeding duration.
#EPILifestyle23 #JAHA_MeetingReport @JAHA_AHA

[Yingan(Lianne) Chen @LianneChen97]

Dr. Siwen Wang is giving a presentation on"Adherence to Preconception Healthy Lifestyle and Adverse Pregnancy Outcomes". They found Adherence to six healthy lifestyles is associated with lower risk of APO. #EPILifestyle23 @JAHA_AHA @AHAMeetings @AHAScience #AHAJournals

[Shutong Du @ShutongDu]

#EPILifesyle23 Dr. Sara Bleich gave us an excellent keynote lecture on the current nutrition policy in the U.S.! She introduced us to the many emerging opportunities to contribute to policy implementation and emphasized the value of clear communication. @American_Heart @DrBleich

[Shutong Du @ShutongDu]

#EPILifesyle23 Dr. Josiemer Mattei gave us an important keynote lecture on implementing evidence-based diet programs for minority groups, specifically her research on the cardiovascular health impacts of a Puerto Rico-optimized Mediterranean-like diet. @American_Heart

[Amelia Wallace @ASWallaceEpi]

Next up is Dr. Josiemer Mattei giving us examples of implementation of heart health science in the real world

[Shutong Du @ShutongDu]

#EPILifesyle23 Dr. Crystal Wiley Cené gave us a fun and informative keynote lecture on distinguishing, evaluating, and conducting implementation research, as well as the importance of leveraging implementation science among marginalized populations. @DrCrystalCene @AHAMeetings

[Shutong Du @ShutongDu]

Over 600 poster presentations, 13 moderated poster sessions, and daily networking roundtable session are happening at the #EPILifestyle23

[Amelia Wallace @ASWallaceEpi]

@AHAScience @AHAMeetings Cardiovascular disease is still a leading cause of death in the US. Clinicians and researchers should move toward framing CVD as a life-long disease -- not "cured" by stents and surgeries

[Shutong Du @ShutongDu]

#EPILifestyle23 opening session is today! Dr. Michelle A. Albert is giving the presidential remarks on implementing scientific knowledge for healthy hearts. @AHAMeetings @American_Heart