Paul Tesar

GirlDad | Professor @CWRUSOM developing glial therapies for neuro diseases | DPhil @UniofOxford @NIHOxCam | Co-founder @convelotx | Director @riseupneo | Foodie

[Paul Tesar @TesarLab]

So cool to see our recent paper on environmental chemicals affecting brain health on the cover of Nature Neuroscience! Congrats again to @ErinFCohn and the team. Special thanks to Ella Maru Studio @Ella_Maru for the artwork

[Nature Neuroscience @NatureNeuro]

Our May issue is now live!

https://t.co/ol5GCcPt6K

[Nature Neuroscience @NatureNeuro]

Our May issue is now live!

https://t.co/ol5GCcPt6K

[Paul Tesar @TesarLab]

Excited to share this excellent article by Teddy Amenabar @TeddyAmen in The Washingotn Post @washingtonpost. It provides a clear & balanced look at our recent discovery of a class of household chemicals that are harmful to the brain's myelinating cells.

https://t.co/magFiqBIRg

[Paul Tesar @TesarLab]

Proud to see work from our lab making its way to patients. I am hopeful that the investigational drug, ION356, being tested by Ionis will be found to be both safe & effective in people with Pelizaeus Merzbacher disease🙏
Link to our 2020 @Nature paper:
https://t.co/iWEjq3SAmp

[Forbes @Forbes]

Chemicals Found In Popular Household Products Potentially Linked To Autism, Multiple Sclerosis, Study Suggests
https://t.co/ZHlpxsATNh

[Paul Tesar @TesarLab]

Thank you @EricTopol for highlighting our paper. An open access link to the full article is here:
https://t.co/FCF3h75f6h

[Eric Topol @EricTopol]

New and worrisome: common household chemicals can directly harm oligodendrocytes, brain health
https://t.co/uaCGeP5aGg
@NatureNeuro @TesarLab @CWRUSOM Quarternary ammonium compounds (disinfectants) and organophosphate flame retardants implicated from organoids and expt'l models

[Newsweek @Newsweek]

MS and autism among brain health risks from common household chemicals

https://t.co/37zQXIA7le

[Paul Tesar @TesarLab]

Open access link to the full paper:
https://t.co/FCF3h75f6h

[Paul Tesar @TesarLab]

Common household chemicals pose a risk to the brain’s myelinating cells

Thrilled to share groundbreaking findings from our latest study led by @ErinFCohn at @CWRUSOM's Institute for Glial Sciences, in collaboration with the U.S. @EPA.
https://t.co/9gxhHu2d3y

[Paul Tesar @TesarLab]

I am also grateful to our supporters, including the @NIH_NINDS, @mssociety, @HHMINEWS, @nyscf, sTF5 Care, and the Long, Walter, Peterson, Goodman, and Geller families.

[Shane Liddelow 🍊 @LiddelowSA]

Great work by @bllclayton, @TesarLab, & the team. Such an insightful dive into modulation of astrocyte reactivity.

@ScienceLemon92 and I were honored to write the @NatureNeuro N&V on this piece - see https://t.co/v9Mo4dDGFF.

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[Nature Neuroscience @NatureNeuro]

A phenotypic screening platform for identifying chemical modulators of #astrocyte reactivity reveals histone deacetylase 3 (HDAC3) inhibitors as suppressors of pathological astrocyte reactivity

@TesarLab @bllclayton

https://t.co/obcMFZT0Jq

[Paul Tesar @TesarLab]

Read the full scientific paper here 👇
https://t.co/TWajzwSvWl

[Paul Tesar @TesarLab]

🌟Drugging astrocytes to stop neurodegeneration
I am thrilled to resurface on X to share a significant breakthrough from our team in the Institute for Glial Sciences @CWRUSOM, shining new light on the path to combating neurodegenerative diseases.
https://t.co/RmkUfwy1Wv

[Paul Tesar @TesarLab]

Together, we are redefining the future of neurological disease treatment by targeting glial cells!