Simone Augustinus

👩🏼‍⚕️Young medical doctor 🔥 Pancreatic researcher 💫 Running, cycling, skiing, fieldhockey

[Simone Augustinus @Simone_Aug]

🚨 Significant interrater variability in scoring the ASA classification for patients undergoing HPB surgery

📊 Survey 1283 surgeons/anaesthesiologists
🌎 55 countries
‼️ Additional guidance is needed, until then more objective measurements should be used for case-mix adjustment

[BJS Open @BjsOpen]

Inter-rater variability for the American Society of Anesthesiologists classification in patients undergoing hepato-pancreato-biliary surgery (MILESTONE-2): international survey among surgeons and anaesthesiologists
➡️https://t.co/U00As2bbKm

This is an international survey and case-vignette study including 1283 participants from 55 countries. Interrater variability regarding the ASA classification in patients undergoing HPB surgery was observed, which may impact perioperative strategy. Additional guidance to classify patients according to ASA is urgently needed. Until then, more objective measurements should be considered for case-mix adjustment within research.

👏👏👏@Simone_Aug, Jasper P Sijberden, Matthanja Bieze, Vandana Agarwal, Luca A Aldrighetti, Adnan Alseidi, Francisco C Bonofiglio, Kevin C P Conlon, Katia Donadello, Joris Erdmann, Cristina Ferrone, Michael Guertin, Ronald Harter, Maria E Franceschetti, Guiseppe K Fusai, Bas Groot Koerkamp, Thilo Hackert, Jin-Young Jang, Thomas Kander, Tobias Keck, Dominik Krzanicki, Ho-Jin Lee, Keith Lewis, Giuseppe Natalini, Carla Nau, Timothy M Pawlik, Henry A Pitt, Rafaella Reineke, Roberto Salvia, Eduardo de Santibanes, Shailesh V Shrikhande, Martin Smith, Attila Szijarto, Bobby Tingstedt, Alice C Wei, John Windsor, @Abuhilal9Abu, Manuel Pardo, Markus W Hollmann, @MarcBesselink for the MILESTONE Study Group

#SoMe4Surgery #MedTwitter #SurgEd #Surgery @BJSAcademy @BJSurgery @young_bjs @juliomayol @JJEarnshaw @OUPMedicine #some4hpb #some4tpl @hpb_so #PancreaticCancer #PancreaticSurgery @YouppiePancreas @German_PancClub @surgery_hps #PancreasClub2023 @PancreasClub @DPCG_official @pancreatitis_nl @PanCAN #PanCANawareness @EurPancClub @P_C_E_ @dice_europe

[Simone Augustinus @Simone_Aug]

Full tekst: https://t.co/PpgmLtCjX3

[Simone Augustinus @Simone_Aug]

In @JNCCN our nationwide study on quality of life in patients with locally advanced PDAC🇳🇱

⭐️QoL remains stable over time, regardless of receiving treatment (89%)
‼️Symptoms significantly deteriorate and deserve attention

➡️Use in shared decision making https://t.co/83ezNBGWgU

[JAMA Surgery @JAMASurgery]

Only 10% of recommendations in surgical clinical practice guidelines are supported by high quality evidence. https://t.co/6BwphH3qaF

[Giovanni Marchegiani @Gio_Marchegiani]

(Let’s keep using this social in the best possible way … ) 🫢

🟠 Recurrence after PDAC resection is sadly a fact

🔵 @EAHPBA study on 333 pts reveals routine imaging in post op 👍 vs. symptomatic FU

💡Prompt access chemo = better survival

https://t.co/cbwMEr2qrG

[Marc Besselink @MarcBesselink]

How big are the differences in the use, outcome Lap/Robot 🤖 #Whipple between 4 registries 🇺🇸/🇨🇦, 🇩🇪, 🇳🇱, 🇸🇪? #GAPASURG

▶️ Very large differences among 3328 pts in the use of MIPD: 🇺🇸🇨🇦7%, 🇩🇪4%, 🇳🇱17%, 🇸🇪0.1% and rapidly changing still

▶️in-hospital/30-day mortality 🇺🇸🇨🇦2%, 🇩🇪7%, 🇳🇱4%.

▶️ https://t.co/3v5jo2vthk

[Simone Augustinus @Simone_Aug]

💡LIDOPAN study: multicenter pilot trial

💉 IV lidocaine for patients in pain with PDAC and CP
👥30 patients, NRS >4

📈 No overall clinically relevant pain reduction day 1
🤩 31% positive effect, lasted op to a month

https://t.co/uNzbw4WAI9

@ACG_CTG

[Thomas Stoop @TFStoop]

In @AnnSurgOncol, #GAPASURG study 🇺🇸🇨🇦🇩🇪🇳🇱🇸🇪 with 2924 #PancreaticCancer patients on DP-PVR vs. standard DP.

DP-PVR 🟰
⚠️associated with ⬆️ in-hospital/30d major morbidity (24% vs. 18%);

⬆️CR-PPH (10% vs. 3%)🩸;

✅NOT associated with in-hospital/30d mortality (1.7% vs. 1.2%).

[Simone Augustinus @Simone_Aug]

Very honored to give the @YouppiePancreas award 🏆presentation at #EPC2024: looking beyond trial results in pancreatic research ⭐️

Key points:
1️⃣ Improve international comparison
2️⃣ Use of alternative RCT designs
3️⃣ Importance of implementation

@DPCG_official

[YOUPPIE Pancreas @YouppiePancreas]

🗣️TOMORROW THURSDAY JUNE 27th‼️

🔥1️⃣0️⃣:0️⃣0️⃣🔥@ #EPC2024

The amazing💥 YOUPPIE awardees @Simone_Aug and @ThomasHankMD will give their talks🏆

👉 BE THERE 💜💜💜!!!!!!!!!!!!!!

[Marc Besselink @MarcBesselink]

How do the use and outcome of Minimally invasive Whipple compare between 🇺🇸 🇳🇱🇩🇪🇸🇪? https://t.co/GOOmnyV7pm @nine_degraaf

Big differences! Highest use in 🇳🇱 17%, lowest in 🇸🇪 0.1%.

Conversion rates lowest in 🇳🇱, especially robot 9%. #IHPBA24

[Marc Besselink @MarcBesselink]

Two lectures, one message: input of female hpb surgeons is increasing @IHPBA @EAHPBA @AHPBA #APHPBA: but not enough!

Bill Jarnagin, in his presidential address & @MinterWiscSurg:
➡️We need female presidents⬅️
#LetsDoIt

@@iisifrigerio @HalletJulie @HoggNDMD @AisteGulla @carlijnbuis @mary_dillhoff @MissJanetKung @Surgerygirl8 @asuhool @JonyvanHilst @TessvRamshorst @nine_degraaf @TEHendriks @julia_menso @LC_Leeuwenburgh

[Philipp Kron @KronPhilipp]

It’s a wrap. #europeansurgicalassociation
Fantastic start with the next generation of surgeon scientists @Simone_Aug @MarkarSheraz Fantastic presentations over the days! @MA__Schneider and an impressive Gala Dinner!
@shahidfarid @profpeterlodge
@uktuebingen

[YOUPPIE Pancreas @YouppiePancreas]

Last day - Spread the word 💜💜👇👇‼️

@AnaDugic @LumirKunovsky @SN_gastro @CSKnoph @SimonSirtl @Simone_Aug @ThomasHankMD @Lguilabert1 @HughesDLlwyd @vasyb @mstotty88

[Simone Augustinus @Simone_Aug]

Kick off next generation ESA 🇪🇺

👨🏾‍⚕️ Do’s and don’ts during surgical fellowships @MarkarSheraz
💵 How to obtain funding for research @BrunsChristiane
⭐️ The road to academic succes #PiereAlainClavien

➡️ All highlighting importance of: mentorship, diversity and perseverance!

[Simone Augustinus @Simone_Aug]

@mstotty88 @YouppiePancreas @DPCG_official Looking forward to it! 🙏🏻

[Simone Augustinus @Simone_Aug]

Very gratefull for winning the YOUPPIE award 🌟

Looking very much forward to presenting at the EPC & meeting all new @YouppiePancreas friends 🙏

➡️Towards many more future projects with o.a. @DPCG_official and #Pancreas2000 🇪🇺

[YOUPPIE Pancreas @YouppiePancreas]

🔥🎉YOUPPIE AWARDEES 2️⃣0️⃣2️⃣4️⃣🎉🔥

We congratulate @Simone_Aug and @ThomasHankMD who, in a very tough competition, receive the YOUPPIE awards of 2024 👏🏆!!!

Thank you to all the contestants 🙏💜

Hear our winners talk about their amazing research at #EPC2024 in🇪🇸 June 2️⃣7️⃣th

[JAMA Surgery @JAMASurgery]

In this randomized clinical trial, implementation of 5 best practices in pancreatic cancer care did not improve 1-year survival and quality of life. Findings highlight the need for more personalized treatment options. https://t.co/5tUrDErird @MarcBesselink

[Simone Augustinus @Simone_Aug]

Are you an aspiring young academic surgeon? ⭐️

European Surgical Association (ESA) mentorship program deadline April 1st 🇪🇺

&

ESA Next Generation meeting before the conference (incl networking 🙏)!

More information:
https://t.co/O0r2d5Q5l0

#ESA #Leeds #May2024 #BeThere

[JAMA Surgery @JAMASurgery]

In this randomized clinical trial, implementation of 5 best practices in pancreatic cancer care did not improve 1-year survival and quality of life. Findings highlight the need for more personalized treatment options. https://t.co/VRQ1BpBQcC @MarcBesselink