Simran Manoj Gupta

Ph.D. Scholar @IISERPune @Hari_Chakrapani Lab l Chemical Biologist l Alumnus of Institue of Science Nagpur

[Simran Manoj Gupta @SimranGupta2312]

Delighted to start 2025 with the publication of my latest first-author paper with @sumanchemX in @angew_chem Extremely grateful for the guidance and support from my mentor @Hari_Chakrapani throughout this journey. Looking forward to the next chapter in my research. @IISERPune

[Harinath Chakrapani @Hari_Chakrapani]

Pleased to share our latest manuscript "Tandem Biocatalysis to Generate Hydrogen Sulfide and Promote Endogenous Antioxidant Response" has been accepted in Angewandte Chemie International Edition https://t.co/6MAdTo61J4. @KamatLab_IISER @ANRFIndia @IISERPune

[Simran Manoj Gupta @SimranGupta2312]

@Mr_ACID_ @ChemicalScience @oovijit7777 @I_m_Nilu @TanwarRiteeka Congratulations to the team 🎉

[Simran Manoj Gupta @SimranGupta2312]

Participated in Redox Week Conference last week in Sendai. I had the privilege of delivering an oral presentation on my PhD research, as well as presenting a poster. Extremely thankful to my PhD supervisor @Hari_Chakrapani for his guidance.
https://t.co/FxlmfZxEoG
@IISERPune

[Simran Manoj Gupta @SimranGupta2312]

Honored to be selected for the Japan Sakura Science Exchange Program, Japan Science and Technology Agency and have started my journey. Many thanks to Prof. Takaaki Akaike @STakaaki26424 and his lab at Tohoku University, Japan for the warm welcome. Looking forward to this journey.

[Angewandte Chemie @angew_chem]

Tandem Biocatalysis to Generate Hydrogen Sulfide and Promote Endogenous Antioxidant Response (Harinath Chakrapani and co-workers) @hari_chakrapani @iiserpune • https://t.co/mw4gYx0Vlx

[Simran Manoj Gupta @SimranGupta2312]

Beyond excited to announce my first-ever first-author paper published in Chemical Science! Deeply grateful to my supervisor, @Hari_Chakrapani , for his invaluable guidance, and to my wonderful labmates. Here’s to new beginnings! @IISERPune @ChemicalScience
#MyFirstChemSci

[Harinath Chakrapani @Hari_Chakrapani]

Pleased to share our first manuscript in 2025 published in @ChemicalScience https://t.co/9hD9pcsCoS. Congratulations @SimranGupta2312 and Pratiksha! @IISERPune @IndiaDST @ANRFIndia for funding.

[Simran Manoj Gupta @SimranGupta2312]

Heartiest Congratulations to Prof. Siddhesh Kamat @KamatLab_IISER @IISERPune

[Infosys Prize @InfosysPrize]

#InfosysPrize2024 in Life Sciences is awarded to Prof. Siddhesh Kamat, @KamatLab_IISER, of @IISERPune for his discoveries concerning bioactive lipids and their receptors, and their metabolic and signaling pathways. His research using advanced methods to understand the function of lipids, a key component of cells, has important implications for understanding the role of these molecules in a range of cellular functions and human diseases.

[Simran Manoj Gupta @SimranGupta2312]

Participants of the Indo-German Meeting #ECBS-2024 at Le Meridien Amritsar, coinciding with 50 years India and Germany S&T cooperation.@INDOGSTC @GermanyinIndia Excited to share that I’m participating this year! Looking forward to connecting with experts, learning new ideas.

[Sandeep Verma (स्वर) @Sandeep_1966]

A backdrop like no other for the conference group photograph! Special place and special occasion, with special friends. Splendid time!
India 🇮🇳 🇮🇳

[Sandeep Verma (स्वर) @Sandeep_1966]

Participants of the Indo-German Meeting #ECBS-2024 at Le Meridien Amritsar, coinciding with 50 years India and Germany S&T cooperation. Anticipating complex multidisciplinary science, involved interactions and useful collaborations. @INDOGSTC @GermanyinIndia

[Harinath Chakrapani @Hari_Chakrapani]

Delighted to share our foray into selenium chemistry - now published in @ChemicalScience https://t.co/Zh0LQtPDHF Congratulations @DeySarkar2 and Mahima! Thanks @IISERPune @ChemistryIISERP @serbonline for funding. @RoySocChem

[Harinath Chakrapani @Hari_Chakrapani]

We're looking for a highly motivated and enthusiastic Research Associate with expertise in organic synthesis and mechanisms, and a demonstrated research track record. Those interested may please check the link: https://t.co/qjwCuZ5B1a

[Siddhesh Kamat @KamatLab_IISER]

Happy to share a new paper (@BiochemistryACS) from the lab @IISERPune assigning PLC-type activity with specificity towards phosphatidylinositol lipids to an uncharacterised lipase CG17192 in flies during infection. Wonderful work led by @Kundan703. https://t.co/aO8cnbTr9E

[Suman Manna, PhD @sumanchemX]

As killing latent HIV-1 is almost impossible hence our strategy may enable us to kill and clear HIV-1 viruses (known as the Shock and Kill strategy). Many thanks to my PhD supervisor @Hari_Chakrapani, and collaborators (Amit Singh lab & @AdhesionLab ). https://t.co/r4bX5o8ZpG

[Suman Manna, PhD @sumanchemX]

Extremely pleased to share my publication in Angewandte Chemie.
Started this project just before the COVID-19 viral pandemic. Only had NMR and some preliminary data. Never thought that this could lead to interrogation of HIV-1, another deadly virus.

[Harinath Chakrapani @Hari_Chakrapani]

@AdhesionLab @suman_chembio @angew_chem @IISERPune @ChemistryIISERP Using this tool, we studied the effect of mitochondrial H2S on human immunodeficiency virus (HIV-1) and mitochondrial H2S and persulfide profoundly affected the HIV-1 life cycle and may provide clues such to new drug design @Mito_News

[Harinath Chakrapani @Hari_Chakrapani]

Check out the latest probe from our lab: the cell’s biosynthetic machinery and localization is used to selectively generate H2S within mitochondria. Collaboration with Amit Singh and @AdhesionLab @suman_chembio @angew_chem
https://t.co/3jbK4EK9MF @IISERPune @ChemistryIISERP

[Harinath Chakrapani @Hari_Chakrapani]

Delighted to share this paper in Redox Biology from Amit Singh Lab and our lab. How Mycobacterium tuberculosis (causative agent of TB) deals with the endogenous redox species peroxynitrite is studied. https://t.co/0UOiOoZNxw @iiscbangalore @IISERPune @DBTIndia @ChemistryIISERP

[Simran Manoj Gupta @SimranGupta2312]

Had an incredible week at the GRC in Barcelona, Spain!It was such a privilege to present poster preview talk and engage with fellow researchers in my field. Sharing my research and exchanging ideas was a valuable experience. Thiol-Based Redox Regulation and Signaling @GordonConf

[Vladi, Uladzimir Barayeu @Sulfur_Vladi]

Thanks to all the participants of the Thiol GRS, that slowly turns to the persulfide GRS-SH.
Congratulations to the winners of the talk: @juliamalopueyo, poster: @ClaudiaLennicke, @TaylorCovingt10, Thomas Foy; and question prizes @tzu_keng.