Timothy Spear, MD, PhD

Physician Scientist | Pediatric Oncologist | Cancer Immunologist | Cell Therapy | Cancer Vaccines | @ChildrensPhila @CHOPCancerCntr @PennCancer

[Joseph Fraietta @JoeFraietta]

Thrilled to share our new paper in @NatureMedicine! We analyzed 783 patients (2,200+ patient-years) receiving lentiviral or gammaretroviral T cell therapies and found no evidence of high-level insertional mutagenesis. https://t.co/sNGqvjDXMt

[Penn Medicine Cancer @PennCancer]

Publication alert 🚨: Penn researchers found that combining #CARTCellTherapy with cytokine signaling inhibitors could enhance #immunotherapy efficacy in acute myeloid #leukemia and achieve improved outcomes. @anandbmdphd @NatureMedicine https://t.co/MbWYzHdSL0

[Timothy Spear, MD, PhD @TSpearMDPhD]

Congrats to @anandbmdphd for an outstanding summation of his fellowship work at @CHOPCancerCntr published today in @NatureMedicine.

[The Bhagwat Lab @anandbmdphd]

Tremendously proud to share my fellowship work, online today in @NatureMedicine. We tried to understand why CAR T therapy for AML doesn't work as well as we hoped it would, and how we can solve that. 👇🧵1/10
@PennMedicine @CHOP_Research @GillSaar https://t.co/Dkp8YsSYJ9

[ACIR @ACIR_org]

To target high-risk neuroblastoma, which expresses surface GPC2 (tumor-exclusive, but downregulated under immune pressure) and GD2 (not tumor-exclusive) and is infiltrated by CD16a+ innate immune cells [...] https://t.co/srqJwAskXw  @CHOP_Research

[Timothy Spear, MD, PhD @TSpearMDPhD]

Congrats to @wolpawlab and thank you to @hopeonwheels for this generous funding towards our research demanding more effective and less toxic therapies for neuroblastoma

[CHOP Research @CHOP_Research]

Congrats to @ChildrensPhila's Drs. Adam Wolpaw & Timothy Spear who were awarded a combined $650,000 from @hyundaihopeonwheels for #Neuroblastoma research at the nonprofit's handprint ceremony earlier this week. https://t.co/khcuueQblB

@CHOPCancerCntr

[Timothy Spear, MD, PhD @TSpearMDPhD]

Grateful to @ConquerCancerFd & @ASCO for funding our neuroblastoma neoantigen vaccine project @CHOPCancerCntr

[Conquer Cancer, the ASCO Foundation @ConquerCancerFd]

Congratulations to this year's class of Conquer Cancer Grant and Award recipients! We can't wait to celebrate with you at #ASCO24! Full list of recipients: https://t.co/mCaRLSVLik

[Timothy Spear, MD, PhD @TSpearMDPhD]

Excited to have our personalized neoantigen vaccine campaign for high-risk neuroblastoma and other pediatric cancers at @CHOPCancerCntr funded by @StBaldricks!

[St. Baldrick's Foundation @StBaldricks]

Exciting News! 📢 $1.1M to support young investigators pushing boundaries in pediatric cancer research! Meet the 2024 St. Baldrick’s Fellows and explore their innovative projects in our latest blog post: https://t.co/BfvCQ3LEaJ

[St. Baldrick's Foundation @StBaldricks]

Exciting News! 📢 $1.1M to support young investigators pushing boundaries in pediatric cancer research! Meet the 2024 St. Baldrick’s Fellows and explore their innovative projects in our latest blog post: https://t.co/BfvCQ3LEaJ

[Cancer Center @ CHOP @CHOPCancerCntr]

Congratulations to Dr. Timothy Spear for being named one of @StBaldricks 2024 Fellows!

[Timothy Spear, MD, PhD @TSpearMDPhD]

Exciting work starting between the @CHOPCancerCntr Maris Lab and @ljiresearch Schoenberger group!

[CHOP Research @CHOP_Research]

.@ChildrensPhila’s Dr. John Maris is developing a #PersonalizedCancerVaccine for #neuroblastoma patients to prevent relapse. Learn more about his novel research on Cornerstone. https://t.co/DzUDUPhcYD

[The Bhagwat Lab @anandbmdphd]

So lucky to have such a deep scientific community around.
Cc @TakasakiKMD

[Timothy Spear, MD, PhD @TSpearMDPhD]

Grateful to the @AACRFoundation for sponsoring pediatric cancer research at this years Party with a Purpose and helping fund our efforts to develop novel immunotherapies for childhood cancer @CHOPCancerCntr @ChildrensPhila

[AACR Foundation @AACRFoundation]

Party with a Purpose Scientific Achievement Awardee John M. Maris, MD, presented the Party with a Purpose Early-Career Investigator research grant to Timothy Spear, MD, PhD, a pediatric hematology/oncology fellow at @ChildrensPhila.

[AACR Foundation @AACRFoundation]

In conjunction with the Friends of the @AACR Foundation, Party with a Purpose will honor two neuroblastoma researchers from @ChildrensPhila. Learn more on the #AACRBlog: https://t.co/Cq8D7WVEb4