Simon eccleshall

[Simon eccleshall @Simoneccles66]

@jonnywatt @evandrofilhobr Ok so you have to trade off a slightly higher 1 year repeat revasc rate for SEB against a slightly higher cardiac death rate in DES

Death is undoubtedly the ultimate endpoint.

A repeat revasc is a choice…

Time to start making choices

[Simon eccleshall @Simoneccles66]

@djc795 @sbrugaletta Mine too. See you in another 4 years!

Or hopefully sooner with a beer!

[Simon eccleshall @Simoneccles66]

@MarqPatton @sbrugaletta That’s not the point. A strategy of DCB first and DES when needed is being tested. The result is 80% fewer patients need a DES and the outcome in non-inferior

Why leave them with a DES if not needed. We all hate ISR and DES-induced ACS - poor PCI outcomes

[Simon eccleshall @Simoneccles66]

@djc795 @sbrugaletta We have published cost effectiveness already showing even with higher price on DCB that overall procedural cost v similar in a UK setting .

And not longer procedural time

and not more contrast

[Simon eccleshall @Simoneccles66]

@djc795 @sbrugaletta How many layers of metal are good? One? Two?? Three???

If you want to avoid ISR and worse (stent thrombosis) then you only need the DES for failed lesion prep. If your concern is restenosis just deliver the drug don’t leave metal behind

[Simon eccleshall @Simoneccles66]

@MarqPatton @sbrugaletta But that means 80% of your cases can leave the lab stent-free and avoid those documented stent attrition rates seen out to at least 10 years. Why wait 10 years - it is safe and non-inferior at one.

GAME CHANGER😎

Mic drop….

[Simon eccleshall @Simoneccles66]

@ihtanboga Obviously! It’s a game changer

[Simon eccleshall @Simoneccles66]

@cordis DEBonly anyone???? 😎

[Shikha Jha M.D.🫀 @Shikha_Cardio]

#LBCT - SELUTION DeNovo Trial 🌟
At 1 year, PCI strategy with SELUTION DEB and provisional DES was non-inferior to the systematic use of DES for primary end point of TVF. #TCT2025 @crfheart @TCTConference @TCTMD 💙🫶

[Simon eccleshall @Simoneccles66]

@DrPascalMeier I will try but don’t use many anyway !😀

Only required for failed lesion prep and a vessel threatening dissection. So good prep and avoiding or modifying those nasty dissections gives you lots of options for a stent free result

[Simon eccleshall @Simoneccles66]

@realarainmd Absolutely. Do your best lesion prep then choose the right destination device. We have the choice of DCB, scaffold or DES

PCI is changing (again)

[Simon eccleshall @Simoneccles66]

@angioplastyorg I have just watched it

WOW WOW WOW

he is (still) so far ahead of the game

Amazing

Thank you

[Simon eccleshall @Simoneccles66]

@angioplastyorg BALLOON SUNDAY - love it!

BALLOON EVERYDAY 🤩

[Stefan Harb @stefan_harb]

SELUTION DENOVO strategy with sirolimus #DCB has met noninferiority margin.
⁦@crfheart⁩ ⁦@TCTConference⁩ #TCT2025

[Mamas A. Mamas @mmamas1973]

My @TCTMD with @Simoneccles66 and christian spaulding around #SelutionDeNovo trial @crfheart @jgranadacrf

[Simon eccleshall @Simoneccles66]

@drrajnatarajan @vass_vassiliou @CorballisTash @justvick Great work Raj! Well done

DCBonly just keeps expanding

[Simon eccleshall @Simoneccles66]

@upulwick @bit @SanjogKalra @aayshacader Awesome job as always Upul!!

[Simon eccleshall @Simoneccles66]

@Atul_SharmaMD @mmamas1973 @vass_vassiliou Best treatment for residual thrombus is good DAPT etc plus TIMI 3 FLOW IMHO

[Simon eccleshall @Simoneccles66]

@Hragy @amrelhadidyy And thanks again for the invitation

[Simon eccleshall @Simoneccles66]

@Hragy @amrelhadidyy Thank you! I hope it was useful educational and entertaining! So much to talk about in DCB land !