Stanley E. Strawbridge

Group Leader and Fellow in the Physics of Life & Quantitative Biology @sheffielduni. #StemCells #Development #Mathematics #MachineLearning . 🇺🇸🇬🇧

[Stanley E. Strawbridge @StanStrawbridge]

🚨 New Preprint
"Quantification and statistical comparison of cell-state transition kinetics using a parametric failure-based model"
https://t.co/2clWnZZYRH

Cells do not usually change state at a single fixed time.
How can we compare these distributions across conditions?

🧵1/3

[David Turner @da40cambs]

We're accepting self-funded PhD students to work on Wnt and Notch signalling using Gastruloids! Spread the word! https://t.co/CXL6TLc5wC

[Stanley E. Strawbridge @StanStrawbridge]

Thank you to:
Co-author, @AlexGFletcher ;
Host, @sheffielduni;
Funder, @wellcometrust.

[Stanley E. Strawbridge @StanStrawbridge]

🚨 New Preprint
"Quantification and statistical comparison of cell-state transition kinetics using a parametric failure-based model"
https://t.co/2clWnZZYRH

Cells do not usually change state at a single fixed time.
How can we compare these distributions across conditions?

🧵1/3

[Stanley E. Strawbridge @StanStrawbridge]

We view cell-state transition as analogous to system failure & argue that kinetics are a phenotype.

The model separates four features: onset delay, timescale, shape, and competent fraction.

We apply it to pluripotency exit, directed differentiation, and reprogramming.

🧵2/3

[Stanley E. Strawbridge @StanStrawbridge]

⏰ Deadline Approaching! ⏰
📅 15 January 2026

Under two weeks to apply for our fully funded PhD project “Engineering an in vitro human embryo implantation platform to study pathologies arising in early pregnancy” at @sheffielduni. #development #endometrium #materialsscience

[Stanley E. Strawbridge @StanStrawbridge]

I strongly encourage ECRs to apply for opportunities like the Travelling Fellowships from the ever supportive @Co_Biologists.

They are fantastic for learning new skills, building collaborative networks, and honing scientific writing.

https://t.co/h5EwMA4Ezz

[Stanley E. Strawbridge @StanStrawbridge]

⏰ Deadline in two weeks! ⏰

Work at the interface of biology + computation to build a virtual human embryo to predict developmental success and failure.

Happy to answer questions!

[Rory Cooper @rorylcooper]

🚨 Come join us @sheffielduni for a PhD on the evolution and development of feathers and flight! 🐣🔬

This project is supervised by @Mattowers1 @AlexGFletcher, and I'm excited to be involved as a project advisor. Please share!

https://t.co/NHZLR3hXG6

[Stanley E. Strawbridge @StanStrawbridge]

🚨 PhD Projects 🚨

We are advertising two UKRI funded PhD projects at
@sheffielduni through the @The_MRC with @AlexGFletcher and the @EPSRC with @emmafromthelab . #stemcells #development #embryology #reproductivephysiology #mathmaticalmodelling #quantitativebiology

[Development @Dev_journal]

Embryonic chimeras: donors in, hosts out

Read this Research Highlight showcasing work from @StanStrawbridge, @AlexGFletcher, Jennifer Nichols and colleagues (@SCICambridge @PDN_Cambridge @Cambridge_Uni @shefmathbio @sheffielduni @mrc_hgu @EdinburghUni):
https://t.co/lddUNPvGAu

[Stanley E. Strawbridge @StanStrawbridge]

Finally, a career highlight, we made it into cellysally's #PaperThemeTune s:

https://t.co/OKipLXoooE

[8/8]

[Stanley E. Strawbridge @StanStrawbridge]

🚨 New paper out in Development! 🚨

We show that donor embryonic stem cells (ESCs) reshape the developing mouse embryo, not just by what they signal, but where they push.

📄 https://t.co/UDW6Vly1M2

[1/8]

[Stanley E. Strawbridge @StanStrawbridge]

Also, check out the behind-the-scenes interview on my path in science, a eureka moment, and what I do when I choose to leave the lab:

🎙️ https://t.co/7NehjIXxer

[7/8]

[Stanley E. Strawbridge @StanStrawbridge]

10/10 Thanks to:
@The_MRC
@wellcometrust
#SãoPauloResearchFoundation
@jsps_sns
#UEHARAMemorialFoundation

[Stanley E. Strawbridge @StanStrawbridge]

1/10🧵New preprint! 🚀
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉https://t.co/23sG6oChIW

[Stanley E. Strawbridge @StanStrawbridge]

9/10 @SCICambridge @PDN_Cambridge @BabrahamInst @CamBiochem @Cambridge_Uni @ScienceShef @sheffielduni @aberdeenuni @EdinUni_IGC @mrc_hgu @usponline @LSI_Exeter @UniofExeter