Silberstein Lab

We are a hematopoiesis lab @FredHutch investigating the behavior of healthy and malignant hematopoietic stem cells

[Silberstein Lab @Silberstein_Lab]

@bikohcello Oh no.... let's hope it changes when I come to visit!

[Hematopoiesis News @Hema_News]

This @NatureGenet study screened for somatic mutations in healthy aged individuals, identifying expanded HSC clones accessible for lineage tracing of all major blood cell lineages. 🩸

✅ Check it out!
https://t.co/qkCjoQ63Rw

[Jeevisha Bajaj @Jeevisha_Bajaj]

Thrilled to share our work on the role of taurine in myeloid leukemia progression in @nature today! https://t.co/V4GCWkK6jT

[Silberstein Lab @Silberstein_Lab]

Thank you to the wonderfully talented Rioka Hayama https://t.co/omgBsOBtCM for blending the senior author’s two passions - classical music and biology - to capture the essence of our paper https://t.co/bwjcAMBq93, and to Nature Aging editors for choosing it as the cover art.

[Silberstein Lab @Silberstein_Lab]

@LabAgarwal Thank you very much, Anupriya!

[Silberstein Lab @Silberstein_Lab]

How do hematopoietic stem cells resist inflammatory damage and do not age prematurely? Turns out that Semaphorin 4A-producing neutrophils come to rescue, as we report in our first paper, out in Nature Aging https://t.co/ovVBWM9NCF. Cudos to 36 coauthors, reviewers and NA editors!

[Silberstein Lab @Silberstein_Lab]

@TakizawaLab Sounds like a very good reason to come, will try!

[Silberstein Lab @Silberstein_Lab]

@SanjayPatelMD Thank you, Sanjay!

[Silberstein Lab @Silberstein_Lab]

@PapapetrouMDPhD Thank you, Eirini - took a few years....

[Silberstein Lab @Silberstein_Lab]

@TakizawaLab Thank you - hope we can discuss these data in person soon!

[Silberstein Lab @Silberstein_Lab]

@DrMonicaGuzman Thanks so much, Monica! Look forward to brainstorming more about this!

[Silberstein Lab @Silberstein_Lab]

@RohanKhadilkarr Thank you - very glad to hear!

[Silberstein Lab @Silberstein_Lab]

@LabWaggoner @NatureAging thank you for spreading the word about our work!

[Itai Yanai @ItaiYanai]

Out today in @NatureBiotech! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. https://t.co/Xw7VpKHot2…
@MartinJLercher

[Silberstein Lab @Silberstein_Lab]

We are looking for a technician and a post-doc. If you know anyone who's interested in pre-leukemia/inflammation/the niche and enjoy exploring nature, please ask to RT or email [email protected]. Thank you!

[Silberstein Lab @Silberstein_Lab]

Truly wonderful to reconnect with old colleagues and meet new ones at Mol Haematopoiesis meeting in London. Thank you for the opportunity to hear tremendous speakers and present our data, and to Doug Higgs for his inspirational advice "to enjoy every day of doing science".

[Silberstein Lab @Silberstein_Lab]

We are looking for a new Technician colleague to study the biology of HSC and their niches in inflammation, pre-leukemia and aging. Will fully support anyone who is interested in becoming a leader for their project. DM/email [email protected] to explore this opportunity.

[Silberstein Lab @Silberstein_Lab]

We currently have two post-doctoral positions for those interested in studying how niche factors can be converted into drugs to prevent leukemic evolution and inflammation-induced HSC damage. Please DM or email [email protected] to find out more!

[Silberstein Lab @Silberstein_Lab]

@CterminiPhD Thank you, Tina!

[Silberstein Lab @Silberstein_Lab]

Grateful and honored to have our MDS work now supported by @EdwardPEvansFdn
Discovery grant! Thank you to @edie_crosse and others in the @Silberstein_lab for input and preliminary data. Look forward to working with @StanleyCLee, @JShendure and @SteidlUli on this exciting project!