Lu Sun

Assistant Professor at UT Southwestern Medical Center studying how glial cells sculpt the nervous system. Views are my own.

[Lu Sun @SunLab19]

Excited to introduce four new mouse lines described in our recent study @YiheZhang97 (soon available from JAX), including two lines for studying TFEB in broader contexts (TFEB 6xMyc, JAX#041044; Rosa26-TFEBS141A;S210A-Halo, JAX#041043) and two new KI lines for myelinating OLs.

[Stanford University @Stanford]

The most important briefings of the day.

Karl Deisseroth, professor of bioengineering and of psychiatry and behavioral sciences, shares the news of his Nobel Prize with his kids.

[Jerome Staal @NeuroStaal]

This study identifies #oligodendrocytes as active contributors to #cognitive decline in #aging, by leveraging a unique #human brain bank with >70 years of associated cognitive data combined with experimental modeling of oligodendrocyte dysfunction. #Glia
https://t.co/exDN7KJ4st

[@KlingensteinOrg @klingensteinorg]

Thank you Lu Sun, Ph.D. for presenting his talk, "Cellular and Molecular Mechanisms Governing Neuron-Glial Interactions" at the recent Klingenstein Fellowship Awards in Neuroscience Conference. @SunLab19

[Eric N. Olson @Transactivator]

"Find Your Way" - Olson strikes inspiring chords in musical keynote at Graduate School commencement - Center Times Plus, UT Southwestern https://t.co/UchJjr8Z6Y via @@utswnews

[Lu Sun @SunLab19]

@SSebastianChoi Thank you, Sebastian!

[Lu Sun @SunLab19]

Excited to share our recent PNAS paper (led by @Dani_B1256): https://t.co/5gm5E4yiQQ, where we discovered the mechanisms governing myelin integrity during the onset of myelination. We are grateful to collaborate with Ellisman lab (UCSD), @WertLaboratory, and UTSW EM Core (1/6).

[Lu Sun @SunLab19]

@WalterWChen1 Thank you, Walter!

[Lu Sun @SunLab19]

This work was supported by UTSW Endowed Scholar Funds @UTSWMedCenter, @utsweye, @UTSWBrain, @NatEyeInstitute, @klingensteinorg, @czi.

[Lu Sun @SunLab19]

These defects are accompanied by prolonged visual signal transduction. We speculate that this mechanism that safeguards myelin integrity during early development might also play roles in myelin breakdown during neurodegeneration, where dysmyelination is a hallmark.

[@KlingensteinOrg @klingensteinorg]

The 2026 Klingenstein Fellowship Awards in Neuroscience Conference brought together current and past fellows, distinguished advisors, and colleagues for top-notch science, engaging discussions, slide and poster presentations, and community-building.

[Lu Sun @SunLab19]

@YueluUIowa @ZhangTingxin Thanks and hope all is well with you and your new lab in Iowa!

[Lu Sun @SunLab19]

Today we say goodbye to @ZhangTingxin, an outstanding postdoc and research scientist in our group, as he begins his independent lab at SUSTech (the first one from our lab!). He published our group’s first paper and has another under review. Congratulations and best of luck!!

[UT Southwestern O'Donnell Brain Institute @UTSWBrain]

OBI Investigator, Lu Sun, Ph.D. (right), & Aksheev Bhambri, Ph.D., developed a new research tool that sheds light on myelination. Learn how the discovery is providing deeper understanding of how neurological disorders like multiple sclerosis develop. https://t.co/jlkuyQCFc8

[Lu Sun @SunLab19]

We made the Enpp6-CreERT2 mice available from Jax: https://t.co/JNmQa4LI6F

and updated the premyelinating oligodendrocyte multiomic website: https://t.co/vvPG0p4zU8

[Lu Sun @SunLab19]

Glad to share our published version: “ Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms”, led by @AksheevB

https://t.co/V09WCcX2A8