Jian Xu

We are a group of scientists & physicians passionate about #epigenetics #metabolism #genomics #leukemia #hematopoiesis #erythropoiesis #cancer #stemcells

[Jian Xu @JianXuLab]

@leonard_zon Congrats, Len! So well deserved👏

[Ruud Delwel @DelwelRuud]

Erasmus Hematology Lecture, April 20th at 16.00 CET!

Speaker: Jian Xu, from St. Jude Children’s with
"Enhancer therapy in the era of genome editing"

Link: https://t.co/iy4iEYnJA3
ID: 842 7366 0925

Spread the news!

[Jian Xu @JianXuLab]

@ZhouLaboratory @Yun_Nancy_Huang Congratulations! Cool study!

[ISEH @ISEHSociety]

We are excited to announce the full Mini Symposium program featuring the short talks selected from submitted abstracts! Don't miss the chance to view groundbreaking research and choose the top short talk. View the full program and register ➡️ https://t.co/MqtELa0abR

[Elizabeth McKenna @ElizSMcKenna]

ICYMI in @CD_AACR: LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture - by @thechuan3, @YuannyuZhang, @JianXuLab, and colleagues @StJudeResearch

[Jian Xu @JianXuLab]

@leonard_zon Congratulations Len!! So well deserved👏🎉

[Jian Xu @JianXuLab]

@etrompouki A very important study. Congratulations Eirini!

[Elvin Wagenblast @Elvin_Wag]

Grateful to @JianXuLab for this perspective highlighting how oncogenes, developmental ontogeny, and cellular plasticity intersect in pediatric leukemia, alongside the JMML study by @mp_hartmann and @dblipka1. @BCD_AACR @CD_AACR https://t.co/n9cN5J4hz1

[Jian Xu @JianXuLab]

@Elvin_Wag @mp_hartmann @dblipka1 @BCD_AACR @CD_AACR It was a great pleasure to share our view on these important and intriguing studies. Congrats to all authors!

[Jian Xu @JianXuLab]

@etrompouki @CD_AACR @StJudeResearch Thanks you Eirini !! It was great seeing you at ASH

[Jian Xu @JianXuLab]

Excited to share our new study published online today @CD_AACR. Beyond mutagenesis, we show that LINE-1 locus-specific transcription reshapes 3D genome architecture to control cancer gene expression @JianXuLab @StJudeResearch
https://t.co/oEmNj8IGf9

[Jian Xu @JianXuLab]

@Gerta_Hoxhaj @CD_AACR @StJudeResearch Many thanks, Gerta!

[Jian Xu @JianXuLab]

@YanLiu_Lab @CD_AACR @StJudeResearch Many thanks, Yan. Happy New Year and hope to catch up soon.

[Jian Xu @JianXuLab]

@Elvin_Wag @CD_AACR @StJudeResearch Many thanks, Elvin. It was great to catch up at ASH and congrats on your recent paper in Cancer Discovery!

[Jian Xu @JianXuLab]

@TrowbridgeLab @CD_AACR @StJudeResearch Thank you, Jen! It was great to briefly catch up at ASH. Happy New Year!

[Jian Xu @JianXuLab]

@LilingWanLab @CD_AACR @StJudeResearch Thank you Liling!

[Jian Xu @JianXuLab]

@KentsisResearch @CD_AACR @StJudeResearch @KathleenHBurns @bengrbm Thank you, Alex. Always grateful for your thoughful discussion and suggestions!

[Jian Xu @JianXuLab]

@Zhu_Lab @CD_AACR @StJudeResearch Thanks Hao. Hope you are having a great start of new year!

[Cancer Discovery @CD_AACR]

Now online: LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture https://t.co/GizIJVWxuK

[Jian Xu @JianXuLab]

@LilyHuangLab @CD_AACR @StJudeResearch Thank you, Lily!

[St. Jude Research @StJudeResearch]

Scientists discovered cancer cells use interactive LINE-1 retrotransposon regions to reshape 3D genome architecture, enhancing oncogenic gene expression. This mechanism links LINE-1 activity to cancer development & highlights potential therapeutic targets. https://t.co/4VJ5mGxn4t