Sivaraman Padavattan

Additional Professor, Department of Biophysics @NIMHANS_BLR | Research interest: Alzheimer's disease, Parkinson's disease, Chromatin, Structural Biology

[Sivaraman Padavattan @SivaramanLab]

@Jain_Lab @bgurnani05 @Chapman_Lab @mattchapman22 Congratulations Neha and team.

[Sneha @Jos_sneha]

Our work proposing an early-stage model that challenges the traditional aggregation-centric views for protein deposit (Lewy body) formation in Parkinson's Disease was featured in The Hindu today !

Link: https://t.co/GqfGM7vl3B

[Sivaraman Padavattan @SivaramanLab]

I am thankful to my team, @Jos_Sneha and Niharika Shivanandaswamy, and to our collaborators, @NathSangeeta, Neelakandan’s team at @DBT_inStem, and Deepak Sharma at @CSIR_IMTECH.
We are grateful to @ANRFIndia and @NIMHANS_BLR for the support that made this work possible.

[Sivaraman Padavattan @SivaramanLab]

Our latest study in @CommsBio revisits how α-synuclein drives Lewy bodies formation. We propose a new concept:
👉 Multifactorial Random Disorder Model
to explain how diverse biomolecules are sequestered during LB formation.
https://t.co/SAEMbg5r1n
#ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration #Biomarkers #DrugDiscovery

[Sivaraman Padavattan @SivaramanLab]

My student, @Jos_sneha, is capturing a beautiful illustration of how α-synuclein drives Lewy body formation.
Science meets art—perfectly!
#ParkinsonsDisease #LewyBodies #AlphaSynuclein #Neurodegeneration

[Sivaraman Padavattan @SivaramanLab]

@Chauhanlab_ILS @DeepakNModi @ICMRDELHI @ANRFIndia @DBTIndia Very true.

[Sivaraman Padavattan @SivaramanLab]

@Jain_Lab @khushboo251995 @bsbe_iitj @iitjodhpur Congratulations.

[Sivaraman Padavattan @SivaramanLab]

@ruchianand1975 @SombuddhaS @raj_at_iitb @ANRFIndia @iitbombay @India_Alliance @SMSDLab_IITB @BattyBoffin @prem_s_kaushal @lab_engel @NACB_IITB Congratulations Ruchi and team.

[Sivaraman Padavattan @SivaramanLab]

@kmoharir @Jos_sneha Thank you

[Sivaraman Padavattan @SivaramanLab]

A proud moment today—my first PhD student, Ms. @Jos_sneha, submitted her thesis. She completed her PhD with 9 publications, including 2 papers in Communications Biology (Nature Portfolio), J Mol Biol, and Protein Science.
Congratulations, Sneha! 🎓👏
#PhD #Mentorship #StructuralBiology #Neuroscience #NIMHANS

[Sivaraman Padavattan @SivaramanLab]

🧠 Lewy bodies—the pathological hallmark of #Synucleinopathies
How does α-synuclein sequester diverse biomolecules within the crowded cellular environment to drive Lewy body formation?
#AlphaSynuclein #LewyBodies #ParkinsonsDisease #Neurodegeneration #NIMHANS

[Sivaraman Padavattan @SivaramanLab]

@Jain_Lab @Jos_sneha Thank you Neha. Indeed.....Yes.

[Sivaraman Padavattan @SivaramanLab]

@NathSangeeta @Jos_sneha Thank you Sangeeta.

[Sivaraman Padavattan @SivaramanLab]

#alphaSynuclein #LewyBody #ParkinsonsResearch #Neuroscience #NIMHANS

[Sivaraman Padavattan @SivaramanLab]

NIMHANS PhD applications are now open!
Our Chromatin Structural Biology Lab at NIMHANS is looking for highly motivated candidates with CSIR/UGC/ICMR/DBT fellowships (or equivalent) for a PhD position to work on key proteins associated with Alzheimer’s and Parkinson’s disease.
Interested candidates may reach out or apply through the NIMHANS PhD portal. Please share with potential applicants. @NIMHANS_BLR

[Sivaraman Padavattan @SivaramanLab]

Proud moment for @SivaramanLab!. My student @Jos_sneha won the Best Paper Award at the Indian Academy of Neuroscience 2025 meeting at @RGCB_Trivandrum for our recent paper on the nuclear role of alpha-synuclein associated with Parkinson's disease https://t.co/0O1fcN5cug. Thanks to @ANRFIndia and @NIMHANS_BLR

[Sivaraman Padavattan @SivaramanLab]

I am pleased to share that I have been promoted to Additional Professor in the Department of Biophysics at #NIMHANS.
I am grateful to my mentors, students, colleagues & family for their constant support.