Glendon Pflugrath

Clinical Microbiologist;
Backpacker, Gardener;
Cybernetic Beliefs.

«Greetings, bot! Take me to your leader.»

[Glendon Pflugrath @Squelchy_]

Polly Matzinger, PhD
The NIH Videocast Lectures

🧵#1: "Class Control: The Other Side of Tolerance" 10 Sep 2008
🧵#2-9: Graduate Seminar, "Danger-Based Immunology Course"

(Recommend you take an undergraduate Immunology course before the seminar series.)

https://t.co/7GYW6xGVuc

[Glendon Pflugrath @Squelchy_]

@AGHuff @grok Would be reasonable to say that this sets our Bayesian priors in support of a resistant stain emerging from this scenario as weakening the case for natural exposure, while not eliminating the possibility.

[Glendon Pflugrath @Squelchy_]

@AGHuff @grok Установлено, что для всех исследованных штаммов МПК выбранных АБП [антибактериальным препаратам], определённые методом серийных разведений в агаре [метод золотого стандарта], соответствовали значениям для чувствительных штаммов возбудителя чумы, представленным в [стандартах].

[Glendon Pflugrath @Squelchy_]

@grok @AGHuff Thanks for the assist, grok.

[Glendon Pflugrath @Squelchy_]

@AGHuff Does that region have unusual acquired resistance patterns?

The uninitiated aren't going to typically recognize intrinsic resistance as resistance.

When I hear this from laymen, I interpret as resistance to empiric therapy. First line drugs, or possibly into the alternatives.

[Glendon Pflugrath @Squelchy_]

@yoshkapundrick @hemultiplyus @angie_rasmussen Trust the model, bro.

[Glendon Pflugrath @Squelchy_]

@thedarkhorsepod If predictive power is the "coin of the realm", the diary had more real-time value than the public utterances.

[Glendon Pflugrath @Squelchy_]

@thereal_truther @DrJ_surgeon @weldeiry Tell me you don't understand epistemology without telling me you don't understand epistemology.

Clinical experience doesn't fit so neatly into your inherited dogma, treating guidelines as if law. Case reports, broadly, may have lower value while, specifically, be the key insight

[Glendon Pflugrath @Squelchy_]

@scotthortonshow @zei_squirrel She bought them a few years there, as her parents remember on DemocracyNow.

https://t.co/oXqIxDpFkf

[Scott Horton @scotthortonshow]

@zei_squirrel He father told me in an interview years ago that there was a family in the house she was protecting. She saved their lives.

[Glendon Pflugrath @Squelchy_]

@DrJoelGator Used to be that we wanted to retain our means of TB screening using PPD, and vaccination causes that screen to be falsely positive.

Now that we screen with IGRA methods, perhaps we need to reevaluate whether a low efficacy vaccine is worthwhile for selected populations?

[Glendon Pflugrath @Squelchy_]

@grok @AmyMorg56188253 @rustyrockets @RealCandaceO Grok, would you please revisit this response? Provide quotes.

[Glendon Pflugrath @Squelchy_]

@michaelmalice Looks like your teenth time...

[Glendon Pflugrath @Squelchy_]

@in_my_red_era @angie_rasmussen Relates to the Spanish Flu pandemic, with aspirin still a new product. Proposes that deaths could be attributable to aspirin overdosing, explaining the paradoxical over representation of young&previously healthy dying in their own fluids. Pharmacology still primitive at the time.

[Glendon Pflugrath @Squelchy_]

@RefineRenew @IanCopeland5 @BretWeinstein Ian has, specifically and in detail, himself been implicated within Covid conspiracy. Highly aggressive bad faith argumentation protecting the cover stories, patrolling this platform with a cadre to attack anyone who threatens the narrative with logic, reason, and basic humanity.

[Glendon Pflugrath @Squelchy_]

@spilkommen @BretWeinstein @TherionWare Okay, I'll bite. What's the logical fallacy here?

Conspiracies are common, conspirators hide under cover stories. Are you suggesting that the available evidence will necessarily provide a simpler explanation than the cover story?

With insufficient evidence, the truth is lost.

[Glendon Pflugrath @Squelchy_]

@Rainmaker1973 So, would be safer if we... shut down parts of the immune system?! What could go wrong?

[Glendon Pflugrath @Squelchy_]

@BretWeinstein @RWMaloneMD Confirmatory testing is warranted, because that high cycle threshold setup is what's used for screening tests.

Perhaps if positive results had reflexed confirmation using an antigen test and/or an assay for IgM antibody we'd have more accurately picked out the true positives.

[Glendon Pflugrath @Squelchy_]

@BretWeinstein @RWMaloneMD Would expect the Covid PCR to be highly sensitive when set to a 45 cycle threshold and thus provide strong negative predictive value (NPV), but that compromises specificity and risks poor positive predictive value (PPV): few false negatives in exchange for more false positives.

[Glendon Pflugrath @Squelchy_]

@Rainmaker1973 An apology to everyone afflicted by her software would be a good use of that fortune. For those of us that spend chunks of our day enslaved to fixing problems caused by inane software development.