Tumour Immune Microenvironment Lab

Fresh lab @Radboudumc @RIMLSinstitute. / tweets by @TaurielloD

[Tumour Immune Microenvironment Lab @TaurielloLab]

Congratulations and thanks for the collaboration!

[MVermeulenLab @LabVermeulen]

Great work from PhD students Jelmer Dijksta and @HNeikes in collaboration with @TaurielloLab and Emile Voest: multi-omics and secretomics in tumor progression organoids revealing putative regulators of colon cancer metastasis, including DKK3 and DKK4

https://t.co/wnpLRHcG2F

[Tumour Immune Microenvironment Lab @TaurielloLab]

Our own Beatriz Subtil wrote a blog about the importance of #rest for academics, inspired by the work of @DrDaltonSmith.

Have a look: https://t.co/rrW1C93tVp

"...by prioritizing our rest and well-being, we become more productive, present, creative, motivated, and focused."

[Daniele Tauriello @TaurielloD]

#WorldCancerDay, has many meanings to patients, survivors, family, friends, grievers...

Besides sharing these, scientists also try to take strength and inspiration from today.

Join or support our @TranslCRCres #Walkagainstcancer
https://t.co/ed4a3DkhSN
@ROFNijmegen @radboudumc

[Nature Reviews Cancer @NatureRevCancer]

NEW Review! @TaurielloD from @TaurielloLab, @elenasanchosuil and @BatlleLab discuss overcoming #TGFbeta-mediated immune evasion in cancer.

⚡https://t.co/fxFTaX1ZIZ

@natrescancer #CancerTherapy #CancerImmunity

[soria @jsoriamd]

As tumours progress, TGFβ drives strong wound-healing programme in CAF & suppress the adaptive & innate immune system, thus facilitating #immunotherapy insensitivity.Overcoming TGFβ-mediated immune evasion in cancer is a difficult but important challenge.
https://t.co/UvQv4cpXNN

[The BATLLE Lab @BatlleLab]

With @TaurielloD from @TaurielloLab and @elenasanchosuil we have written this comprenhensive review on the role of TGF-beta over immune cell types in the TME, and the actual landscape of therapies targeting this pathway in #Cancer for @NatureRevCancer
https://t.co/3Rr805NbiV

[Nature Reviews Cancer @NatureRevCancer]

NEW content online! Overcoming TGFβ-mediated immune evasion in cancer https://t.co/vns4d1w2tt

[Daniele Tauriello @TaurielloD]

Together with @BatlleLab, @elenasanchosuil, I wrote a review on Overcoming TGFβ-mediated immune evasion in cancer in @NatureRevCancer. We are very proud of this, and I hope you will enjoy reading it.

https://t.co/c2Ff5WiXKy

[Tumour Immune Microenvironment Lab @TaurielloLab]

If you like #CRC and #immunity, you might want to check out DC (dys)function ... which is exactly what Beatriz Subtil in the lab is doing. And she wrote a beautiful review about it too! With @AlessandraCambi + Jolanda de Vries @TIL_Radboudumc

Out today: https://t.co/oEsR7YChLh

[Tumour Immune Microenvironment Lab @TaurielloLab]

New group photo from our recent and wonderful lab retreat (together with Henk Verheul & co)

[Daniele Tauriello @TaurielloD]

Congrats! to collaborators in the Moscat—Diaz-Meco lab @SBPdiscovery/@WeillCornell, for their publication on TGFB-induced suppression of PKCZ in the CRC #TME—promoting SOX2-mediated #CAF formation; using our @BatlleLab MTOs.
👉Kasashima et al. @Dev_Cell
https://t.co/s1qM20UPgP

[Madelon Maurice @MadelonMaurice]

Happy to share our latest publication in @embojournal ! We discovered an unexpected class of RNF43 mutations that confer a tumor suppressor-to-oncogene switch. Curious how? Check our video summary 👉 https://t.co/A1Zmmwrk8j @UMCU_CMM @oncodeinstitute 1/4

[Cancers MDPI @Cancers_MDPI]

Combinatorial #Immunotherapies for #Metastatic #Colorectal #Cancer
by Eline Janssen, Beatriz Subtil et al.
👉https://t.co/EZqXmuO5w5
#CRC
#immunesuppression
#tumormicroenvironment

[Daniele Tauriello @TaurielloD]

My lab's first publication is a fact!

Huge kudos to Eline Janssen, Beatriz Subtil & Fàtima de la Jara Ortiz for pulling this off in these weird times, well done!
Also thanks to our super-collaborator Henk Verheul @radboudumc.

May this be the first of many to come! 🥳🎉🥂

[Tumour Immune Microenvironment Lab @TaurielloLab]

As this is the TiMElab's first-TiME publication, this one is very special to us. We learned a lot from researching and writing it, and feel it made something positive out of the Covid-19 lockdown in the process.
Above all, we hope you find it useful!

[Tumour Immune Microenvironment Lab @TaurielloLab]

Interested in #ColorectalCancer research &
#Immunotherapy? Our review offers an overview of the field, plus a perspective towards 'precision I/O': Combinatorial Immunotherapies for Metastatic CRC https://t.co/BW1NSyEnYx via @MDPIOpenAccess @radboudumc_weetn @RIMLSInstitute

[AlessandraCambi @AlessandraCambi]

Great to see the department of #cellbiology ⁦@RIMLSInstitute⁩ ⁦@radboudumc⁩ back together again ... celebrating publications, awards and life in general 🍾 #anderhalvemeter #picnic

[Daniel Beiting @hostmicrobe]

And that's a wrap on our #RNAseq course for @CAMBUpenn! Great group of students this year. 21hrs of video lectures are up on our website for anyone who wants self-guided instruction in #rstats and @bioconductor. https://t.co/cvwTtBm1oS

[Prof. Akiko Iwasaki @VirusesImmunity]

This is a cautionary tale of how anti-Spike antibody may make COVID disease worse. In this study, the authors show that anti-Spike IgG made SARS-CoV disease worse by switching macrophage from wound-healing to proinflammatory phenotype. A thread (1/n)

https://t.co/T8ipHt5tRH

[Hans Clevers @HansClevers]

#ibiology recorded three lectures of 20 minutes each covering 30 years or research in my lab. They can be viewed at:
https://t.co/QbysC0TdcU
#stemcells #organoids @coloncancer