Associate Principal Scientist at Bicycle Therapeutics. Former PhD and PDRA in Spring lab (Chemistry) and Carroll lab (CRUK CI) at University of Cambridge
📢 Exciting Postdoctoral Research Associate opportunity for a chemist with research experience in organic synthesis and/or chemical biology is now available in our group. For more info check https://t.co/edAnOEITRL 📢
'Antibody dual-functionalisation enabled through a modular divinylpyrimidine disulfide rebridging strategy' by David R. Spring & Abigail R. Hanby et al @SpringGroupChem@ChemCambridge#OpenAccess 🔓
https://t.co/xkY5mBfyJY
We're delighted to share our most recent work in antibody conjugation, featuring all-in-one disulfide bridging using TetraDVP reagents. Now in @ChemicalScience, check it out! https://t.co/3TSxum0Zlx
@ChemCambridge
New 🔥 article from Ian Paterson, @nelsonyslam and first author Tegan Stockdale at @chemcambridge 🔓
'A synthesis-enabled relative configurational assignment of the C31–C46 region of hemicalide'
https://t.co/aXjO6KIVzj
David Spring at @ChemCambridge, Jason Carroll at @CRUK_CI and colleagues use divinylpyrimidine reagents for the synthesis of antibody–drug conjugates.
@springgroupchem
https://t.co/qZCtgfsWaV
A funded PhD position is available for those interested in organometallic, organic synthesis, radical chemistry and catalysis @TheKumarLab1@UCLChemistry
RTs greatly appreciated.
PhD opportunity on @FindAPhD: https://t.co/5AUIYjDILR
Are you passionate about microbiology and chemistry? @EachanJohnson and I have the perfect PhD project for you! Join us @TheCrick to work on TB drug discovery. RT highly appreciated! #chemtwitter#ukchemjobs#chemjobs
https://t.co/il6i2fqd8i
If you are interested in doing a PhD in organic synthesis and photochemistry have a think about this opportunity in @NappiGroup! Deadline: August 15th! RT much appreciated thanks!
If you are interested in a PhD in organic synthesis and photochemistry then have a think about this opportunity in the @NappiGroup! RT is much appreciated! Thanks! More info in our website: https://t.co/Q22xO32Hzd
We're happy to share our most recent work in protein modification published in @ChemicalScience! Our vinylheteroarene linkers can chemoselectively functionalise cysteine residues to give stable bioconjugates. @ChemCambridge@CRUK_CI@ASTRAZENECAUK
https://t.co/dSRT0e4wA1
Check out my most recent publication in Chemical Science! This was a project I have been working on since the start of my PhD, so it's really nice to see it published! Thanks to everyone involved!
https://t.co/Njxriv4nCn
I'm looking for a #postdoc in protein #biochemistry to join my lab on a @novonordiskfond funded project on cholesterol transport proteins. Deadline is July 2nd but I will be assessing applications as they come in so apply soon! Please RT and share :) https://t.co/5PoRQua2Ts
Check our this review on cyclisation strategies for the stabilisation of peptides with irregular conformations by @YuHengLau and colleagues @rsc_medchem
Great summary of #peptidomimetics that recapitulate non-repetitive secondary structure elements
https://t.co/4HxBJeFxK8
Have you seen the latest #openaccess Communication from David Spring & colleagues @SpringGroupChem@ChemCambridge? Check out 'A dual-enzyme cleavable linker for antibody–drug conjugates' here 🔓 👇 https://t.co/aRmLLy0LG0
From Natural Product Synthesis, read 'Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents' by Ian Paterson & colleagues @ChemCambridge https://t.co/mLNSwqh5bS
A β-galactose linker for cleavage by lysosomal enzymes to release a toxic payload (MMAE) in targeted cells by @SpringGroupChem et al. https://t.co/eTj4j6SRML
We’re happy to share our most recent work into ADC linker chemistry, featuring a highly hydrophilic, dual-cleavable sulfo-galactose motif. Check it out! @ChemCommun@ChemCambridge@CRUK_CI@GSK https://t.co/HfKhusaku2