Stephan Ong Tone MD PhD

Cornea Specialist, Clinician-Scientist, Fuchs dystrophy & corneal regeneration researcher @Sunnybrook l @UofTDOVS l @UofTmedicine | @LMP_UofT | Opinions my own

[Stephan Ong Tone MD PhD @StephanOngTone]

I’m proud to share our publication in @SciReports demonstrating how the most common mutation in #fuchsdystrophy in TCF4 can promote increased corneal endothelial cellular migration by altering microtubules.
@FB_Canada @Sunnybrook @UofTDOVS
https://t.co/0kTDxhI7HL

[Stephan Ong Tone MD PhD @StephanOngTone]

Excited to share the first paper from my lab. We validated Canadian eye bank prepared preloaded DMEK tissues, and have now started offering this to Canadian surgeons and their patients.
@Sunnybrook @UofTDOVS

https://t.co/MgvxAf11TK

[Stephan Ong Tone MD PhD @StephanOngTone]

Proud to be part of this landmark paper using patients’ own ex-vivo expanded stem cells to treat limbal stem cell deficiency @MassEyeAndEar @Sunnybrook @UofTDOVS #stemcells #cornea Cultivated autologous limbal epithelial cell (CALEC) Science Advances https://t.co/hT7ph1jFO6

[Stephan Ong Tone MD PhD @StephanOngTone]

@HonSing @BenLok @IacovosMichael @CarolSchuurmans @hansenhe7 @RenwickLab @SupremeHaggis @TracyMcgaha @Sunnybrook @QueensCRI @UHN Congrats!

[Stephan Ong Tone MD PhD @StephanOngTone]

Med student Stephanie Jarvi presenting our work on developing EVs as a therapeutic for corneal transplant rejection @UofTDOVS research day. @UofT_LMP @Sunnybrook @HonSing

[Stephan Ong Tone MD PhD @StephanOngTone]

Masters student Narisa Dhupar presenting our work validating preloaded DMEK at @UofTDOVS research day. @UofT_LMP @Sunnybrook

[Stephan Ong Tone MD PhD @StephanOngTone]

Undergrad Keya Patel presenting our work on EMT, TCF4 and #FuchsDystrophy @jjudyyan @UofTDOVS @UofT_LMP @Sunnybrook

[Stephan Ong Tone MD PhD @StephanOngTone]

Great presentation by Masters student Ness Little on AAV gene therapy for #FuchsDystrophy at @UofTDOVS research day. @Sunnybrook @UofT_LMP

[Stephan Ong Tone MD PhD @StephanOngTone]

Congrats to @CarolSchuurmans on leading this grant. Exciting work being done @Sunnybrook

[Sunnybrook Health Sciences Centre @Sunnybrook]

A research team led by scientist @CarolSchuurmans has been awarded a $24 million New Frontiers grant to develop a game-changing approach to combat incurable neurological disorders, like Alzheimer’s, stroke and epilepsy.

Learn more about the project: https://t.co/e9gsuFYnnN

[Stephan Ong Tone MD PhD @StephanOngTone]

The future of eye care is here. Amazing work being done here at @Sunnybrook @UofTDOVS @UofT_DoM @FB_Canada #genetherapy https://t.co/0hAuKsoVjC

[Stephan Ong Tone MD PhD @StephanOngTone]

https://t.co/r2wK7xRYSn

[Stephan Ong Tone MD PhD @StephanOngTone]

Corneal crosslinking is an important treatment for #keratoconus. In this study we look at subjective and objective measurements of corneal haze and it’s effect on vision in 483 eyes. #eye #vision

[Stephan Ong Tone MD PhD @StephanOngTone]

As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. This video-based educational curriculum is a comprehensive reference for OGI repair. https://t.co/I1JIOB5aRQ

[Stephan Ong Tone MD PhD @StephanOngTone]

@LabFerguson @FergusonottawaS @IsabelleAubert Congrats @IsabelleAubert !!

[Stephan Ong Tone MD PhD @StephanOngTone]

Honoured to be awarded with the High Impact Research Grant to study the therapeutic potential of placental-derived molecules for corneal transplant rejection and injuries. @restoresight @HonSing @Sunnybrook @UofTDOVS @LMP_UofT @UofT_DoM

[Michel Cayouette @MichelCayouette]

Excited to share our latest paper (long in the making!) in which we identify BCOR as a novel corepressor for CRX/OTX2 in the retina and show that mutations in BCOR cause retinal degenerations in humans. See thread below if you want to know more.
https://t.co/HceYmhgBw9

[Stephan Ong Tone MD PhD @StephanOngTone]

Congrats to @LMP_UofT SURE summer student Keya Patel and @jjudyyan on their 1st prize poster on #Fuchsdystrophy and #EMT! #OngToneLab See all the prize winners 👉 https://t.co/lKEtdjiFlv

[Fighting Blindness Canada @FB_Canada]

FBC-funded researcher Dr. Ong Tone swapped his white coat for a cycling jersey at this year's Cycle for Sight event in Toronto. He & his team helped raise $14,500 for vision research.

Learn more about his research & what inspires him: https://t.co/OzCdHAl3hQ

#CycleForSight

[Stephan Ong Tone MD PhD @StephanOngTone]

We had a great time at @FB_Canada Cycle for Sight. We want to demonstrate to our kids the importance of living an active lifestyle, contributing back to the community and supporting vision research. #eye #fuchsdystrophy https://t.co/NS28KvKKtg

[Stephan Ong Tone MD PhD @StephanOngTone]

Great Father’s Day weekend with my son and family @FB_Canada #cycleforsight to support vision research. @UofTDOVS @Sunnybrook

[Doug Earle @EarleDoug]

@StephanOngTone and his son takes to the road @FB_Canada #CycleForSight to support critical #vision #research

Visit https://t.co/ny2hLTztyn and make a gift to inspire @StephanOngTone as he pedals for the cure today to fight #blindness #cornea @Sunnybrook @UofTDOVS