Ayesha Khan, Ph.D.

Clinical Microbiologist➕Infectious Diseases Scientist 🔸Artist✖️Writer✖️Abolitionist decoding science of justice & neurodivergence🔸 Instagram➖wokescientist

[JClinMicro EIC @JClinMicro]

Metagenomic Sequencing as a Pathogen-Agnostic Clinical Diagnostic Tool for Infectious Diseases: a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies

https://t.co/odvU4v3r1b @ASMicrobiology

[Mayo Clinic Infectious Diseases @MayoClinicINFD]

Weekend Digest

Name the pathogen!

5 Clues: TMP-SMX, levofloxacin, minocycline, ceftazidime, ticarcillin-clavulanic acid

[IDSA @IDSAInfo]

Direct contact w/ COVID-19 patients increased the likelihood of seropositivity, but health care workers who wore a mask during exposures were less likely to be seropositive, a study in a recent CID supplement found. https://t.co/yWINLbFSXP #ClinInfectDis #IDSAJournals @CDCgov

[IDSA @IDSAInfo]

A new multicenter case-control analysis in CID found that during March–May 2021, SARS-CoV-2 mRNA vaccines were highly effective at preventing COVID hospitalizations among U.S. adults.

📄:https://t.co/Hyj3whzd3d #IDSAJournals #ClinInfectDis

[Céline Gounder, MD, ScM, FIDSA 🇺🇦 @celinegounder]

A huge proportion of SARS-CoV-2 is transmitted by people who have no symptoms.
https://t.co/k4W4zAVUcY
(note that this data is pre-Delta)

[Ayesha Khan, Ph.D. @Superbug_Hunter]

@MicrobeNat @CPSolvers @cullen_lilley @richdavisphd @grepmeded @andreaprinzi Omg thank you! This is a great resource!

[JClinMicro EIC @JClinMicro]

Excellent resource for micro boards prep!

[Ayesha Khan, Ph.D. @Superbug_Hunter]

New guidance for diagnosis & management of rare, high morbidity & mortality fungal infections! Featuring Trichosporon, Malassezia, Pseudozyma, Rhodotorula, Sporobolomyces, Geotrichum, Kodamaea, Saccharomyces & Saprochaete/Magnusiomyces 🍄🧫 @schuetz_audrey https://t.co/Uhk408l3LF

[Audrey Schuetz @schuetz_audrey]

Great teamwork! Expanding knowledge of these rare but important yeasts.

[JClinMicro EIC @JClinMicro]

One-Step Detection and Classification of Bacterial Carbapenemases in 10 Minutes Using Fluorescence Identification of β-Lactamase Activity

https://t.co/IJu33z7K1I @ASMicrobiology

[mICROBIO @mICROBIOsh]

Hypervirulent Klebsiella pneumoniae🦠💜
LIM Medium (Bromocresol purple) 🧫💜

📸: @DraWataru

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕💥💥 #AAC @ASMicrobiology @Superbug_Hunter @SuperBugDoc
Evaluation of susceptibility testing methods for aztreonam and Ceftazidime/avibactam combination therapy on extensively drug-resistant Gram-negative organisms #IDTwitter #medtwitter #TwitteRx
https://t.co/PbjetZ2oJ8

[Ayesha Khan, Ph.D. @Superbug_Hunter]

Out now! Promising AST methods that clinical labs can use to test synergy of 2 antimicrobials & guide combination therapy for MDR infections in future! Proof of concept w/ aztreonam + caz/avi against CRE @MMBhattiMD @SuperBugDoc @ASMicrobiology @JClinMicro https://t.co/RO3ZDv0Qdu

[Ayesha Khan, Ph.D. @Superbug_Hunter]

@MMBhattiMD @SuperBugDoc #AACJournal #IDTwitter @ASMicrobiology

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕💥💥 #AAC @ASMicrobiology @Superbug_Hunter @SuperBugDoc
Evaluation of susceptibility testing methods for aztreonam and Ceftazidime/avibactam combination therapy on extensively drug-resistant Gram-negative organisms #IDTwitter #medtwitter #TwitteRx
https://t.co/PbjetZ2oJ8

[David van Duin @davidvanduin]

"Uncertainty in evaluating treatment outcomes in carbapenem-resistant Acinetobacter baumannii infections" Commentary by @JessH_A now available in #AACjournal @ASMicrobiology @ClancyNeil @OncIDPharmd @JGPharmD
https://t.co/DhCcpcv88s

[Dr. Matt Binnicker @DrMattBinnicker]

Still wondering if there are tests to determine whether an individual with #COVID19 is “infectious”?

I had a great conversation with @JClinMicro EIC, Alex McAdam on this topic!

https://t.co/ISwSPX40nj

[Ayesha Khan, Ph.D. @Superbug_Hunter]

After a tough, long week- all I needed to life my spirits was:
- interesting cases on-call
- learning about new bugs & drugs
- open my Instagram to see someone way cooler than me share my work. Thank you @jvn ♥️
Refusing vaccines is a privilege.

#clinmicro #CovidVaccine

[Cesar Arias @SuperBugDoc]

Hot off the press in #AACJournal. Novel approaches to treat resistant Gram-negative infections are urgently needed. Antibody-drug conjugates (ADCs), primarily used in anti-cancer therapy, are promising approaches. @ASMicrobiology @asm_tmc @ARLGnetwork
https://t.co/qLTQV5vpH8

[Dr. Matt Binnicker @DrMattBinnicker]

This was a fun review to write.

Unfortunately, there isn’t a perfect test to determine if someone is infectious.

[Bobbi Pritt, MD @ParasiteGal]

Here's a Tick Tweet to remind everyone to prevent tick bites! COVID isn't the only pathogen out there to worry about. Here are 3 female Ixodes scapularis ticks (vector for Lyme disease) in unengorged, partially engorged, and fully engorged states. Yuck!

[Cesar Arias @SuperBugDoc]

Hot-off-the press in AAC. Proof of principle that you can get rid of resistance genes using CRISP_Cas system. Would it work one day? No one knows but, at least, an efficient system seems to be available
@ASMicrobiology @ARLGnetwork
https://t.co/H2nWjuOys2