Steven Lang, M.D.

Pediatric genetics resident physician @bcmgenetics
@BCM_Pediatrics | M.D. 23' @umiamimedicine

[Michael Wangler @mfwangler]

Impact Statement: Completion of this Specific Aim will make us know more than you can possibly imagine

[Michael Wangler @mfwangler]

A nice demonstration of peroxisomes in chronic disease. The role of Peroxisome in Diabetic Neuropathy

https://t.co/JWCjFwaqWN

[Michael Wangler @mfwangler]

How should we go about discovery in science in four easy steps:

Step 1. Based on available evidence propose a hypothesis about some aspect of nature. Don’t listen to those who try to shoot it down right away because it isn’t dogma. Aren’t we trying to discover new things? Do listen to those who point out more “available evidence.” Maybe you didn’t know something fundamental. Maybe the experts do know things you left out. Study hard, refine your idea. You want a new idea not a naive idea, but if in doubt just go with a naive idea. It will work out in the next steps.

Step 2: Predict things that would result from your hypothesis. Don’t make your predictions flexible that you could change or things that we already know. Do make them very specific. It’s like a bet that you lock in. It is a consequence of your hypothesis.

Step 3: Go test the predictions. Do experiments that directly address the prediction. If you are trying to prove yourself right you are going to shortchange your experiments. The best question to ask is what evidence would falsify the prediction. Do that experiment first! Don’t do something that you already know the answer to (if you already knew the answer please go back to step 1). Do include all the controls, account for all the conditions and gather the data in the most objective way possible. Try to ignore what you want to happen and just observe what does happen. Key point is you always collect data the same way that you can document and others could repeat and get the same result.

Step 4: Do your results disagree with your prediction?
Yes- congratulations your hypothesis is wrong, the data have spoken go back to step 1.
No- you might be onto something, but calm down you are probably still wrong, go back to Step 3. If you get back here over and over you might have something! Is it time for a new hypothesis?

[Steven Lang, M.D. @Steven_Lang97]

@AudraIness 😊

[ABMGG @TheABMGG]

Our Fall newsletter went out this week!

Read the latest information from the Board on exams, Continuing Certification and more!

[Steven Lang, M.D. @Steven_Lang97]

@AudraIness You will be a great Dr Mom !

[Steven Lang, M.D. @Steven_Lang97]

@bcmgcprogram Congratulations!

[Nathaniel H Robin @NatRobinMD]

Our study on why residents and young faculty chose genetics as a career has been published. No surprise- mentorship!

https://t.co/QnYoALKx0Y

[Steven Lang, M.D. @Steven_Lang97]

@erkinozel_md Congratulations Dr. Ozel !

[Steven Lang, M.D. @Steven_Lang97]

@NargesMaskan @UCLA @umfrostderm @HMechaber incredible ! Congrats Narges !

[Steven Lang, M.D. @Steven_Lang97]

@FrancescoSau_BS Congratulations Dr. Sautto !!!

[Steven Lang, M.D. @Steven_Lang97]

Excited to share our recent paper written with mentors from my medical school alma mater @umiamimedicine @HIHGatUM in partnership with @UDNconnect

https://t.co/mkUJAy9FkK

[StudyRare 🧬 @studyrare]

A 43-year-old woman at 21 weeks gestation presents for a prenatal ultrasound. An amniocentesis performed at 16 weeks showed trisomy 13. Which of the following findings on ultrasound would be most characteristic of a fetus with trisomy 13? #GeneChat #obgyn

[Steven Lang, M.D. @Steven_Lang97]

@OGdukeneurosurg Ah yes, the French plague !

[Steven Lang, M.D. @Steven_Lang97]

@jbcarmody 😢

[Steven Lang, M.D. @Steven_Lang97]

@GavinPrestonMD Nurses taught me everything practical in neonatology

[Steven Lang, M.D. @Steven_Lang97]

@TDrivas @TheABMGG Will our scope ultimately fall into ultra-rare multi-systemic disease ?

[Steven Lang, M.D. @Steven_Lang97]

@TDrivas @TheABMGG Also what is the role of the medical geneticist in an era of rapid and affordable sequencing ? Are we really needed to make diagnosis on clinical grounds when any doc can order a test ?

[Steven Lang, M.D. @Steven_Lang97]

@TDrivas @TheABMGG @prof_dasgupta Ah Dr Dasgupta, just noticed we shared the same article haha ! I'm curious as well what realm of medicine geneticists will be able to lay claim to? I.e. gene therapy for SMA is managed by neurologists

[Steven Lang, M.D. @Steven_Lang97]

@TDrivas @TheABMGG Thank you Dr. Drivas, reminds me of a recent paper in GIM "The evolving role of medical geneticists in the era of gene therapy: An urgency to prepare".