The Tetrahymena Stock Center, located at Cornell University, is a centralized repository and distribution site for a variety of Tetrahymena strains and species.
We're back!! The Tetrahymena Stock Center is resuming activity. We can ship cells upon request. Plasmids, genomic DNA media may take a bit longer than usual but are available. Questions - contact the Tetrahymena Stock Center at [email protected] .
The in vivo Tetrahymena thermophila extracellular glucose drop assay for characterization of mammalian insulin activity. Interesting discussion of use of Tetrahymena in place of the in vivo rabbit blood glucose drop assay. https://t.co/dYMQBJhtA2
Interesting technique! Swimming behavior of Tetrahymena in free-space shown by 3D tracking of fluorescent microbeads phagocytosed by the cells. 3D tracking done by using a three-dimensional prismatic optical tracking (tPOT) microscope20, which yields 3D positional information.
Three-dimensional tracking of the ciliate #Tetrahymena reveals the mechanism of ciliary stroke-driven helical swimming @CommsBio
https://t.co/yaPlln6F7Y
Cryo-EM structures tell a tale of two telomerases. Nice review of the current understanding of the molecular mechanism of telomerase. Fascinating example of the power of cryo-EM techniques for exploring structural properties underlying cellular function. https://t.co/UcBmN0QIHn
Characterization and use of Tetrahymena thermophila artificial chromosome 2 (TtAC2). The newly constructed Tetrahymena artificial chromosome TtAC2 vector was stably maintained in the macronucleus for over two months and expressed recombinant TtsfGFP. https://t.co/7EmF5JauWO
Amazing video of squirming termite gut #protists by Fabian J Weston - truly worthy winner of this year's @NikonSmallWorld competition! #aliensinourmidst (can't get enough #cilia 😍)
https://t.co/2gnu4nqNEV
Interested in using Tetrahymena for teaching purposes? ASSET offers complete kits using Tetrahymena to explore a variety of biological concepts. Check out https://t.co/IwDgNJsVGn
ASSET is BACK !
Teach biology or health to elementary, MS, HS students?
Check out ASSET's FREE 2-week loan of fully equipped kits using live protists to explore
- key biological concepts
- effects of e-cig vapor, tobacco smoke, alcohol on live cells
https://t.co/GHlBho6fLf
Beautiful figures support a model of how the attachment of the outer dynein arms (ODA) to the doublet microtubule induces remodeling and activation of the ODA complex. Nice!
NEXT
The Transport Behavior of a Biflagellated Microswimmer before and after Cargo Loading. Working biohybrid microbots - sounds like something from Star Trek!
https://t.co/6AX9DY8gyv
Protist hosts BOTH Green Algae and Purple Bacteria Symbionts! Two different endosymbionts may allow Pseudoblepharisma tenue to live in both oxygen-rich and oxygen-poor zones of muddy bogs.
https://t.co/CJ2Xp0YEg7
If you teach biology in elementary, MS, or HS, check this out! Great resource, FREE 2-week loan of fully equipped kits. Comprehensive student and teacher protocols included!
ASSET is BACK !
Teach biology or health to elementary, MS, HS students?
Check out ASSET's FREE 2-week loan of fully equipped kits using live protists to explore
- key biological concepts
- effects of e-cig vapor, tobacco smoke, alcohol on live cells
https://t.co/GHlBho6fLf
Interested in Tetrahymena as a research or teaching tool? Check out these reviews.
Tetrahymena as a Unicellular Model Eukaryote: Genetic and Genomic Tools. https://t.co/N22ua2cpNK
Tetrahymena in the classroom. https://t.co/fqG7Lfx4ql
Nanopore sequencing technologies can generate sequencing reads megabases in length that may span an entire ciliate MAC chromosome. Strategy tested in Tetrahymena, but likely can be used directly or with slight adaptation to assemble complete MAC genomes of other ciliate species.
A strategy for complete telomere-to-telomere assembly of ciliate macronuclear genome using ultra-high coverage Nanopore data @CSB_Journal
https://t.co/9tj2wZt3H6
Includes an interesting exploration of the possibility of exploiting Tetrahymena machinery for genome editing and its possible advantages over the widely used CRISPR-Cas9 system.
Evolution of the mating type gene pair and multiple sexes in Tetrahymena. Interesting discussion of likely derivation of MTA and MTB from common ancestral gene, MT genes in a unisexual species, and effects of reproductive stress om MT evolution.
DOI: 10.1016/j.isci.2020.101950
Fascinating historical summary and discussion of the origin, history, and current relevance of various theories of the evolution of multicellularity. Beautiful illustrations. Definitely worth a read by anyone interested in the human side of scientific progress!