Sri Pusala

I like health and tech

[jo johnson @josbjohnson]

be aggressively delusional about your future until it’s simply your present. the vision is yours and it’s supposed to look insane from the outside. stay so committed to it that reality has no choice but to adjust. believe so hard in what you’re building that the present starts bending toward it. and one day you’ll wake up and the thing everyone called impossible will just be your life. and they’ll ask how you did it. and you’ll tell them: you never stopped believing. you just started working like it was inevitable.

[UroToday.com @urotoday]

#MoonRISe1 trial: Evaluating TAR-210 for FGFR-altered intermediate-risk #NMIBC. @UrogerliMD @MoffittNews joins @zklaassen_md @GACancerCenter to discuss how this technology could significantly reduce the burden of repeated procedures and treatments.
#WatchNow > https://t.co/CMfz9X7cCk

[Sri Pusala @SricharanPusala]

Thinking Drug repurposing, target discovery, predictive biomarkers, & model training…@Regeneron now owns the full stack.

Need 500 FGFR3-mutant BCG unresponsive NMIBC pts? You’ll have it.

Hypothesis validation is going to speed up drugs are going to be built smarter & faster.

[Sri Pusala @SricharanPusala]

$256M for a dataset of 15M genetic profiles and longitudinal health tracking infra is wild.

This is a platform play: real-world evidence + genomic insights = The future of decentralized, continuous clinical trials. Forget one-off moonshot drugs. This is a pipeline accelerator.

[Crémieux @cremieuxrecueil]

23andMe failed because of management problems, not because there wasn't anything there.

And their research team knew it.

They published a report last year that noted they had found over 2,000 solid drug targets, but the work just wasn't being done.

[Sri Pusala @SricharanPusala]

Welcoming foreign trained doctors with the right safeguards is people-first progress. Curious to see how global talent can help close the gaps to patient access. But we can’t stop here, targeted incentives or service obligations to resource intensive areas will be the key.

[Malke Asaad @malkeasaad]

➡️ Florida has started accepting applicants for the new route to practicing in the 🇺🇸 United States without residency!

📖 Read more here: https://t.co/r7hCKTGZYi

📝 You can apply here: https://t.co/56rJAEcw7F

🤙 Schedule a Free Strategy Call with our customer support team to answer any questions you have about The Match Guy services: https://t.co/vqhTKSDAvI
.
.
.
#IMGs #MedicalLicense #FloridaDoctors #USMLE #InternationalDoctors #PracticeWithoutResidency #FLMedicalBoard #HealthcareNews #DoctorLife #MedTwitter #MedSchoolJourney 🩺

[Sri Pusala @SricharanPusala]

If Brellium succeeds, it won’t just help healthcare organizations pass audits.

It may reshape how compliance is built into the EMR, one visit at a time. It may opne up dialouge around the restructuring of legacy protocl sluggish institutions have in place.

First time taking a stab at X to build out my Yacth, as the @TheRealEstateG6 taught me. Follow for more healthtech and clinical trial insights.
DMs open.

#AI #DigitalHealth #Oncology #ClinicalTrials #HealthTech

[Sri Pusala @SricharanPusala]

Big news in #HealthTech I've been looking into this weekend:
@BrelliumHealth just raised $16.7M, Series A, running towards AI-powered compliance automation to healthcare. But this isn’t just another SaaS startup.
Brellium has real implications for oncology, clinical trials, and revenue cycle integrity.
Here’s what it means:
[THREAD]

[Sri Pusala @SricharanPusala]

Working closely in clinical trials, payor workflows, and financial reconciliation, I’m watching Brellium closely.

It’s one of the platforms I strongly beleive could scale financially and operationally in a space where most legacy tools stall at integration.

[The Real Estate God @TheRealEstateG6]

https://t.co/ZzElO1BblU

[signüll @signulll]

it feels like instead of us all stepping into the future together, a few of us are watching our world change on a daily basis, while the remaining masses will one day have a startling realization that the world is radically different.

[ELON CLIPS @ElonClipsX]

Marc Andreessen: Elon inspires incredible loyalty from his employees because they know he'll sit all night with them to solve a problem.

“Elon actually delegates almost everything. He's not involved in most of the things that his companies are doing. 

He's involved in the thing that is the biggest problem right now until that thing is fixed.

And then, he doesn't have to be involved in it anymore, he can go focus on the next thing that's the biggest problem for that company right now. 

In manufacturing, there's this concept of the bottleneck. In any manufacturing chain, there's always some bottleneck, something that is keeping the manufacturing line from running the way that it's supposed to. Whatever the bottleneck, it's holding everything up. 

The job number one is to remove that bottleneck and get everything flowing again. I think Elon basically has universalized that concept and he basically looks at every company like it's some sort of conceptual assembly line. 

I don't need to manage everything else because everything else, by definition, is running better than that. I can go focus on that. 

A lot of CEOs, especially non-technical CEOs, would really struggle to implement his method. When he identifies the bottleneck, he goes and he talks to the line engineers who understand the technical nature of the bottleneck. 

If it's people on a manufacturing line, he's talking to people directly on the line. Or if that's people in a software development group, he's talking to the people actually writing the code. 

He's not asking the VP of Engineering to ask the Director of Engineering to ask the manager to ask the individual contributor to write a report that's to be reviewed in three weeks. He doesn't do that. He would throw them all out of the window. There's just no way he would do that. 

He goes and personally finds the engineer who actually has the knowledge about the thing, and then he sits in the room with that engineer and fixes the problem with them. 

This is why he inspires such incredible loyalty, especially from the technical people who he works with. They're like, wow, if I'm up against a problem I don't know how to solve, freaking Elon Musk is going to show up in his Gulfstream jet, and he's going to sit with me overnight in front of the keyboard or in front of the manufacturing line, and he's going to help me figure this out.”

Interview of @pmarca by @ChrisWillx on Youtube, December 14, 2024

[Jonathan Swanson @swaaanson]

Elon runs six multi billion-dollar companies simultaneously (SpaceX, Tesla, X, xAI, Neuralink, and Boring Company)

Most founders can’t run one.

Walter Isaacson (who spent a year shadowing Elon and wrote his biography) explains ‘How Elon does it’ on a podcast

Thread 🧵

[Eric Ball @DrEricBall]

I am seeing a child today with the most terrifying chief complaint in pediatrics: "Mother thinks something is wrong with her child."

Mothers are usually correct. I will be ordering tests.