StainsFile

Let’s talk about visualizing cells! 👩🏽‍🔬🔬
We’re an online resource for open-access protocols, reagents, theory, and more.
Brought to you by @STEMCELLTech.

[StainsFile @StainsFile]

Welcome to StainsFile by @STEMCELLTech! Here, you can enjoy easy and open access to all the protocols and supporting resources you need to help you fix, prepare, and stain specimens: https://t.co/v0ZcjTldGM 👩🏽‍🔬💻🧫🔬

#cellstaining #histology #microscopy #microscopymonday

[The Journal of Histochemistry and Cytochemistry @JHCnews]

New this month in JHC: "Two-step Gelatin Embedding Preserves Fibrocartilage Morphology, Enthesis, and Cartilage Stain of Bone Joints."

Click to read: https://t.co/lvKCzqLg1R

#cartilage #histology #immunostaining

[Hao Yin @HaoYin20]

A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution

@michalj @ScienceMagazine 2024
https://t.co/Basp8kqGgF

H01 - 3D serial section scanning electron microscope data (4 nm resolution) of 1.05 mm3 human brain (left anterior middle temporal gyrus, epileptic)

https://t.co/lzQnKgh2Jm

[StainsFile @StainsFile]

CryoPRISM is a new tool from researchers at @MIT for observing cellular machinery in a natural environment.

Dr. Joseph Davis, the study's lead, says that cryoPRISM is the sweet spot between preserving native structures and high resolution: https://t.co/1K3KnchnLA

#Microscopy

[Modern Pathology @ModernPathology]

Bread and butter post: Inflammatory cloacogenic polyp is a mucosal prolapse polyp at the junction of rectal glandular mucosa and anal squamous mucosa. Note that the the lamina propria is filled with smooth muscle rather than the usual complement of inflammatory cells.

[StainsFile @StainsFile]

Before tissues can be stained and studied, they need to be preserved and that’s where fixatives come in.

Selecting the appropriate fixative is an essential step in the staining process to ensure the foundation of your microscopy session is solid. Check out this database of fixatives to make sure you always choose right: https://t.co/RGzOH2QiG7

#HistologyResource

[Nikon Small World @NikonSmallWorld]

Take a look at these fluorescent egg chambers from the ovary of a fruit fly. Isn't the geometric nature of biology incredible?! #FluorescenceFriday

https://t.co/JHbCOLLHE9

Credit: Dr. Yujun Chen

[StainsFile @StainsFile]

MRI quality is often hampered by noise.

Researchers from @Tsinghua_Uni have proposed a new iterative residual learning strategy entitled “Noise2Average” for denoising #MRI data with multiple repetitions.

Read the abstract: https://t.co/YYOf38xeSd

[Sainsbury Laboratory Cambridge University (SLCU) @slcuplants]

Mechanical forces & cell shape guide how plant stomata form🥬👄
@RobinsonSci's team including @LeoSerra13 & Euan Smithers uncover how the interplay between cell shape & mechanical stress influences the orientation of stomata

https://t.co/erpdwyXW9J

https://t.co/h4yfo3Yl1Y

[StainsFile @StainsFile]

A new X-ray imaging technique could transform how hospitals analyse tissue samples, potentially speeding up diagnoses and improving outcomes for patients.

The study was led by researchers at @ucl: https://t.co/3NVMkWWJzm

[The Journal of Histochemistry and Cytochemistry @JHCnews]

New article in JHC: "Transforming Growth Factor-β Drives Epithelial Mesenchymal Transition and Reduces Synthesis of Unelaborated O-GalNAc Glycans in Breast Cancer Cells."

Click to read for FREE: https://t.co/kS4I1deM2f

#breastcancer #EMT #microscopy

[The Joint Pathology Center (JPC) @TheJPCNCR]

High Grade Squamous Intraepithelial Lesion (HSIL) #TheJPCNCR #PathTwitter

[StainsFile @StainsFile]

#Fixation sets the stage for everything that follows. 🔬

From preserving tissue structure to influencing staining outcomes, the choice of fixative matters more than you think.

Brush up on the fundamentals and make more informed decisions at the bench: https://t.co/quoS2VJ8CQ

[StainsFile @StainsFile]

Researchers at @embl have tracked in real time nascent RNA structure formation, functionally characterizing up to 8 different types of RNA molecules.

Learn how they accomplished this with multicolor single-molecule #FluorescenceMicroscopy experiments: https://t.co/qr6EYK4ON6

[allen institute @AllenInstitute]

What is a brain cell but not a neuron? It sounds like a riddle, but our brains are full of lesser-known cells besides the more well known neurons.

In this microscopy image, we see one such cell known as an astrocyte, named for their star-like shape. #SciShots

[STEMCELL Technologies @STEMCELLTech]

Should scientists connect more directly with policymakers? 🏛️

The latest Lab Coats & Life™ Podcast explores how researchers can engage in policy, communicate clearly, and bring a human perspective to real-world decisions.

🎧 Listen wherever you get your podcasts.

[Human Pathology @Human_Pathology]

New in #HumPathol: Thermal resection-margin artifact mimicking goblet cell adenocarcinoma in appendectomy specimens: clinicopathologic correlation with appendiceal stump technique. https://t.co/whNN8r3mOf #pathology #PathTwitter #PathX #GIpath

[StainsFile @StainsFile]

What makes a great #histotechnologist?

It’s more than technical skill. It's a blend of precision, curiosity, creativity, organization, and a commitment to patient care behind the scenes.

Learn how these core traits can make all the difference: https://t.co/8tEpvvX2Zn

[The Histochemical Society @histochemnews]

🎉 Congratulations to the 2026 HCS Capstone Awardees!

Learn more about our Capstone Program here: https://t.co/LZj6hHEU3q

[StainsFile @StainsFile]

Tired of trial-and-error with your antibodies? Finding the right conditions shouldn’t slow you down.

🧫 Get tailored dilutions for your targets in seconds with our Antibody Dilution Finder: https://t.co/F5TGRSr7at

[StainsFile @StainsFile]

Introducing FidlTrack from @Cambridge_Uni!

This new methodology benchmarks and improves Single Particle Tracking fidelity, making understanding dynamic behaviors of macromolecules within live cells even more accessible.

Abstract: https://t.co/OaaLW0zYId