Posting our lab life studying the neuronal cytoskeleton and chromatin with cool microscopes🔬Proud #GenX, #firstgen college, #intj @RITscience @stonybrooku Alum
Thrilled we finished this 8 yr study w/@NeuroCellPress Wonder what oxygen, blood vessels, Hif1 has to do with cell polarity & neuron migration? Genetics, gaussian & lattice light-sheet crack the case! Cerebellar blood vessels in cyan #cellfie#Science
url:https://t.co/PJ9lltGztm
Out now in Science! Our new study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵
https://t.co/w5mYmh4I1G
Still one of the purest dopamine hits in science:
Thank you for your submission.
For one brief, beautiful moment… the paper is someone else’s problem.
Reviewer 2 can cook me later. 🔥
Still one of the purest dopamine hits in science:
Thank you for your submission.
For one brief, beautiful moment… the paper is someone else’s problem.
Reviewer 2 can cook me later. 🔥
Post-graduation jaunt through Santa Fe country. Beautiful enough to make you forget the altitude for a minute. Rattler skin reminder of who really runs the joint 😳
Post-graduation jaunt through Santa Fe country. Beautiful enough to make you forget the altitude for a minute. Rattler skin reminder of who really runs the joint 😳
💥 🚀 New preprint! 🎉🥳
How do hundreds of organelles organize themselves into near-perfect patterns inside a cell, without a blueprint? We dive deep into how basal bodies (BBs) self-organize in MCCs - and how actin actively tunes their dynamics into order 🍪
🧵👇 (1/17)
Mind-blowing cell action alert!
Watching vesicle cargo lanes light up like a
@FedEx highway in real-time under the #microscope.
Who knew that home-brewed phosphatidic acid live cell imaging probe would look so stunning in human fibroblasts?
Which organelle do you think its labeling? Drop your guess below!
Too late for #FluorescenceFriday but just in time for #MicroscopyMonday #scicomm #sciart #Science
Mind-blowing cell action alert!
Watching vesicle cargo lanes light up like a
@FedEx highway in real-time under the #microscope.
Who knew that home-brewed phosphatidic acid live cell imaging probe would look so stunning in human fibroblasts?
Which organelle do you think its labeling? Drop your guess below!
Too late for #FluorescenceFriday but just in time for #MicroscopyMonday #scicomm #sciart #Science
Turns out some virus's get stuck in late endosomes under high membrane tension! Making them unable to infect cells!
Congrats to the Tklab Virus Team for our paper @PNASNews. Live 3D LLSM imaging + single cell infection assay! @harvardmed@BostonChildrens
https://t.co/2kMVT8rU1V
We have developed a cysteine-free, highly thermostable tagging system, UTag, that enables single-mRNA translation tracking in live cells. You may wonder how different tagging systems affect translation kinetics—we addressed this by performing a systematic comparison.
📣 Preprint!! Hugely excited for this new direction, an ongoing collaboration with the talented labs of Zoe McElligott and Gina Leinninger. From the McElligott lab - Biased NTSR1 signaling regulates the extended amygdala and suppresses motivated feeding. 🐭 🍩
Check it out 👇