Thomas Stoop

MD, PhD candidate HPB Surgery Amsterdam UMC 🇳🇱| Former Research Fellow Karolinska University Hospital 🇸🇪 & University of Colorado 🇺🇸

[Thomas Stoop @TFStoop]

Published in @TheLancet, our review on #PancreaticCancer
📎Epidemiology🌎
📎Pathogenesis🔬
📎Risk factors & surveillance🕵️
📎Diagnostics🩺
📎Treatment💊
📎Future directions🔍
… by @ammar_asrar, @ObaAtsushi, T. Seufferlein, JW Wilmink, @BasGrootKoerkam & @MarcBesselink

[NEJM @NEJM]

Original Article: Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer (phase 3 RASolute 302 trial) https://t.co/y4G27hfORg

#ASCO26 | @ASCO

[Marc Besselink @MarcBesselink]

#HoraEst 🎓 @IngmarFRompen today @UvA_Amsterdam “Extended indications for #pancreatic #surgery (#promotie). Well done Ingmar!!

➡️ https://t.co/PP3AWsqBwk

🎯Amazing thesis including 14 chapters, all published, including 9x(!!) @AnnalsofSurgery. Thanks to all 99 co-authors from 🇩🇪🇺🇸🇳🇱 🇮🇹🇳🇴🇸🇪🇫🇮🇩🇰🇬🇧🇯🇵

✅ Wonderful collaborative PhD team @MarcBesselink @cw_michalski 🇩🇪 @cwolfga2 🇺🇸 @ammar_asrar 🇺🇸 @DPCG_official

Thanks to the excellent committee including @Gio_Marchegiani @TFStoop @i_verpalen @HenrikNien

[Marc Besselink @MarcBesselink]

#PELICAN randomized trial @DPCG_official 🇳🇱 published @JAMANetworkOpen:

❓Can #RFA following induction chemoth improve survival vs chemoth only in 188 pts with nonprogressive but nonoperable locally advanced #pancreaticcancer (#LAPC)?

🔑 No. Moreover QoL ⤵️ 👀

#PREOPANC4 coming up.

▶️ https://t.co/Gjrsnxlap0

[Marc Besselink @MarcBesselink]

#Horaest 🎓 @TFStoop #CumLaude PhD ceremony today 🙌 (best 3% thesis)
“A #paradigm #shift in localized #PancreaticCancer” @DPCG_official, @UvA_Amsterdam

⏩️ https://t.co/jNoVkQwpE6

✅#PREOPANC4 nationwide 🇳🇱 implementation LAPC surgery
✅International, national studies on #neoadjuvant #adjuvant treatment #quality of life and #surgery in #PancreaticCancer
✅543 pages, 19 chapters (incl @TheLancet), 150 co-authors, 20 countries, 286 impact factor points; median 10+.

Thank you @sparrelid🇸🇪 for the excellent discussion!

[CUpancreas @CUpancreas]

Proud to have Dr.Oba in our Division! Dive into the story below.

[Marc Besselink @MarcBesselink]

Bihormonal Artificial Pancreas after #Total #Pancreatectomy?
✅Protocol #PANORAMA trial published @BjsOpen @DPCG_official 🇳🇱 >> results coming up….

⏩️ https://t.co/PjhhEFmcLj

[Thomas Stoop @TFStoop]

@CUpancreas @CUDeptSurg @RichSchulickMD @chiaro_del Thank you @RichSchulickMD. It has been an honor working for you at @CUAnschutz, inspired by your expertise, leadership, and kindness 🙏🏻.

[CUpancreas @CUpancreas]

We extend our sincerest gratitude to Dr. Schulick for his exceptional service as Chair of the @CUDeptSurg, during which he guided significant growth and innovation. His vision and dedication leave an extraordinary impact. #ImproveEveryLife @RichSchulickMD @chiaro_del

[Marc Besselink @MarcBesselink]

#HoraEst today for @annegehrels om #PancreaticCancer with
@DPCG_official 🇳🇱 @UvA_Amsterdam

⏩️ https://t.co/OkVnQkROVT

✅#NAPAN trial: Second-line liposomal irinotecan plus S-1 vs. liposomal irinotecan plus 5-fluorouracil in metastatic pancreatic cancer: the phase I/II randomized trial
✅#PREOPANC5 trial protocol: Neoadjuvant mFOLFIRINOX, pembro, and SBRT for borderl resect pancreatic cancer: multicenter phase 1/2 single-arm trial

Excellent multidisciplinary collaboration Hanneke Wilmink, Hanneke van Laarhoven an in the committe Davide Melisi 🇮🇹

[Marc Besselink @MarcBesselink]

#HoraEst today for @MichielFrancken @amsterdamumc @UvA_Amsterdam

“Interventions for pancreatic diseases”
✅ #POINTER trial costs
✅#PICUS2 cholecystectomy for idiopathic pancreatitis, trial design
✅#PANACOTTA (obot vs open PJ chronic pancreatitis, trial design

Incl committee @DeMadaria 🇪🇸 gracias Enrique🙌

https://t.co/K2G6XSo7hH

[Flavio G Rocha, MD, FACS, FSSO @FlavioRochaMD]

The evidence would support performing diag
laparoscopy prior to #NAT💊 and surgery✂️

22% detection rate of occult metastases on🥢
in upfront resection pts in modern series with
high quality imaging 🖥️ at experienced center

@PanCAN @SocSurgOnc @IHPBA

https://t.co/2FtHbBcSVz

[Syed A. Ahmad @SyedAAhmad5]

Staging laparoscopy to detect occult metastases in localized pancreatic cancer: global survey among nine international societies https://t.co/gt9Z1ZK1z8

[Thomas Stoop @TFStoop]

@CUSurgOnc @CUpancreas @CUDeptSurg @ObaAtsushi Congratulations Atsushi & @chiaro_del, truly wonderful🥇!!

[CU Surgical Oncology @CUSurgOnc]

The Division of Surgical Oncology is thrilled to welcome Atsushi Oba, MD, PhD as Associate Professor of Surgery at the University of Colorado Anschutz Medical Campus! @CUpancreas @CUDeptSurg @ObaAtsushi #ImproveEveryLife

[Giovanni Marchegiani @Gio_Marchegiani]

Staging laparoscopy 🙈 waste of time or added value!?

🗣️ 617 Surgeons / 76 countries
⏱️ Mostly performed same session laparotomy
🧐 Useful in suspicious radiology / ⬆️ CA 19.9

👉 Does not hurt + increase staging accuracy

https://t.co/nmrLxzgnfk

[Thomas Stoop @TFStoop]

@MarcBesselink @Gio_Marchegiani @BasGrootKoerkam @IHPBA @JSHBPS @chiaro_del @Caspervaneijck @EAHPBA

[Thomas Stoop @TFStoop]

In @hpbjournal, 🌎 survey on use & indications of staging laparoscopy in #PDAC (617 surgeons, 76 countries):
📎82% uses SL
📎geographic variety
📎mainly in only selected patients
📎read more about timing & diagnostic adjuncts 👉 https://t.co/09oq5Lnxqw

📯more evidence⚠️

[Arndt Vogel @ArndtVogel]

Hepatic Arterial Infusion Pump Chemotherapy in Unresectable Intrahepatic Cholangiocarcinoma
🔎PUMP-2 Trial
@JCO_ASCO
https://t.co/EYzS3tF0Zp
👉48 pts HAIP floxuridine + CTx
👉PR: 44%; DCR: 84%
👉1-year OS: 80.0%
🧐strong signal, interesting opportunity for downstaging,
👉looking forward to the next trial

[Ernesto Sparrelid @sparrelid]

As of last Friday, I am a Professor of Surgery @karolinskainst, adjunct to my position as Senior Consultant Surgeon @KarolinskaUnsju. While this is, of course, a personal achievement, it also represents recognition of all members of the @HpbKarolinska

[Marc Besselink @MarcBesselink]

Endoscopic or surgical #gastroenterostomy for palliation malignant gastric outlet obstruction?

🚀Today @LancetGastroHep: #ENDURO randomised multicenter trial @DPCG_official 🇳🇱

Excellent nationwide collaboration #surgery & #gastroenterology 🙌

⏩️ https://t.co/HbwvlCrqgR