Really excited to share my first paper from the @JohnWhitneyIIDR lab, alongside an amazing grad student, Polina. We identify a chaperone family required for the folding of a domain of T7SS toxins, and solve the structure of the chaperone-toxin complex. https://t.co/qjxFWmojEz
Excited to share our latest work with @AlbertoMarina14 and @AvigdorEldar labs, where we decipher the mechanism by which SPβ-like phages sense the SOS response to control the lysis–lysogeny switch. https://t.co/rYtcKeJu6f
https://t.co/4otXMNdonm
Exciting to see a plethora of toxin/antitoxin systems (e.g., retrons, type II) identified in P. aeruginosa genomic islands with limited representation in DefenseFinder, etc.
🚨PhD Opportunity Alert🚨 Join me,@DrSuzieHumphrey and Donal Wall to investigate how environment shapes anti-phage defences & prophage–prophage conflict in Pseudomonas aeruginosa. Apply here: https://t.co/jVVmyuXaiT
Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs@DurBiol https://t.co/AsZjImMSXW
A broad-spectrum, contact-independent antimicrobial that is neither a nonribosomal peptide nor a BGC- assembled small molecule from @JakeColautti@StephenRG97@JohnWhitneyIIDR
.@jrpenades (@imperialcollege) and colleagues published a new review on #phage satellite genetics, ecology and #evolution, diving into how these elements impact bacterial evolution and virulence.
https://t.co/rXRzDqHezb
Some really cool work from @JakeColautti in the @JohnWhitneyIIDR lab on a family of contact-independent, broad spectrum protein toxins that target Gram-positive bacteria.
Pleased to share that my main Sir Henry Wellcome Fellowship project is now published! This study provides mechanistic insights into Zorya II function. Grateful to all who contributed! Read it here:https://t.co/NLxLQNpCMV
The lab is now up and running at New England Biolabs @NEBiolabs! I'm looking for a postdoc to study phage defence systems. If you'd like the academic freedom to publish but the resources of industry, then take a look 🤓😃 https://t.co/v5V3STDowa
Love phage-bacteria interactions, anti-phage systems, and a sprinkle of evolutionary biology? There’s still time to apply and join our team in Glasgow at @UofGSii !
Happy to share this story from my PhD @foster_lab & @steverenshaw - with @becky31290 in Ken Bayles’ lab & @JosiePyrah - we show that oxacillin & tetracycline display synergy against S. aureus biofilms & during infection in zebrafish!
@MM_Sheffield@unmc
https://t.co/mc2lVSMY1i
EMBO Postdoctoral Fellowships support internationally mobile postdoctoral researchers in Europe and around the world. Apply here (next cut-off date is 14 February):
https://t.co/MchFNj6TsE
#ResearchFunding#LifeSciences