Snitkin Lab

We apply genomics to understand the epidemiology and evolution of resistant pathogens.

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

Strain Variation in Clostridioides difficile Cytotoxicity https://t.co/mpx9hGnaor @SnitkinLabWGS Hanna/Snitkin Identified genomic variants most correlated w/changes in phenotypes & disease severity. Overlapping loci may be important for bacterial function & human clinical disease

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

Ferric Citrate https://t.co/xpa6cyIXj2 @harry_mobley @SnitkinLabWGS Snitkin-Mobley: Ferric citrate uptake has not previously been associated w/UPEC isolates, underlining the importance of the continued study of these strains to fully understand their mechanisms of pathogenesis.

[Snitkin Lab @SnitkinLabWGS]

We are excited to publish our framework for studying regional transmission using whole-genome sequencing data.

Check out our corresponding open-source R package, regentrans 👇

https://t.co/uDUEXclZKp

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

regentrans https://t.co/QrIB9jOHSY @SnitkinLabWGS Snitkin Lab presents framework for studying regional pathogen transmission using whole-genome sequencing data, & corresponding open-source R package, regentrans,

[Snitkin Lab @SnitkinLabWGS]

Congrats to @GenevieveChiara, @SnitkinLabWGS member & @umichsph MPH in Hospital & Molecular Epidemiology candidate, for her successful MPH capstone presentation:

"Validation of strain profiling tool strainEST using Clostridium difficile population sequencing."

Great work! 🥳🎉

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

Phenotypic & https://t.co/Sg6Bq6AcCn @SnitkinLabWGS @ericmartens1 Snitkin/Martens results provide paths to expand phenotypic surveys of more diverse gut bacteria to understand their functions & also to leverage dietary fibers to alter the physiology of the gut microbial community

[Snitkin Lab @SnitkinLabWGS]

Congrats to Dr. Stephanie Thiede! 🧫🦠

@stephstaph8 successfully defended her excellent dissertation, "Genomic Epidemiological Insights Into MRSA Transmission and Adaptation in an Urban Jail and the Surrounding Community" today. Congrats!🎉

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

First post COVID PhD defense with at least some in person. Congrats soon to be Dr Stephanie Thiede and her mentor Evan Snitkin!

[Dept of Microbiology & Immunology @ the Univ of MI @UMMicroImmuno]

From the Snitkin Lab - work highlighting the prevalence of multiallelic sites and SNPs in overlapping genes within diverse bacterial genomes and the impact of reference allele choice on gene-based analyses.
https://t.co/eSzPCBX9my

[Snitkin Lab @SnitkinLabWGS]

Our latest preprint by @5hawnsolo with @mhayde2's group is out!

[Shawn Hawken @DrShawnSolo]

So excited our newest preprint from @SnitkinLabWGS & @mhayde2 is up! We used a SNV threshold free method to integrate #WGS and #Epi data to identify routes of #CRE transmission in an LTACH. #epitwitter #Genomics
https://t.co/NJieYnmn7j

[Snitkin Lab @SnitkinLabWGS]

Excellent work by @saund_katie on the implementation of new bacterial #GWAS methods!!

[Katie Saund @saund_katie]

My third thesis paper with the @SnitkinLabWGS is out today! We originally began this project so that we could implement @MahaFarhat & @bjesseshapiro's phyC algorithm in R for one of our Cdif genomics projects. 1/4

[Snitkin Lab @SnitkinLabWGS]

Are patients or hospitals a more important predictor for #antibioticresistance dissemination? Our latest work in @IDSAInfo teases them apart! Special thanks to @CDCgov for funding this research. #GoBlue #Genomics #epidemiology
https://t.co/BgsGR7t0Ik

[Snitkin Lab @SnitkinLabWGS]

Congratulations @5hawnsolo! We have been so fortunate to be part of your amazing journey. Best of luck in all your future endeavours!! #GoBlue @UNC_Clin_Micro

[Scott Hawken @ScottHawken]

Congratulations Dr S Hawken PhD!!! ⁦@5hawnsolo⁩ ⁦@SnitkinLabWGS⁩

[Snitkin Lab @SnitkinLabWGS]

It's happening! First graduate trainee @5hawnsolo from the Snitkin lab is defending her PhD work today at 2 PM (EDT)! All are welcome to see her hard work on combating infectious diseases in long-term care via https://t.co/IxUJuTEjVv
@UMMicroImmuno (photo credit: @stephstaph8 )

[Snitkin Lab @SnitkinLabWGS]

🎶🎅🎄❄️☃️It's beginning to look a lot like...sickness here in the Snitkin lab for the annual Bioinformatics Door Dec Contest. Elf on the shelf should have gotten his DTaP vaccine before he sat on that rusty nail...... @UMMicroImmuno #IDtwitter #SantaIsComingDownWithSomething

[Snitkin Lab @SnitkinLabWGS]

Thanks to invitation by @UMichEEB, Evan takes us through cool work by @5hawnsolo, Zena Lapp, @alipirani88, and many amazing collaborators in understanding CRKP transmission! #AntibioticResistance #GenomicEpi

[Snitkin Lab @SnitkinLabWGS]

Snitkin lab is participating in the holiday-themed door decoration contest hosted by the Bioinformatics department! Thanks to @stephstaph8 @5hawnsolo @saund_katie @RDCrawford26 @alipirani88 @bubblepig914 and @Sintsovka for #mandatoryfun!

[Snitkin Lab @SnitkinLabWGS]

Watch it here!! https://t.co/eqPmicNnDK

[Snitkin Lab @SnitkinLabWGS]

Faculty corner: Chalk talks! @umichmedicine @umichgradschool

[Katie Saund @saund_katie]

Fascinating paper by @anishpandey89 on #BacterialEvolution in upper respiratory tract. I made a #VisualAbstract as I was reading to keep the two studies straight.

Paper: https://t.co/oT6BBhApiu

RT: https://t.co/KSNZxuRzEN

[Snitkin Lab @SnitkinLabWGS]

@umpda

[Snitkin Lab @SnitkinLabWGS]

Goodbye lunch for Hannah - awarded a CDC/CSTE Applied Epidemiology Fellowship, and @genevievechiara - thank you for all your hard work this summer! Best of luck to you both and hope to see you soon! @CSTEnews