Simone Mattei

Cryo-EM aficionado that used tomography and subtomogram averaging to close the gap between HIV cores and Christmas trees.

[Simone Mattei @SimoneMattei19]

Upside down! Our latest in situ cryo-ET work shows how cytosolic ribosomes bind mitochondria via their SSU as an adaptive response to cellular stress. A great collaboration with @jomaa_lab! #TeamTomo @embl @EmblImaging
https://t.co/9qZTH1mnP8

[Ahmad Jomaa @jomaa_lab]

Want to know what happens when mitochondria get stressed? Check our latest pre-print with @SimoneMattei19 lab on how mitochondria tether hibernating ribosomes as an adaptive response to glucose depletion in yeast!
https://t.co/G7Ku5KKIsX
#teamtomo #cryoEM #ribosomes #mitochondria

[Ahmad Jomaa @jomaa_lab]

Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group @UVA and @simonemattei @EMBLHeidelberg
https://t.co/YKDCLFowvC

[EMBL @embl]

Despite its name, SNOR, a newly discovered protein, is hardly asleep on the job.

EMBL researchers’ newest technologies allowed them to discover this tiny protein with a big role that awakens cells from dormancy to restart protein synthesis.

https://t.co/XkvQIWBLLi

[Ahmad Jomaa @jomaa_lab]

Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: https://t.co/4WJcgdgRY7

[Simone Mattei @SimoneMattei19]

Grateful to the Boehringer Ingelheim Stiftung for their renewed support. Their commitment empowers us to further advance our mission: enabling broad access to state-of-the-art imaging technologies for the scientific community

[EMBL @embl]

Boehringer Ingelheim Stiftung has committed €7 million to EMBL’s Imaging Centre.

That means more opportunities to create groundbreaking, next-gen imaging technologies & provide necessary support to European life scientists.

https://t.co/DYjHL3rxEH

[Ahmad Jomaa @jomaa_lab]

Check out our latest preprint with Qi lab on the structure and disease physiology of the human ERAD complex. Outstanding work by Leo, a cell physiologist whom we successfully tempted into structural biology! Preprint: https://t.co/ebaTAJdFNN

[Simone Mattei @SimoneMattei19]

Thanks to @instructhub funding the @EmblImaging Centre is able to offer an advanced hands-on workshop on cryo-FIB-SEM methods. This is a great opportunity to exchange knowledge with our fantastic cryo-CLEM specialists! Apply here before May 12th: https://t.co/nWQSAPzX8C

[EMBL Imaging Centre @EmblImaging]

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📣 Apply now: @instructhub INSTRUCT-ERIC hands-on #workshop: Advanced cryo-FIB-SEM methods on 21-25 July 2025. Limited to 12 participants. Apply before 12th May 2025.

[EMBL @embl]

The @ChanZuckerberg Initiative is funding two EMBL projects, coordinated by @EmblImaging, to support imaging technologies development. 🔬

The projects will integrate advanced microscopy techniques to improve the understanding of biological systems.

https://t.co/LDxtq74MNA

[EMBL @embl]

Science meets art at the EMBL Imaging Centre! 🔬🎨

Several scientists shared their experience as users of this facility and explain why it is a unique place to turn your research into stunning, informative images.

Read the full article here 👉 https://t.co/9U7906MdMM

[Yura Bykov @yurabykoff]

Niels Weidemann edited a volume of Methods in Enzymology on mitochondrial import. I was honoured to write a review about yeast genetics together with Maya Schuldiner! I hope it will be useful.
https://t.co/Owz7FG2BDE

[Simone Mattei @SimoneMattei19]

It’s great to see our hibernating ribosomes story finally out @NatureComms! Thanks to @jomaa_lab @MedicineUVA and all @EMBL and @EmblImaging people that supported this project. https://t.co/ofaFVodExn

[Ahmad Jomaa @jomaa_lab]

Happy to share our little discovery with @SimoneMattei19 team on how ribosomes hibernate upside down on mitochondria during cellular stress is now out @NatureComms! A collaboration between @medicineUVA, @EMBL, @EmblImaging, MEMC. Congrats to all authors! https://t.co/DE6eAamt5I

[Chan Zuckerberg Initiative @ChanZuckerberg]

What if we could peer inside a living organism + watch biology unfold in real-time...down to the microscopic level? 🔬 Researchers like @Prevedel_Lab are working to make this ultra-high res deep tissue imaging possible!

[Simone Mattei @SimoneMattei19]

Fantastic news! All the best for this scientific journey Yura!

[Yura Bykov @yurabykoff]

I am very honored to get the @ERC_Research StG and looking forward to the next 5 years of exciting research. I am grateful to my mentors and colleagues who helped me along the way!
https://t.co/zEHiPFU1jk

[EMBL Imaging Centre @EmblImaging]

Registration now to the @EMBL Imaging Centre User Symposium 2024!

Don't miss this opportunity, especially:
✅ limited workshop by @LeicaMicro and @zeiss_micro
✅ 10 speakers from different expertises

More info & registration: https://t.co/slXbbDAvFS

#ImagingTechnology

[Jana Helsen @HelsenJana]

How do karyotypes evolve? Turns out an intracellular tug of war within the metaphase spindle sets the limits for chromosome number evolution. Excited to see our study out today in @NatureCellBio https://t.co/z0zeOTtjBd  1/9

[Ori Avinoam @Avinoam_lab]

This is the one 👇🏻

[Stefan Terjung🇪🇺 @StefanTerjung]

We are looking for an experienced light microscopy specialist to support the Advanced Light Microscopy Facility @embl Heidelberg: https://t.co/HjIiZoc1Ph - closing date 5 August 2024
@EuLiMI1 @EuroBioImaging @GerBI_GMB @Fr_BioImaging @GlobalBioImage @BioImagingUK

[EMBL Imaging Centre @EmblImaging]

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Don’t miss the opportunity to join us at the @EMBL Imaging Centre User Symposium 2024 will be held on 17 to 18 October 2024. Do not miss the deadlines and secure the limited spot. #imaging #CryoEM #superresolution #microscopy.

Read more&register: https://t.co/JQNF8QqJ6X

[Simone Mattei @SimoneMattei19]

This is a great opportunity! 👇🏻

[Claudia Alen Amaro @claudialenamaro]

We start the second day of @iNEXT_Discovery final meeting with a talk from one of @instructhub facility @EMBLGrenoble
#EasyGrid a versatile platform from #cryoEM sample preparation developed by @PappTeam in collaboration with @EMBLHeidelberg @SimoneMattei19

[Stefan Pfeffer @PfefferCryoLab]

We have two open PhD positions to explore structures of ribosomes and gamma-tubulin complexes using cryo-EM approaches here in our group @ZmbhH @UniHeidelberg.
Please apply via the Heidelberg Biosciences International Graduate School @HBIGS_HD: https://t.co/cJZCFXlssa