1/4🧵 New paper out! We built T-ChroNet, a method to track how enhancers and regulatory elements change over time — and figure out who's driving them.
Read more → https://t.co/CuVnDMvyoP
1/4🧵 New paper out! We built T-ChroNet, a method to track how enhancers and regulatory elements change over time — and figure out who's driving them.
Read more → https://t.co/CuVnDMvyoP
3/4 We tested it on macrophage activation, mouse liver development, and pediatric leukemia progression. Recovered known regulators, found new ones too, from just ATAC-seq or ChIP-seq.
I sincerely appreciate the enriching six months I've had conducting research at the @meduni in the Barozzi's lab.
Working on exciting projects has been an incredible experience that helped me develop new proficiencies I can bring back to Rome.
🇮🇹Lavorare con colleghi che si mettono in gioco sempre è una fortuna da non sottovalutare!
Congratulazioni @StefanoDiggio 🥳
🇬🇧Working with colleagues who always challange themselves is a fortune not to be underestimated!
Here we demonstrate how epistatic interaction between KEAP1 mutations and associated copy number alterations reduce immunotherapy efficacy sustaining a COLD immune microenvironment. Thanks to all the contributors, incredible scientific journey, and interdisciplinary effort!
Il vincitore del #PremioFrancescaMartini è Stefano Di Giovenale, con Tesi su "La caratterizzazione del reguloma della Leucemia Linfoblastica Acuta pediatrica rivela meccanismi di evoluzione tumorale"
👉🏻https://t.co/7dDUoeFyv5
#CancerResearch#leucemie#biostella#SciComm
Grazie alla commissione per aver riconosciuto positivamente il mio lavoro. Questo premio è una grande motivazione per continuare su questa strada! @Nana_ETS
🏆 Proclamazione del vincitore Dott.Stefano di Giovenale , Università di Roma Tor Vergata, Iscritto al Dottorato di ricerca in Data Science, con una Tesi su "La caratterizzazione del reguloma della Leucemia Linfoblastica Acuta pediatrica rivela meccanismi di evoluzione tumorale".
Super excited to see my first graphical #abstract on the #cover of @JTOonline!
The latest review by @stescalera & @MaugeriSacca about the molecular functions of the KEAP1-NRF2 pathway, its role in #lungcancer and how KEAP1/NFE2L2 mutations reduce the efficacy of treatments����
Review of multifaceted biological functions of the KEAP1/NRF2 pathway in #lungcancer, expected consequences of these alterations, & key clinical studies. Genomic predictors should be conceived relying on the concept of epistatic interactions. https://t.co/fNQMYbdyP5 #LCSM
Our new study is now reachable on Biorxiv. We evaluated the enhancers’ involvement in the Pediatric Acute Lymphoblastic Leukaemia progression! Follow the link for the complete paper. https://t.co/vUfI31IUve
#Genomics#Biology#Epigenomics
Excited to share the new preprint from Fanciulli lab @IREISGufficiale on https://t.co/207RyvLfhP . We wanted to know how Multiple Myeloma cells cope with transcriptional stress, and we found that: Stress UP -> Che-1 / NEAT1 UP -> DNA: RNA hybrids UP -> IFN UP -> Poor prognosis.
"Laureata in biologia molecolare" che stamattina sei entrata nel negozio dei miei genitori a spiegare che gli verrà il Parkinson a causa dei metalli pesanti contenuti nel vaccino anticovid, consigliando anche degli integratori per prevenire questi effetti
1/3