New in Obesity Science & Practice 📢
Our network meta-analysis of oral GLP-1 RAs in adults with overweight/obesity without diabetes found that high-dose oral semaglutide and orforglipron cut body weight by roughly 11–12% vs placebo.🔗
Read more: https://t.co/si5D3HinMi
🩺 Aldosterone synthase inhibitor lorundrostat is showing encouraging data:
📉 ~7 mmHg reduction in 24‑h SBP vs placebo in RCTs.
🛡️ Generally well tolerated with protocolized monitoring.
⚠️ ⬆️ Hyperkalemia & hyponatremia → close lab follow-up essential
https://t.co/1CaJFF3pju
👉This meta-analysis included 13 real-world studies.
👉Tirzepatide achieved a mean HbA1c reduction of 0.91% and a weight loss of 9.7 kilos from baseline.
👉 Overall, 64% of tirzepatide users reached HbA1c < 7%.
https://t.co/w7mXOtoH0t
We've reported one of the rarest occurrences where secondary diabetes caused diabetic striatopathy. It underscores d critical role of hyperglycemia in decompensation of precarious striatum leading to acute onset movement disorders @TheEndoSociety@IndiaESI
https://t.co/L355sVOwvf
Second OA from thesis. First evidence showing LEAN T2D may have lower cognitive functioning than the non-lean counterpart. Needs confirmation with larger studies exploiting body composition analysis.
📢 Anthropometry and Cognitive Impairment in Type 2 Diabetes
How does body composition influence cognition in patients with type 2 diabetes? This new study explores the relationship between anthropometric measures and cognitive performance in an Indian cohort, highlighting that lean patients with T2D showed a higher prevalence of cognitive impairment compared with their obese counterparts.
The findings emphasise the importance of considering body composition when assessing cognitive risk in diabetes and point to opportunities for future research on modifiable factors.
🔗 Read the full article: https://t.co/AT3HMWPXaD
#Type2Diabetes #CognitiveImpairment #Anthropometry #Endocrinology #MedicalResearch #touchENDOCRINOLOGY
Real-world data show tirzepatide benefits for CV outcomes in T2D.
👉Tirzepatide may help lower the risks of heart failure, stroke, and acute coronary syndrome.
👉Tirzepatide is also linked with reduced major cardiovascular events and all-cause death.
https://t.co/7f5iQTTFxy
Somapacitan has a favorable safety profile, showing no rise in serious adverse events, a lesser effect on glucose homeostasis, comparable efficacy, and improved convenience compared to daily Growth Hormone.
Our latest meta-analysis.
https://t.co/Wh9ApXbEiX
Second paper from DM thesis. Specifically addressed difference b/w cognitive status of lean & non-lean T2D. Novel observations. Should be further investigated with larger samples and simultaneous use of body composition analysis. @touchENDOCRINE@IndiaESI
https://t.co/0aj4nbOGIu
Life becomes easy with the wise usage of acronyms! @SanjayKalraDr1
1st awareness program organized by ESI Diabetes in Pregnancy Task force @IndiaESI@saptarshi5
https://t.co/cFtXoE7t5u